Pyridine 3 Iodo 2 Trifluoromethyl
pyridine pyrrole pyrazine piperidine piperazine

pyridine, 3-iodo-2-(trifluoromethyl)-

    Specifications

    HS Code

    925214

    Chemical Formula C6H3F3IN
    Molecular Weight 299.00
    Appearance Solid (likely, based on similar compounds)
    Solubility In Water Low (due to non - polar fluorinated and iodo groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Vapor Pressure Low (due to its solid nature, typically)
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    Frequently Asked Questions

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    What are the chemical properties of 3-iodine-2- (trifluoromethyl) pyridine?
    The chemical properties of trialkyl methyl are particularly important. This group has a certain stability and exhibits unique properties in many chemical reactions.
    Looking at its electronic effect, trialkyl methyl is the power supply group, which can push the electron cloud towards the connected atoms or groups by means of induction and superconjugation effects. This property has a great impact on organic synthesis, which can change the charge distribution of molecules and cause the reactivity to change. For example, when trialkyl methyl is attached to the benzene ring, the electron cloud density of the benzene ring will increase, and in the electrophilic substitution reaction, the benzene ring is more susceptible to the attack of electrophilic reagents, and more inclined to adjacent and para-position substitution, because the electron cloud density of the power supply acting on the adjacent and para-position increases more significantly.
    Furthermore, trialkyl methyl has a considerable steric hindrance effect. Its volume is relatively large and occupies a certain space in the molecule. When there are other molecules or groups close to react with it, the steric hindrance will hinder or guide the reaction. For example, in some esterification reactions or nucleophilic substitution reactions, if there is trialkyl methyl near the check point of the reaction, due to space congestion, the proximity of the reaction reagent to the check point will be limited, thus affecting the reaction rate and product selectivity.
    In addition, trialkyl methyl is also reflected in the physical properties of the compound. Compounds containing this group may change their boiling point, melting point, solubility and other physical properties. Generally speaking, the introduction of trialkyl methyl can increase the non-polarity of the molecule, so that its solubility in non-polar solvents increases, and the solubility in polar solvents may decrease.
    From this perspective, the chemical properties of trialkyl methyl are complex and diverse, and it plays an important role in the synthesis of organic chemistry, the exploration of reaction mechanisms, and materials science, affecting the properties and reaction behaviors of many compounds.
    What are the physical properties of 3-iodine-2- (trifluoromethyl) pyridine?
    The physical properties of (triethyl) alkanes are characteristic, let me describe them.
    First of all, under the usual conditions, (triethyl) alkanes are mostly colored and transparent liquids, uniform to the ground, clear like jade, transparent to light, and refractive to the eye.
    The second time it boils, the (triethyl) alkane boils for a specific period. This property makes it appear physical in different conditions. When the temperature rises, when it boils, it melts from the liquid, the molecules are more active, and the beam of the liquid phase is free to move in the air.
    Furthermore, its melting is also fixed. When the temperature of the environment drops below the melting temperature, the (triethyl) alkane will solidify from the liquid, and the molecular arrangement will be orderly and dense from the phase to the phase, showing the shape of the solution.
    In terms of density, the (triethyl) alkane has a specific density value, and the normal matter such as water is either heavy or heavy, which affects its distribution in the mixing system. If the water is mixed, it is clear whether it is floating on the water or submerged under the water due to its density difference.
    Solubility is also an important physical property. ( Triethyl) alkane can be well dissolved in partially soluble water, just like water emulsion, molecular interaction makes it homogeneous dispersion; however, in water, the solubility is not good, and the two are miscible, which is due to the difference in molecular solubility.
    In addition, the viscosity of (triethyl) alkane also has its characteristics, which affects its flow performance. Under suitable conditions, the flow is like a babbling stream, which is natural; if the environment is changed, the viscosity may increase or increase, and the flow will also change.
    What are the common synthesis methods of 3-iodine-2- (trifluoromethyl) pyridine?
    The common synthesis methods of tribromoethyl group include the following:
    First, bromoethane can be obtained by adding ethylene and hydrogen bromide. The reaction conditions are mild and easy to operate. Under normal temperature and pressure, with the assistance of an appropriate catalyst, the two can react smoothly. The ethylene double bond is active and easy to undergo electrophilic addition with hydrogen bromide. Hydrogen and bromine atoms are added to the carbon at both ends of the double bond to produce bromoethane.
    Second, the reaction of ethanol with hydrobromic acid can also produce bromoethane. Under the action of appropriate temperature and catalyst, the ethanol hydroxyl group is replaced by bromine atoms. The reaction raw material is common and easy to obtain. During the reaction, hydrobromic acid provides bromine ions, which combine with hydroxyl groups in ethanol, and generate bromoethane and water through a series of reactions.
    Third, ethane is prepared by substituting ethane with bromine elemental substance under light conditions. Ethane undergoes radical substitution reaction with bromine elemental substance under light conditions. Bromine molecules are uniformly split into bromine radicals under light, attack ethane molecules, capture hydrogen atoms, and generate bromoethane and hydrogen bromide. However, this reaction has many side reactions and the product is complex, which needs to be carefully separated and purified.
    Fourth, acetylene is added with hydrogen bromide in steps. First, ethylene is added with one molecule of hydrogen bromide to obtain vinyl bromide, and then further with hydrogen bromide to generate bromoethane. This method can improve the selectivity of the product by controlling the reaction conditions and the ratio of the reactants, but the reaction steps are slightly more, and careful operation and control are required.
    The above synthetic methods have their own advantages and disadvantages. In practical applications, the most suitable method should be selected according to the comprehensive consideration of factors such as raw material availability, reaction conditions, product purity and cost.
    In which fields is 3-iodine-2- (trifluoromethyl) pyridine used?
    (Trimethylmethyl) This thing has its uses in all regions. In the process of controlling water, its achievements are not effective. In the three places, there are still floods. In the past, every flood season, floods were caused, and coastal fields and houses were often damaged, causing the people to suffer. (Trimethylmethyl) can be used to fix embankments, and its properties can make the embankment reach the flood, ensuring the safety of the people on one side.
    In addition, the navigation area is also indispensable. The three waterways are rough, and there are many reefs, so it is inconvenient for ships to travel. (Trimethylmethyl) can help improve the waterway, or fill in the recesses of the sea, or strengthen the walls of the waterway, so that the boat can travel, and promote the flow of coastal commerce.
    And in terms of water conservancy, (trimethylmethyl) also has great achievements. The construction of the three major areas, its help. The large area needs to withstand a huge amount of water, and the performance of the chemical construction materials, so that the large area can be fixed and constant, so that it can be efficient. It can send a huge amount of energy to the four sides, so as to improve people's livelihood and help workers, and promote the vigorous development of the society.
    In addition, in the irrigation area, (trimethyl) also has its use. The use of water from the three areas for irrigation can ensure the establishment of irrigation systems, repair channels, and ensure that the water in the canal is not leaking, and it can nourish the good fields, ensure the harvest of crops, and provide powerful support for the people's food. In addition, (trimethyl) plays an important role in water control, navigation, transportation, irrigation, and other fields, and is a rare good material.
    What are the storage conditions for 3-iodine-2- (trifluoromethyl) pyridine?
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