Pyridine 5 Aminooxy Methyl 2 1h Pyrazol 1 Yl
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 5-[(aminooxy)methyl]-2-(1H-pyrazol-1-yl)-

    Specifications

    HS Code

    802894

    Chemical Formula C10H11N5O
    Molecular Weight 217.23 g/mol
    Appearance Solid (predicted)
    Solubility In Water Poorly soluble (predicted)
    Logp 1.32 (predicted)

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    Frequently Asked Questions

    As a leading Pyridine, 5-[(aminooxy)methyl]-2-(1H-pyrazol-1-yl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of this product 5- [ (aminoxy) methyl] -2- (1H-pyrazole-1-yl) pyridine?
    This is a unique chemical substance, 5- [ (hydroxycarbonyl) methyl] -2- (1H-indole-1-yl) indole. Its chemical properties are rich and complex, and it contains many wonderful properties.
    Structurally, there is an indole group in this compound, which endows it with certain aromatic properties and stability. The indole structure is widely present in many natural products and active pharmaceutical ingredients, making this substance highly likely to have specific biological activities. The hydroxycarbonyl methyl part adds polarity to it, which has a profound impact on its solubility in solution and its interaction with other molecules. The presence of polarity makes it easier for the substance to interact with polar solvents, and in some reaction systems, it can participate in the reaction process more effectively.
    In terms of chemical reactivity, the hydroxyl group on the hydroxyl carbonyl group has a certain nucleophilicity. Under appropriate reaction conditions, it can replace with electrophilic reagents, and then build new chemical bonds to derive various derivatives. The presence of carbonyl groups cannot be ignored. It can participate in various organic reactions such as condensation reactions, providing rich possibilities for the chemical transformation of the substance. The nitrogen atom on the indole ring, due to the presence of lone pair electrons, also has certain nucleophilic properties, which can participate in electrophilic substitution reactions, especially at specific positions of the indole ring, thereby changing the electron cloud distribution and spatial structure of the whole molecule, greatly affecting its chemical properties and biological activities.
    Furthermore, different groups in the substance will also interact with each other. For example, there may be an electronic effect between the indole ring and the hydroxycarbonyl methyl group, which will change the reactivity of each group, making the substance exhibit unique reaction selectivity when participating in chemical reactions. In summary, 5- [ (hydroxycarbonyl) methyl] -2- (1H-indole-1-yl) indole has abundant and unique chemical properties due to its unique structure, which may hold great potential value and application prospects in the fields of organic synthesis and drug development.
    What are the main uses of 5- [ (aminoxy) methyl] -2- (1H-pyrazole-1-yl) pyridine?
    (Hydroxyamino) methyl-2 - (1H-indole-1-yl) indole, this compound has important uses in many fields.
    In the process of pharmaceutical research and development, it is often a key active ingredient, or has unique physiological activities, and can be closely bound to specific biological targets. For example, in the field of anti-tumor drug research, it may interact with key proteins in cancer cells with specific structures, or interfere with cancer cell signaling pathways, thereby inhibiting cancer cell proliferation and inducing apoptosis, providing a new opportunity to solve cancer problems. In the field of drug development for neurological diseases, it may also regulate neurotransmission by acting on neurotransmitter receptors or related enzymes, and help treat neurological diseases such as Alzheimer's disease and Parkinson's disease.
    In the field of materials science, due to its unique chemical structure and electronic properties, it can become a key raw material for the preparation of new functional materials. For example, in the field of organic optoelectronic materials, rational molecular design and modification can be used to integrate them into organic semiconductor material systems to optimize the charge transport properties, optical absorption and emission characteristics of materials, and used to fabricate high-performance organic Light Emitting Diodes (OLEDs), organic solar cells and other optoelectronic devices to improve device efficiency and stability.
    In the field of agriculture, it may also show potential value. Perhaps it can be developed into a new type of pesticide or plant growth regulator, which can inhibit or kill specific pests or pathogens by virtue of its special structure, and is relatively friendly to the environment. When used as a plant growth regulator, it can regulate the process of plant growth and development, such as promoting seed germination, enhancing plant resistance, and contributing to the sustainable development of agriculture.
    What is the synthesis method of 5- [ (aminoxy) methyl] -2- (1H-pyrazole-1-yl) pyridine?
    To prepare 5- [ (hydroxycarbonyl) methyl] -2- (1H-pyrazole-1-yl) pyrazole, the synthesis method is quite complicated, and it needs to be achieved through multiple and delicate reactions.
    The first step is to carry out nucleophilic substitution reaction with suitable starting materials, or aromatic compounds with specific substituents, and reagents containing active hydrogen under the conditions of suitable temperature, pressure and specific catalyst. This step aims to introduce the key pyrazole structure to lay the foundation for subsequent reactions. For example, select a benzene derivative with a halogen atom substitution, and the alkali metal salt of pyrazole in a polar solvent, such as dimethylformamide (DMF), under heating conditions, the halogen atom is substituted by a pyrazolyl nucleophilic group to form an intermediate containing pyrazolyl.
    Next, modify the resulting intermediate to construct another pyrazole ring and connecting group of the target product. Or use a cyclization reaction, with the help of suitable reagents, such as acylating reagents or aldehyde compounds, and the activity check point in the intermediate, under the catalysis of acid or base, the molecular cyclization occurs. For example, the reaction of an acid chloride with an intermediate first forms an amide bond, and then under the catalysis of a base, the molecular inner ring is closed to form a skeleton containing two pyrazole rings.
    Furthermore, for the construction of the 5- [ (hydroxycarbonyl) methyl] moiety, specific functional group transformation can be performed on the above-mentioned bispyrazole skeleton. For example, a suitable nucleophilic reagent, such as a reagent containing a carboxyl protecting group, reacts with a suitable check point on the skeleton to introduce a carboxyl-containing precursor group. After that, through the deprotection reaction, the carboxyl group is released, and then through the reduction reaction, such as the use of sodium borohydride and other reducing agents, the carboxyl group is partially reduced to the hydroxycarbonyl methyl structure, so as to obtain 5- [ (hydroxycarbonyl) methyl] -2- (1H-pyrazole-1-yl) pyrazole.
    The whole synthesis process requires fine control of the conditions of each step of the reaction, including temperature, time, ratio of reactants and catalyst dosage, etc., and after each step of the reaction, purification, separation and other operations are required to ensure the purity and yield of the product to obtain a pure target product.
    What is the price range of 5- [ (aminoxy) methyl] -2- (1H-pyrazole-1-yl) pyridine in the market?
    I think what you are asking is about the price range of (hydroxyhydroxyl) methyl and (1H-imidazole-1-yl) imidazole in the market. However, the price of such substances often varies for various reasons.
    First, it depends on its quality. The quality is good, the price is high; the quality is poor, the price is low. If it is made in a fine way, the purity of (hydroxyhydroxyl) methyl and (1H-imidazole-1-yl) imidazole is very high, and its price is higher than that of ordinary products.
    Second, it is related to supply and demand. If there are too many people in the market, but there are too few people to supply, the price will rise; if the supply exceeds the demand, the price will drop. For example, when the pharmaceutical industry is booming, the price will rise if there are too many people who need these two things as raw materials; and if the number of manufacturers increases sharply and the output is too much, the price will fall.
    Third, the manufacturing cost is also a major factor. The price of raw materials, the manufacturing method, and the cost of manpower will all affect the final selling price. If the raw materials are rare, the procurement cost is huge, or the manufacturing method is complicated, and a lot of equipment and manpower are required, the cost will be high, and the price will also be high.
    As for the exact price range, it is difficult to determine. Roughly speaking, (hydroxyhydroxyl) methyl, per gram or from a few yuan to tens of yuan; (1H-imidazole-1-yl) imidazole, per gram price or between a few yuan to tens of yuan. However, this is only an approximate number, and the market conditions are ever-changing. To know the exact price, you need to ask the chemical raw material manufacturer and check the information of the industry.
    What are the safety and toxicity of 5- [ (aminoxy) methyl] -2- (1H-pyrazole-1-yl) pyridine?
    (Note: For the convenience of understanding, first write the chemical formula corresponding to the common name, (hydroxyhydroxyl) methyl corresponds to ethylene glycol monomethyl ether, and 1H-imidazole-1-ylimidazole corresponds to 1,1 '-imidazole. The following is answered in classical Chinese style)
    Looking at these two substances, (hydroxyhydroxyl) methyl, has certain danger. It is flammable, and it may cause combustion and explosion in case of open flame or hot topic. In terms of health, it is harmful to irritation. If people inhale, ingest or absorb it through the skin, it can damage the body. In light cases, it may cause irritation to the eyes, respiratory tract and skin, and in severe cases, it may cause damage to the nervous system, liver, kidney and other organs.
    As for 1,1 '-biimidazole, its stability is acceptable, and it is relatively stable under normal conditions. However, it should not be taken lightly. Although it is not as highly corrosive as common strong acids and alkalis, some experiments show that it may have a certain potential impact on living organisms. In the environment, if it is released in large quantities or through complex environmental effects, it may also slightly disturb the ecological balance.
    In summary, both need to be properly disposed of. When storing, (hydroxyhydroxyl) methyl should be kept away from fire and heat sources in a cool and ventilated storage, and stored in a separate storage with oxidants and acids. When taking it, it must strictly follow safety regulations and wear protective equipment. Although 1,1 '-biimidazole is relatively stable, it should be stored reasonably to avoid mixing with strong oxidizing and acidic substances, and should not be negligent in use to prevent accidents. In this way, it can ensure safety and avoid the risk of poisoning.