Pyridine 3 Carboximidamide Hydrochloride 1 1
pyridine pyrrole pyrazine piperidine piperazine

pyridine-3-carboximidamide hydrochloride (1:1)

    Specifications

    HS Code

    315893

    Name pyridine-3-carboximidamide hydrochloride (1:1)
    Chemical Formula C6H8ClN3
    Molar Mass 157.60 g/mol
    Appearance Solid (usually powder)
    Physical State At Room Temp Solid
    Solubility In Water Soluble
    Melting Point ~240 - 245 °C (decomposes)
    Odor Odorless (usually)
    Ph In Solution Acidic due to hydrochloride
    Pka Related to pyridine and imidamide groups
    Crystal Structure Determined by X - ray crystallography

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    Frequently Asked Questions

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    What are the chemical properties of pyridine-3-formamidine hydrochloride (1:1)?
    Among the three, methyl ether succinic anhydride (1:1) is a genus of organic compounds. This compound has unique chemical properties and can be investigated.
    Looking at its chemistry, the methyl ether succinic anhydride (1:1) has the general nature of acid anhydride. The acid anhydride is easy to hydrolyze in contact with water and form the corresponding acid. Methyl ether succinic anhydride (1:1) meets water and also hydrolyzes to produce methyl ether succinic acid. This hydrolysis process is the mechanism of nucleophilic addition-elimination. The hydroxyl group of water, the carbonyl carbon that nucleophilic attacks the acid anhydride, forms a tetrahedral intermediate, and then eliminates a leaving group, and then obtains methyl ether succinic acid. < Br >
    And because its structure contains methoxy groups, it has a certain lipophilicity. In organic solvents, it is more soluble. And this lipophilicity makes it a reagent for specific reactions in the field of organic synthesis. In the esterification reaction, it can interact with alcohols and form corresponding esters through appropriate catalysis. In this process, the carbonyl group of the anhydride is attacked by the hydroxyl nucleophilic group of the alcohol and converted into an ester product through an intermediate.
    And it has a certain reactivity. Under alkaline conditions, the reactivity is particularly obvious. Bases can promote the ring opening of acid anhydrides, leading to a variety of reaction pathways. Or react with nucleophiles such as amines to form amides. In this reaction, the nucleophilic nitrogen atom of the amine attacks the anhydride carbonyl group, and goes through similar nucleophilic addition-elimination steps to obtain an amide product.
    Methyl ether succinic anhydride (1:1) has important location and potential application value in the field of organic synthetic chemistry due to its acid-anhydride commonality, lipophilicity caused by methoxy group and reactivity under specific conditions. It can be used as a key reagent for various organic synthesis reactions, paving the way for the creation of new organic compounds.
    In which fields is pyridine-3-formamidine hydrochloride (1:1) used?
    "Tiangong Kaiwu" has a saying: "Is it used in various fields?"
    Methyl ether succinic anhydride (1:1) is used in the field of medicine and is often a key intermediate in organic synthesis. It can participate in the construction of active pharmaceutical ingredients through a specific reaction path. Due to its unique chemical structure, it can endow drugs with better solubility, stability or targeting. In the development of new antiviral drugs, this material can be used as a starting material through multi-step reactions to produce compounds with high antiviral activity, helping to overcome the problem of viral infection.
    In the field of materials science, it also has important uses. In the preparation of polymer materials, the introduction of methyl ether succinic anhydride (1:1) can change the physical and chemical properties of the material. If polyester materials are prepared, appropriate addition of this material can improve the flexibility and thermal stability of polyester. Plastic products made from this polyester can maintain good physical properties in different environments and are not easy to crack. They are widely used in packaging, building materials and other industries.
    Furthermore, in the field of fragrance industry, methyl ether succinic anhydride (1:1) can be used as an intermediary for fragrance synthesis. After a series of chemical reactions, it is converted into a compound with a unique aroma. The prepared fragrance has a rich and long-lasting aroma. It can be used in perfumes, air fresheners and other products to improve the aroma quality of products and meet consumers' diverse needs for aroma.
    It can be seen that methyl ether succinic anhydride (1:1) has outstanding applications in various fields such as medicine, materials science, and fragrance industry, providing assistance for the development of various industries.
    What are the synthesis methods of pyridine-3-formamidine hydrochloride (1:1)?
    To prepare -3-methoxybenzaldehyde (1:1), there are several ways to synthesize it.
    First, methoxybenzene and N-formyl morpholine can be used under the catalysis of anhydrous aluminum trichloride. This reaction needs to be carried out in a low temperature and anhydrous environment. The benzene ring of methoxybenzene is more susceptible to attack by electrophilic reagents due to the electron-giving effect of methoxy group. N-formyl morpholine generates electrophilic formyl positive ions under the action of aluminum trichloride, and then replaces with methoxybenzene to obtain -3-methoxybenzaldehyde. After the reaction is completed, a pure product can be obtained after various post-processing operations such as hydrolysis, extraction, and distillation.
    Second, 3-methoxybenzoic acid is used as the starting material. First reduce it to -3-methoxybenzyl alcohol, and a strong reducing agent such as lithium aluminum hydride can be selected. This reaction is violent and requires careful operation. Under low temperature and no water conditions, the hydrogen anion in lithium aluminum hydride attacks the carboxyl carbonyl carbon and reduces it to an alcoholic hydroxyl group. Then, with a mild oxidizing agent such as manganese dioxide, 3-methoxybenzyl alcohol is oxidized to -3-methoxybenzaldehyde. This oxidation process needs to control the reaction conditions to avoid excessive oxidation.
    Third, it can be obtained by hydrolysis of -3-methoxybenzonitrile. -3-methoxybenzonitrile is hydrolyzed first under acidic or alkaline conditions. Under acidic conditions, the nitrile group is protonated first, and then water attacks, generating amides through a series of reactions, and then further hydrolyzed to carboxylic acids. If the reaction conditions are controlled mildly, the reaction can stop at the aldehyde stage; under alkaline conditions, hydroxide attacks the nitrile group, and the process is similar. The hydrolysis products are acidified, separated and purified to obtain -3-methoxybenzaldehyde.
    All these methods have their own advantages and disadvantages, depending on the actual situation, such as the availability of raw materials, cost, and product purity requirements, etc.
    What is the market price of pyridine-3-formamidine hydrochloride (1:1)?
    I look at your question, and I am inquiring about the market price of Xiangqi -3-methyl ether succinic anhydride (1:1). The meaning of "Xiangqi -3" may need more background to be clear, but when it comes to methyl ether succinic anhydride (1:1), its price often varies due to various factors.
    First, the price of raw materials has an impact. The production of methyl ether succinic anhydride depends on the relevant raw materials. If the production of raw materials is subject to changes in time, geography, and supply and demand, the price will also change. If the raw materials are abundant, the price may decrease, and the price of raw materials may rise.
    Second, the preparation method is related to the cost. Different production methods have different difficulties, energy consumption, and yield. If a new method of high efficiency and low consumption is created, the cost may be reduced and the price may also be reduced; if the old method is still used, the cost will be high and the price will be difficult to reduce.
    Furthermore, the supply and demand of the market is essential. If the demand for methyl ether succinic anhydride (1:1) is strong in many industries, but the production and supply are insufficient, the price will rise; if the demand is weak and the production and supply have been supplied, the price will go down.
    Also, the difference between quality and price affects the price. High quality products have few impurities and excellent performance. They are more popular in areas with strict quality requirements such as fine chemicals, and their price is also higher than that of ordinary products.
    As for the exact market price, it is difficult to hide it. Or you need to consult the chemical raw material trading market, relevant manufacturers, industry intermediaries, and even consult the recent market survey report to get a more accurate price. However, the market conditions change, the price also moves, and you must pay attention in real time to know the current market.
    What are the storage conditions for pyridine-3-formamidine hydrochloride (1:1)?
    The storage conditions of triethylmalonic anhydride (1:1) are stored in a cool, dry and well-ventilated place. This material is delicate and sensitive to the environment, so it needs to be properly placed.
    First, the temperature needs to be strictly controlled. It is suitable for between 15 ° C and 25 ° C. If the temperature is too high, it is easy to change its activity or cause adverse reactions such as decomposition; if the temperature is too low, it may also affect its structure and performance, causing quality damage.
    Second, humidity is also crucial. The ambient humidity should be maintained between 40% and 60%. If the humidity is too high, water vapor is easy to come into contact with it, or cause adverse reactions such as hydrolysis, destroying its chemical structure; if the humidity is too low, although there is no worry about water vapor, it may make the substance too dry, which also affects its stability.
    Third, the storage place must be kept away from fire sources, heat sources and oxidants. Because of its certain chemical activity, in case of fire sources, heat sources, or the risk of combustion and explosion; in contact with oxidants, it is prone to violent chemical reactions, endangering safety.
    Fourth, it should be sealed and stored. This can prevent it from coming into contact with oxygen, water vapor and other components in the air, and ensure the stability of its own chemical properties. And the container should be made of suitable materials, such as glass or specific plastic materials, which can ensure sealing and do not chemically react with the substance.
    In this way, triethylene malonic anhydride (1:1) must be properly stored to maintain its quality and characteristics for subsequent use.