pyridine-3-carbohydrazide

Pyridine-3-formylhydrazide is a kind of organic compound. Its shape is mostly white to pale yellow crystalline powder, which is quite stable at room temperature and pressure.
This compound has many remarkable chemical properties. In terms of solubility, it is slightly soluble in water, but easily soluble in organic solvents such as ethanol and dichloromethane. In terms of reactivity, its molecule contains hydrazide groups (-CONHNH ²) and pyridine rings, which give it rich chemical reaction possibilities.
The hydrazide group has high activity and can react with many carbonyl compounds to form hydrazone derivatives. This reaction is widely used in the field of organic synthesis, and is often used to construct new organic molecular structures or to prepare materials with specific functions. At the same time, hydrazide groups can also participate in redox reactions, exhibiting unique electron transfer properties.
The presence of the pyridine ring also has a profound impact on the properties of the compound. The pyridine ring is alkaline and can react with acids to form salts. Moreover, the nitrogen atom on the pyridine ring can be used as an electron donor to participate in coordination chemical reactions and form complexes with metal ions. Such complexes have potential applications in catalysis, materials science and biomedicine.
In addition, pyridine-3-formylhydrazide has also shown some biological activity. Studies have shown that some compounds containing this structure have certain effects on specific biological targets, or can be used as lead compounds to provide ideas and directions for the development of new drugs.

Pyridine-3-formylhydrazide is an important compound in organic chemistry. Its common uses are quite extensive, let me tell them one by one.
In the field of medicinal chemistry, pyridine-3-formylhydrazide is often used as a key intermediate in drug synthesis. Due to its unique chemical structure, it can react with many other compounds to construct molecules with specific pharmacological activities. For example, when developing antibacterial drugs, it can be used to combine with specific groups to design new drugs that have inhibitory effects on pathogenic bacteria. Many studies have shown that compounds containing this structure exhibit good inhibitory activity against some bacteria and fungi, and may provide ideas for the development of new antibacterial drugs.
In the field of materials science, pyridine-3-formylhydrazide also has wonderful uses. In the preparation of some functional materials, it can be used as a modifier. It can interact with the surface of the material and change the surface properties of the material. For example, in the preparation of polymer materials, the addition of pyridine-3-formylhydrazide can enhance the adsorption capacity of the material to specific substances, or improve the hydrophilicity and stability of the material, making it have potential applications in adsorption separation, catalytic support and other fields.
In addition, in analytical chemistry, pyridine-3-formylhydrazide can be used as an analytical reagent. Because it can react specifically with certain metal ions to form complexes with specific colors or properties, the qualitative and quantitative analysis of metal ions can be realized. By observing the reaction phenomenon or measuring the relevant physical and chemical parameters, the content of metal ions in samples can be accurately determined, which is of great significance in the fields of environmental monitoring and food testing.
In summary, pyridine-3-formylhydrazide has important uses in many fields such as medicine, materials, and analysis, providing a powerful tool and foundation for research and development in various fields.

The synthesis of pyridine-3-formyl hydrazide is an important task in chemical preparation. The method often follows several paths.
First, pyridine-3-formyl acid can be used. First, pyridine-3-formyl acid is heated with thionyl chloride to form an acid chloride. In this process, the two are mixed in an appropriate proportion, and at a suitable temperature, an acid chloride is formed. The reaction formula is roughly as follows: pyridine-3-formyl acid + thionyl chloride → pyridine-3-formyl chloride + sulfur dioxide + hydrogen chloride. The resulting pyridine-3-formyl chloride is reacted with hydrazine hydrate, and the reaction conditions, such as temperature and the proportion of reactants, are controlled to obtain pyridine-3-formyl hydrazide. This reaction is mild, but the operation needs to be careful to prevent hydrolysis of acid chloride.
Second, pyridine-3-formate ethyl ester can also be used as a raw material. Pyridine-3-formate ethyl ester is co-placed with hydrazine hydrate in a solvent, a common solvent such as ethanol, and heated to reflux. In this reaction, the ester group undergoes an aminolysis reaction with hydrazine, and is gradually converted to hydrazide. The reaction is roughly as follows: ethyl pyridine-3-formate + hydrazine hydrate → pyridine-3-formyl hydrazide + ethanol. After the reaction is completed, the pure pyridine-3-formyl hydrazide can be obtained by separation and purification methods, such as recrystallization, column chromatography, etc.
Or other derivatives containing pyridine-3-formyl are used as starting materials, and the purpose of synthesizing pyridine-3-formyl hydrazide is achieved through a series of reactions. However, all methods require detailed study of reaction conditions, control of temperature, time, and proportion of reactants, and attention to separation and purification, in order to obtain high-purity pyridine-3-formylhydrazide for scientific research, industry, and other uses.

Pyridine-3-formylhydrazide is widely used in various fields such as medicine, pesticides, and materials science.
In the field of medicine, it is a key intermediate for the synthesis of many biologically active compounds. Due to the hydrazine group and pyridine ring contained in the structure, the compound has unique properties and can interact with specific targets in organisms. Taking the development of anti-cancer drugs as an example, researchers have modified the structure of pyridine-3-formylhydrazide to synthesize a series of derivatives. After experimental investigation, some derivatives have shown significant inhibitory effects on the growth of cancer cells. And in the field of antibacterial drugs, studies have also shown that compounds containing this structure have inhibitory activity against specific bacteria, or can become the lead compounds of new antibacterial drugs.
In the field of pesticides, pyridine-3-formylhydrazide can be used to create new pesticides. Nowadays, there is an increasing demand for high-efficiency, low-toxicity and environmentally friendly pesticides, and the structural characteristics of this compound make it possible to develop such pesticides. For example, by designing and synthesizing pesticides containing pyridine-3-formylhydrazide structure, it may be able to produce high-efficiency killing effects on pests by virtue of its special action mechanism, while reducing the harm to the environment and non-target organisms.
In the field of materials science, pyridine-3-formylhydrazide can participate in the preparation of functional materials. Because of its containing groups, it can chemically react with other substances, thereby changing the properties of materials. For example, in the preparation of fluorescent materials, the introduction of pyridine-3-formylhydrazide structure may make the material have unique fluorescent properties, which may have application prospects in sensors, optical displays, etc.

The price of pyridine-3-formylhydrazide in the market is difficult to determine. The price of this product often changes for various reasons. The wide and narrow source of its production, the price of the material used, and the difficulty of making it are all variables that cause the price.
Looking at the past, the price of chemical products fluctuated with the supply and demand of the market, the regulations of current affairs, and the resistance of raw materials. If there are many producers and few people are seeking, the price may drop; if the raw material is rare and the craftsmanship is complicated, the price will rise.
If you want to know the exact price of pyridine-3-formylhydrazide, you should study the market conditions carefully. Ask the chemists, visit the shops, or you may get a price close to the real price. However, the market is not constant, and the price is not fixed, that is, the price you inquire about at a time is difficult to hold for a long time. Therefore, those who ask for a price should pay attention at the right time, so that they can see that it has become a good price. Although they want to determine the size of the market price, it is difficult to do so, and they must take into account the feelings of many parties and time.