Pyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

pyridine-3-carboxylic acid

    Specifications

    HS Code

    939724

    Name pyridine - 3 - carboxylic acid
    Molecular Formula C6H5NO2
    Molar Mass 123.11 g/mol
    Appearance white to yellowish crystalline powder
    Odor characteristic
    Melting Point 136 - 139 °C
    Boiling Point 261 - 263 °C
    Solubility In Water soluble
    Pka 2.97
    Density 1.366 g/cm³

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    Frequently Asked Questions

    As a leading pyridine-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of pyridine-3-carboxylic acids?
    Borax is a chemical substance. Its chemical properties are unique and valuable to explore.
    The chemical composition of borax is sodium tetraborate, which is mostly colorless and translucent crystals or white powder at room temperature. This substance can be dissolved in water, and after dissolving, its aqueous solution will show a certain alkalinity.
    Borax has a variety of chemical properties. First, borax can react with acids. When it encounters strong acids, borax will react with it to form boric acid. The principle of this reaction is the replacement of strong acids with salts of weak acids. The acidity of boric acid is weaker than that of many common strong acids, so this reaction occurs. Second, borax will change significantly under heating conditions. After being heated, borax will gradually lose its crystalline water, and then decompose and react to form boron oxide and other substances. During this process, the morphology and chemical composition of the substance are changed. Third, borax can form complexes with some metal ions. Due to the structural characteristics of borax, it can combine with specific metal ions to form complexes with specific structures and properties. This property is used in chemical analysis and some material preparation fields.
    The chemical properties of borax make it useful in many fields. In industry, because it can interact with metal ions, it is often used as a flux for metal welding, which can effectively remove oxides from metal surfaces and make welding smoother. In the field of medicine, due to the alkalinity and some chemical properties of the aqueous solution, it has a certain disinfection and anti-corrosion effect. However, it should also be noted that if borax is used improperly, it will also have adverse effects on the human body and the environment. Therefore, when applying, it should be done with caution and follow the corresponding specifications and requirements.
    What are the common uses of pyridine-3-carboxylic acids?
    Ask him, what are the common uses of amino acids? Answer: Amino acids have a wide range of uses and play an important role in various fields.
    Let's talk about the field of medicine first. Many amino acids are essential for the human body and can be used to prepare amino acid infusions to supplement nutrition for people who cannot eat normally or need special nutritional support. Such as arginine, glutamate, etc., have the ability to treat hepatic coma and improve liver function. And some amino acids can be used as pharmaceutical raw materials to make medicines with special curative effects to treat diseases.
    In the food field. Amino acids can be used as food additives to enhance the flavor and nutritional value of food. For example, sodium glutamate is a common fresh taste agent, which can make dishes more delicious. There are also amino acids that can be used as nutrient enhancers and added to food to meet the nutritional needs of different groups of people. For example, adding lysine to children's food can promote children's growth and development.
    Industrial fields are also indispensable. In the fermentation industry, amino acids can be used to produce monosodium glutamate, citric acid and other products. In the leather industry, amino acids can be used as tanning agents for leather to make leather softer and more durable. In the textile industry, amino acids can be used for fabric finishing, making fabrics anti-wrinkle and antibacterial.
    In the agricultural field, amino acids are also very useful. Amino acid fertilizers can provide plants with nitrogen and other nutrients, enhance plant resistance, and improve crop yield and quality. And amino acids can be used as plant growth regulators to regulate plant growth and development. In summary, amino acids play an important role in many fields such as medicine, food, industry, agriculture, etc. They are widely used and have a profound impact on human life and production.
    What are the synthesis methods of pyridine-3-carboxylic acid?
    To make -3-pentenoic acid, there are three methods.
    First, use the diethyl malonate method. Diethyl malonate and halogenated hydrocarbons are nucleophilically substituted, and then alkaline hydrolysis and acidification decarboxylation can be obtained. If diethyl malonate and 1-bromopropene are subjected to nucleophilic substitution under the action of sodium alcohol, this step is based on the fact that diethyl malonate methylene hydrogen has a certain acidity. Sodium alcohol removes hydrogen to generate carbon anions, which are then replaced with the carbon where the halogen atom of the halogenated hydrocarbon is located. Then the product is hydrolyzed under alkaline conditions to generate corresponding carboxylates, and then acidified to decarboxylate to obtain -3-pentenoic acid. This method has mild conditions and good selectivity, but the price of the raw material diethyl malonate is slightly higher, and the steps are slightly complicated.
    Second, the Grignard reagent method is used. First, the Grignard reagent is prepared from bromoethylene, that is, the bromoethylene reacts with magnesium chips in anhydrous ether to form the Grignard reagent. Then it reacts with propionaldehyde. The carbon-magnesium bond of the Grignard reagent has strong nucleophilicity, attacking the carbonyl carbon of propionaldehyde to generate alcohol. Then the obtained alcohol is oxidized to acid, and a suitable oxidizing agent can be selected, such as Jones reagent. This route is common, but the Grignard reagent requires strict reaction conditions and requires an anhydrous and oxygen-free environment.
    Third, Propionaldehyde is reacted with suitable phosphorus ylide. Phosphorus ylide can be prepared from triphenylphosphine and halogenated hydrocarbons, and then formed by alkali treatment. This reaction can efficiently build carbon-carbon double bonds to generate -3-pentenoic acid. This method reacts quickly and has a high yield. However, triphenylphosphine is expensive, and it is troublesome to separate triphenylphosphine oxygenate during post-reaction treatment.
    What are the differences in the application of pyridine-3-carboxylic acids in different fields?
    What I am asking you is to inquire about the differences in the application of its - 3 - carboxylic acid in different fields. This is an interesting topic, let me explain it in detail for you.
    In the field of medicine, its - 3 - carboxylic acid may have unique effects. Physicians often rely on various drugs to cure diseases and save people. This carboxylic acid may participate in the regulation of human physiological and biochemical processes due to its special chemical structure. For example, it can assist in the delivery of drugs, so that the drug power can accurately reach the focus of the disease and improve the therapeutic effect; or it can be used as a key intermediate in drug synthesis. After ingenious chemical transformation, it can be made into a good medicine for specific diseases and used to cure chronic diseases.
    As for the food field, the use of - 3 - carboxylic acid is also different. In the field of food additives, it may play a role in preserving freshness and taste. It can delay the deterioration of food, maintain its delicious taste and good texture, so that people can enjoy long-term preservation and flavor. Or make a difference in the improvement of food flavor, add a touch of unique flavor, improve the taste and quality of food, and satisfy everyone's taste buds.
    In the chemical industry, the application of - 3 - carboxylic acid should not be underestimated. Chemical production pursues high efficiency and innovation, and this carboxylic acid may be used as a raw material for synthesizing special polymer materials. Through polymerization and other processes, materials with excellent performance can be obtained, or with good flexibility and corrosion resistance, which are widely used in packaging, building materials and many other aspects to promote the development and progress of the chemical industry.
    In the agricultural field, its -3-carboxylic acid may help the cause of agricultural mulberry. Or it can be used as a plant growth regulator to regulate the growth and development of crops, promote their thriving growth, and improve crop yield and quality; or it can play a role in pest control. With natural characteristics, it helps green agricultural production and protects the harvest of farmland.
    In summary, the application of 3-carboxylic acids in different fields, due to the characteristics and needs of each field, has shown a variety of diverse and significantly different applications, all of which are important elements to promote the development of various fields.
    What are the market prospects for pyridine-3-carboxylic acids?
    I look at the market prospect of 3-hydroxybutyric acid today, and its potential is quite impressive. At this time, the way of health is becoming more and more important to the world, and the wind of health is prevailing. 3-hydroxybutyric acid is gradually emerging in the field of health and wellness.
    Gein-3-hydroxybutyric acid can help human metabolism, promote energy conversion, and make the body healthy and energetic. For fitness people, it can increase muscle and reduce fat, and help them shape an ideal body shape, so it is favored by the fitness market. Fitness people all hope to improve the effect of exercise, so the demand for 3-hydroxybutyric acid is increasing.
    And in the context of medical treatment, it also has potential. Researchers have gradually discovered that 3-hydroxybutyric acid can be used to treat certain metabolic diseases, such as diabetes-related diseases. Doctors want to explore its benefits to help patients recover, which is also a big opportunity for market development.
    Furthermore, with the advance of science and technology, the preparation of 3-hydroxybutyric acid has become more convenient and the cost has declined. In the past, it was difficult to popularize because of its difficult production and high price. Today, it is not the case. With the goodness of the craftsmanship, the output has gradually increased, and the price is also close to the people, so it can enter the homes of ordinary people. The door to the market is gradually widening, and the audience is gradually widening.
    Watching the business situation of the husband, all merchants have seen this business opportunity and have joined it one after another. There are many marketing methods, and advertisements are all over the Internet and media, so that the public's awareness of 3-hydroxybutyric acid has gradually deepened. In the market, such as the rise of a new star, although it is not extremely prosperous, it will gradually shine. Over time, it will surely shine, and it will occupy an important seat in the health industry, with a bright future.