Pyridine 3 4 Dicarboxylic Anhydride
pyridine pyrrole pyrazine piperidine piperazine

Pyridine-3,4-dicarboxylic anhydride

    Specifications

    HS Code

    862264

    Name Pyridine-3,4-dicarboxylic anhydride
    Chemical Formula C7H3NO3
    Molar Mass 149.104 g/mol
    Appearance White to off - white solid
    Melting Point 179 - 181 °C
    Boiling Point Decomposes
    Solubility In Water Reacts with water
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMF, DMSO
    Acidity Anhydride can react as an acid derivative
    Reactivity Reacts with nucleophiles such as amines, alcohols

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    Frequently Asked Questions

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    What are the chemical properties of Pyridine-3,4-dicarboxylic anhydride?
    Pyridine-3,4-dicarboxylic anhydride, this is an organic compound. It has unique chemical properties.
    Looking at its physical properties, under normal conditions, or as a solid state, it has a certain melting point. The value of this melting point varies according to its purity and environmental conditions. And it can have a certain solubility in specific organic solvents, but its solubility in water may be quite limited.
    When it comes to chemical properties, first, in this anhydride compound, the structure of the acid anhydride makes it highly reactive. When exposed to water, it is prone to hydrolysis to form pyridine-3,4-dicarboxylic acid. The rate of this hydrolysis reaction is affected by many factors such as temperature and pH. In an acidic environment, the hydrolysis rate may be slightly slower; in an alkaline environment, the hydrolysis reaction can be accelerated.
    Second, pyridine-3,4-dicarboxylic acid anhydride can undergo alcoholysis with alcohols to form corresponding ester compounds. In this reaction process, specific catalysts and suitable reaction conditions, such as temperature and reaction time, are required to make the reaction efficient.
    Third, due to the presence of pyridine rings, this compound has both aromatic-related reaction properties. Electrophilic substitution reactions can occur, and the substitution check point is mostly affected by the positioning effect of the original substituents on the pyridine ring. Under suitable reaction conditions, substituents such as halogen atoms and nitro groups can be introduced into the pyridine ring to expand the variety of its derived compounds.
    Fourth, pyridine-3,4-dicarboxylic anhydride can be used as an important organic synthesis intermediate, which is widely used in pharmaceutical chemistry, materials science and many other fields. In drug synthesis, through its reaction with other compounds, molecular structures with specific biological activities can be constructed; in material preparation, it can participate in the preparation of polymer materials with special properties.
    In conclusion, pyridine-3,4-dicarboxylic anhydride exhibits rich and diverse chemical properties due to its unique chemical structure, providing a broad space for research and application in organic synthesis and related fields.
    What are the synthesis methods of Pyridine-3,4-dicarboxylic anhydride?
    The synthesis method of pyridine-3,4-dicarboxylic acid anhydride has various paths to follow. First, pyridine-3,4-dicarboxylic acid can be obtained by dehydration reaction. Among them, commonly used dehydrating agents such as acetic anhydride, phosphorus pentoxide, etc. Taking acetic anhydride as an example, pyridine-3,4-dicarboxylic acid and an appropriate amount of acetic anhydride are co-placed in a reaction vessel, and heating prompts the reaction to occur. In this process, acetic anhydride interacts with carboxylic acid to capture the hydroxyl group in its carboxylic group and dehydrate it to form an acid anhydride. The reaction conditions need to be precisely controlled, and the temperature is usually in a moderate range. If it is too high or side reactions will breed,
    Furthermore, specific pyridine derivatives can also be used as starting materials and converted through a series of chemical reactions. For example, select a pyridine compound containing an appropriate substituent, first go through the functional group conversion reaction, introduce carboxyl-related groups, and then go through the dehydration step to achieve the synthesis of pyridine-3,4-dicarboxylic acid anhydride. The key to this path lies in the selectivity and yield of the early functional group conversion. The reaction sequence and conditions need to be cleverly designed to improve the production efficiency of the target product.
    Or the synthesis can be achieved by means of a catalytic reaction. Select a suitable catalyst to promote the conversion of the reactants to pyridine-3,4-dicarboxylic acid anhydride in a specific reaction system. Among them, the type and dosage of catalysts have a significant impact on the reaction. High-efficiency catalysts can reduce the activation energy of the reaction, accelerate the reaction process, and improve product selectivity and reduce unnecessary by-product formation.
    What are the applications of Pyridine-3,4-dicarboxylic anhydride?
    Pyridine-3,4-dicarboxylic anhydride has a wide range of uses. In the field of medicine, it can be used as a key intermediate to synthesize drugs with specific physiological activities. For example, when developing some anti-tumor drugs, pyridine-3,4-dicarboxylic anhydride participates in it, which plays an indispensable role in the molecular structure shaping and activity of drugs, and helps to improve the targeting and inhibitory effect of drugs on tumor cells.
    In the field of materials science, this substance also has important applications. Polymer materials with excellent properties can be prepared by virtue of their chemical properties. For example, by polymerizing with other monomers, polymers with special optical and electrical properties can be obtained, which show potential application value in optoelectronic materials, or functional materials for the manufacture of Light Emitting Diodes, solar cells and other devices.
    Furthermore, in the field of organic synthesis, pyridine-3,4-dicarboxylic anhydride is often used as a reaction reagent and structural unit. Due to its unique chemical structure, it can participate in a variety of organic reactions, such as nucleophilic substitution, cyclization reaction, etc., to construct various complex organic compounds, providing organic synthesis chemists with a wealth of synthesis strategies and methods to help synthesize organic molecules with novel structures and unique properties.
    What is the market price of Pyridine-3,4-dicarboxylic anhydride?
    I have not obtained the exact market price of pyridine-3,4-dicarboxylic anhydride. However, the price in the market often changes due to various reasons, such as differences in origin, quality, purchase volume, and the rise and fall of market conditions. If you want to know the detailed price, you can go to the firm selling chemical reagents, the market trading chemical raw materials, or the e-commerce platform for chemical products, and you will be able to get the current price. And negotiate with the merchant, if the quantity is large or there is a discount. Or you can refer to the price of past transactions, but it is for reference only. The actual price is subject to the current inquiry.
    What are the storage conditions for Pyridine-3,4-dicarboxylic anhydride?
    Pyridine-3,4-dicarboxylic anhydride is one of the chemical substances. Its storage conditions are crucial to its stability and quality.
    This pyridine-3,4-dicarboxylic anhydride should be stored in a cool and dry place. Because of the cool environment, its chemical reaction rate can be slowed down, so that the chemical properties of the substance are not prone to drastic changes. If it is placed in a high temperature place, it may cause its decomposition, polymerization and other reactions to accelerate, which will damage its original characteristics. A dry environment is also indispensable, because the substance may be hygroscopic. If it encounters water vapor or reacts with water, other substances will be formed, causing its purity to decrease.
    Furthermore, it needs to be stored in a well-ventilated place. Good ventilation can avoid the accumulation of volatile gas and reduce the risk of explosion and poisoning. And ventilation can maintain the fresh air in the storage space and reduce the possibility of contamination by external impurities.
    When storing, it should also be stored separately from oxidizing agents, acids, bases and other substances. These kinds of substances are chemically active. If they coexist with pyridine-3,4-dicarboxylic anhydride, they can easily cause violent chemical reactions, or cause serious consequences such as combustion and explosion.
    In addition, the choice of storage containers is also exquisite. Use well-sealed containers to prevent them from contacting with outside air, water vapor, etc. Containers made of commonly used glass or plastic materials must ensure that their materials do not react with the substance and can withstand certain pressure and temperature changes.
    Storage of pyridine-3,4-dicarboxylic anhydride must follow the principles of cool, dry and ventilated, properly select storage containers, and separate them from incompatible substances, so as to ensure their quality and safety.