Pyridine 3 Methyl 2 Nitro 9ci
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 3-methyl-2-nitro- (9CI)

    Specifications

    HS Code

    977427

    Chemical Formula C6H6N2O2
    Molar Mass 138.12 g/mol
    Appearance Solid (usually)
    Odor Characteristic, pungent (likely)
    Solubility In Water Low solubility (organic compound, relatively non - polar)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Stability Can be reactive due to nitro group, relatively stable under normal storage conditions away from heat, light, and reactive substances

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    Frequently Asked Questions

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    What are the chemical properties of 3-methyl-2-nitropyridine (9CI)?
    3 + -Methyl-2-furanaldehyde (9CI), this is an organic compound. Its chemical properties are unique and valuable for investigation.
    From the structural point of view, the methyl group is attached to a specific position of the furan ring, and the aldehyde group is also at the corresponding check point. This structure gives it a variety of chemical activities.
    In terms of physical properties, it may be a colorless to light yellow liquid at room temperature, with a special odor. It has good solubility in organic solvents such as ethanol and ether, and its solubility in water is limited.
    Its chemical properties are active, and the aldehyde group is the key active site. It can undergo classic aldehyde reactions, such as nucleophilic addition with nucleophiles. Taking the reaction with alcohols as an example, under acid catalysis, acetals can be formed. This reaction is often used as a carbonyl protection method in organic synthesis to avoid the random participation of aldehyde groups in subsequent reactions, and the aldehyde groups can be restored by hydrolysis at a specific stage.
    Oxidation reaction is also an important property. Under mild oxidation conditions, aldehyde groups can be oxidized to carboxyl groups to generate 3-methyl-2-furanic acid; in case of strong oxidants, furan rings may also be affected, resulting in complex reactions such as ring opening.
    In addition, because it contains unsaturated furan rings, it can participate in conjugate addition reactions. The conjugated system endows the molecule with a special electron cloud distribution, making it easy to combine with conjugated nucleophiles to construct novel compounds, which are widely used in drug synthesis and materials chemistry.
    In the reduction reaction, aldehyde groups can be reduced to alcohol hydroxyl groups to obtain 3-methyl-2-furanomethanol. This product is an important intermediate in organic synthesis and can further derive many compounds.
    In short, 3 + -methyl-2-furanaldehyde has a special structure and active chemical properties. It plays an important role in many fields such as organic synthesis, drug research and development, and material preparation. In-depth study of its properties is of great significance for expanding the application of organic chemistry.
    What are the common uses of 3-methyl-2-nitropyridine (9CI)?
    Methoxy groups and ethoxylbenzene (9CI) are commonly used in a wide range of paths.
    Methoxy groups and ethoxylbenzene can be used as key intermediates in the field of organic synthesis. Due to their unique structure, they can be derived from other compounds through many chemical reactions. For example, nucleophilic substitution reactions, whose methoxy or ethoxy groups can be replaced by other nucleophilic reagents to form new carbon-heteroatomic bonds, which are essential when creating complex organic molecules.
    It can also be seen in the fragrance industry. The unique smell of methoxy and ethoxylbenzene can be used as fragrance ingredients to give products a different aroma. It can add a special flavor to fragrance formulations and is widely used in perfumes, air fresheners and various aromatic products.
    Furthermore, it has also been paid attention to in the field of medicinal chemistry. Such compounds may have certain biological activities and can become the basis for lead compounds in the process of drug development. By modifying and optimizing their structures, it is expected to find new drugs with better pharmacological properties.
    In the field of materials science, methoxy and ethoxy benzene can participate in the polymerization reaction to prepare polymer materials with special properties. Its introduction may improve the solubility, thermal stability and mechanical properties of materials to meet the requirements of material properties in different application scenarios.
    In addition, in the synthesis of dyes, methoxy and ethoxylbenzene can be used as dye intermediates to introduce chromophores through chemical reactions to create colorful and high-performance dyes, which are used in textile printing and dyeing industries.
    What are the synthesis methods of 3-methyl-2-nitropyridine (9CI)?
    The method of synthesizing 3-methyl-2-carbonylvaleric acid (9CI) has been explored by many scholars in the past, and the current Chen number method is as follows:
    First, diethyl malonate and halogenated hydrocarbons are started. First, under the action of basic reagents such as sodium alcohol, diethyl malonate generates carbon negative ions at its methylene. This carbon negative ion has good activity and can undergo nucleophilic substitution reaction with halogenated hydrocarbons to introduce the desired hydrocarbon group. Subsequently, through hydrolysis, decarboxylation and other steps, it is ingeniously converted into the target product 3-methyl-2-carbonylvaleric acid. In this process, the selection of halogenated hydrocarbons is quite critical, and it needs to be carefully determined according to the structure of the target product, and the reaction conditions also need to be carefully adjusted, such as temperature, amount of alkali, etc., in order to obtain the ideal yield.
    Second, ethyl acetoacetate can be started. Ethyl acetoacetate is also in an alkaline environment, methylene hydrogen is removed, and carbon negative ions are generated. Then it reacts with suitable halogenated hydrocarbons to achieve the introduction of hydrocarbon groups. Subsequent hydrolysis, acidification and heat decarboxylation can produce the target compound. In this way, the type and dosage of basic reagents, reaction time and other factors have a huge impact on the reaction process and product purity, so it is necessary to carefully grasp.
    Third, with the corresponding ketones and esters as raw materials, under the catalysis of strong bases, the Claisen condensation reaction occurs. By rationally designing the structure of the raw materials, the reaction is directed to produce an intermediate product containing the target structure. After appropriate treatment, such as hydrolysis, acidification and other steps, 3-methyl-2-carbonylvaleric acid can be obtained. In this method, the selection of strong bases and the control of the anhydrous and anaerobic conditions of the reaction system are the keys to ensure the smooth progress of the reaction.
    The above methods have their own advantages and disadvantages. In fact, they need to be selected according to the specific experimental conditions, the availability of raw materials and the requirements of product purity and yield.
    What are the precautions for 3-methyl-2-nitropyridine (9CI) during storage and transportation?
    9-Methyl-2-naphthyl ketone (9CI) has several precautions to be paid attention to during storage and transportation.
    The first is related to environmental conditions. This substance should be stored in a cool, dry and well-ventilated place. If the storage environment humidity is too high, or it causes moisture, it will affect the quality; if the temperature is too high, it may cause chemical reactions and even pose safety risks. For example, if placed in a high temperature and closed space, or due to internal reactions, heat accumulation, resulting in danger. When transporting, it is also necessary to ensure that the temperature and humidity of the transportation vehicle are suitable, and there is good ventilation to prevent the substance from being damaged due to uncontrolled temperature and humidity.
    The second is packaging. The packaging must be tight to prevent leakage. The packaging material should be able to withstand the chemical properties of the substance and not react with it. For example, use a special corrosion-resistant container with excellent sealing performance to avoid contact with outside air, moisture, etc. During transportation, due to vibration, collision and other factors, the packaging is easily damaged, so it is necessary to check the integrity of the packaging carefully before departure to ensure that the packaging is stable and free of leakage during the entire transportation process.
    The other is isolation. This substance should be stored and transported separately from oxidizing substances, acids, alkalis, etc. Due to its chemical properties, if it comes into contact with the above substances, it is very easy to have violent chemical reactions, which may cause serious consequences such as combustion and explosion. For example, if it coexists with strong oxidizing substances, under suitable conditions, or instantaneously initiates an oxidation reaction, releasing a large amount of energy.
    In addition, relevant safety procedures and standards must be strictly followed, whether it is storage or transportation. Staff need to be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. Storage and transportation vehicles should be equipped with corresponding fire and leakage emergency treatment equipment, so that in the event of an emergency, they can respond quickly and reduce losses and hazards.
    What are the effects of 3-methyl-2-nitropyridine (9CI) on the environment and human health?
    If the A gene and the B gene are transferred to it (9CI), the impact on the environment and human health is an important issue that needs to be investigated in detail today.
    The deletion or mutation of the A gene, or the disturbance of biochemical reactions in the body. In terms of the environment, if the A gene is widely mutated in an organism population, it may disrupt the ecological balance. If the A gene of a plant is abnormal, its absorption or transformation of specific nutrients is different from the normal, or it may cause disturbance to the nutrient cycle in the surrounding soil, affecting the survival of other organisms in the same area. And the substances controlled by the gene may be released into the environment and transmitted through the food chain, affecting a wider ecosystem.
    As for the B gene to it (9CI), it may be related to the human body's resistance to external evil and maintenance of internal environmental homeostasis. The human body is like a small universe. When the B gene is normal, it is like a guard strictly guarding various checkpoints to make the body operate in an orderly manner. If the B gene is abnormal, the immune system may be like an army of halberds, and the ability to resist pathogens will drop sharply, and people are prone to diseases. And the B gene may be related to the regulation of cell metabolism, and its abnormality or metabolic disorders may cause metabolic disorders, such as energy metabolism imbalance, people are prone to fatigue, obesity or weight loss, or it may involve organ functions. For example, the metabolic burden of the liver and kidneys will increase. Over time, organ functions will be impaired and diseases will multiply.
    The effects of these two on the environment and human health are complex and intertwined. Environmental changes can induce gene mutations, and gene states in turn affect biological adaptation to the environment. Therefore, in order to clarify the details, all kinds of research are needed, from the micro-genetic level to the macro-ecological environment, layer by layer analysis, in order to obtain the whole picture and seek well-being for the maintenance of the environment and human health.