Pyridine 3 4 Dicarboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

Pyridine-3,4-dicarboxylic acid

    Specifications

    HS Code

    132972

    Chemical Formula C7H5NO4
    Molar Mass 167.12 g/mol
    Appearance White to off - white solid
    Solubility In Water Slightly soluble
    Melting Point 268 - 270 °C
    Pka1 3.23
    Pka2 4.94
    Density 1.55 g/cm³
    Odor Odorless
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

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    What are the chemical properties of Pyridine-3,4-dicarboxylic acid?
    Pyridine-3,4-dicarboxylic acid is a kind of organic compound. It is acidic, and the carboxyl group in the molecule can release protons. This substance can neutralize and react with bases to produce corresponding salts and water. In the field of organic synthesis, it is often used as a key raw material, and a variety of nitrogen-containing heterocyclic compounds can be prepared by specific chemical reactions.
    Looking at its physical properties, at room temperature and pressure, pyridine-3,4-dicarboxylic acids are mostly solid and have a certain solubility in water, but the solubility in organic solvents may vary depending on the properties of the solvent. Its stability is quite high, and it may encounter strong oxidizing agents or undergo oxidation reactions to cause structural changes.
    Furthermore, the interaction between the pyridine ring and the carboxyl group in the pyridine-3,4-dicarboxylic acid molecule has a great influence on its chemical properties. The electron cloud distribution of the pyridine ring can slightly change the acidity of the carboxyl group; conversely, the carboxyl group also affects the reactivity of the pyridine ring. This interaction enables the compound to participate in many unique chemical reactions and has broad application prospects in many fields such as medicinal chemistry and materials science.
    What are the main uses of Pyridine-3,4-dicarboxylic acid?
    Pyridine-3,4-dicarboxylic acid has a wide range of uses. In the field of medicine, this is an important raw material. The synthesis of many drugs depends on it. It can be combined with other chemical substances through specific chemical reactions, so as to obtain drugs with therapeutic effects, or to help treat and prevent diseases.
    In the chemical industry, pyridine-3,4-dicarboxylic acid also plays a key role. It can be used to prepare special polymer materials. By polymerizing with other monomers, it imparts unique properties such as good stability and heat resistance, and is used in high-end material manufacturing.
    Furthermore, in scientific research, it is also a commonly used reagent. Scientists can use it to conduct various chemical experiments, explore new chemical reaction paths, study the properties of compounds, and contribute to the expansion of knowledge and technological progress in chemical disciplines.
    In addition, in the preparation of some catalysts, pyridine-3,4-dicarboxylic acids can be used as ligands to combine with metal ions to form complexes with specific catalytic activities, improving the efficiency and selectivity of catalytic reactions, and are used in many reaction processes such as organic synthesis.
    What are the preparation methods of Pyridine-3,4-dicarboxylic acid?
    There are several ways to prepare pyridine-3,4-dicarboxylic acid. The first is to use quinoline as the starting material, which can be obtained by oxidation steps. Under specific oxidation conditions, if the appropriate oxidant is used, and the reaction temperature, time and ratio of the reactants are controlled, the structure of quinoline can be converted to form pyridine-3,4-dicarboxylic acid. In this process, the choice of oxidant is very important, such as potassium permanganate, which has strong oxidation property and can effectively promote the oxidation of the ring structure of quinoline. However, the reaction conditions need to be precisely controlled, otherwise it is easy to cause side reactions such as excessive oxidation.
    The second method can be started from the corresponding pyridine derivative. Pyridine derivatives with suitable substituents are selected, and the structure of pyridine-3,4-dicarboxylic acid is gradually constructed through a series of organic reactions, such as substitution and oxidation. Such methods require in-depth understanding of the reactivity of pyridine derivatives, and planning a reasonable reaction route according to the characteristics of their substituents. Different substituents have an impact on the check point and rate of the reaction, so the reaction process needs to be carefully designed so that the reaction can proceed according to the expected direction and achieve the synthesis of the target product.
    In addition, there are also those who start with other nitrogen-containing heterocyclic compounds and convert to pyridine-3,4-dicarboxylic acids through multiple steps. This pathway often requires complex reaction sequences, including ring opening, ring closing, and functional group transformation. Careful operation is required at each step to ensure the purity and yield of the intermediate product before the final successful preparation of pyridine-3,4-dicarboxylic acid. These methods have their own advantages and disadvantages. In actual preparation, the optimal method is selected based on factors such as the availability of raw materials, cost, and purity requirements of the target product.
    Where is Pyridine-3,4-dicarboxylic acid used?
    Pyridine-3,4-dicarboxylic acid, this is a special organic compound that is useful in many fields.
    In the field of medicine, it can be used as a key intermediate. Gein-pyridine-3,4-dicarboxylic acid has a unique chemical structure and can be converted into a variety of biologically active compounds by means of organic synthesis. For example, it can derive drug molecules that have therapeutic effects on specific diseases. For example, for some inflammatory diseases, by ingeniously modifying its structure, it can develop anti-inflammatory drugs that can help the human body relieve inflammation and restore health.
    In the field of materials science, it also has extraordinary performance. Using this as a raw material can prepare materials with special functions. For example, by coordinating with metal ions, metal-organic framework (MOFs) materials can be formed. Such materials have a high specific surface area and a regular pore structure, which is effective in gas adsorption and separation. It can efficiently separate different components of mixed gases, such as capturing carbon dioxide from industrial waste gas, helping the environmental protection industry and reducing greenhouse gas emissions.
    Furthermore, in the field of agriculture, pyridine-3,4-dicarboxylic acid can be used to create new pesticides. After rational design, compounds with insecticidal and bactericidal activities can be synthesized and applied to crops, which can effectively resist the invasion of diseases and pests, ensure the growth of crops, improve crop yield and quality, and escort agricultural harvests.
    From this perspective, although pyridine-3,4-dicarboxylic acid is an organic compound, it plays an important role in many fields such as medicine, materials science, agriculture, etc., providing assistance for the development of various fields, and the prospect is quite broad.
    What is the market outlook for Pyridine-3,4-dicarboxylic acid?
    Pyridine-3,4-dicarboxylic acid has a promising future in today's chemical materials market. Due to its unique chemical properties, it has shown significant application value in many fields, which has attracted much attention.
    In the field of medicine, pyridine-3,4-dicarboxylic acid is a key intermediate, which is relied on by the synthesis of many drugs. With the vigorous development of the global pharmaceutical industry, the demand for it is also rising steadily. This is because in the process of many new drug development, specific chemical structures need to be constructed by this substance to achieve the desired pharmacological activity. For example, in the development of some anti-tumor and anti-infective drugs, pyridine-3,4-dicarboxylic acid plays an indispensable role.
    In the field of materials science, this substance has also emerged. It can be used to prepare high-performance polymer materials, such as some polymers with special optical and electrical properties. With the advancement of science and technology, the demand for high-performance materials in electronics, optics and other industries has surged. Pyridine-3,4-dicarboxylic acid is an important raw material for the preparation of such materials, and the market prospect is broad. For example, in the preparation of organic Light Emitting Diode (OLED) materials, it can optimize material properties, improve luminous efficiency and stability.
    Furthermore, in the field of agricultural chemistry, pyridine-3,4-dicarboxylic acid also has application potential. It can be used as a raw material for the synthesis of new pesticides, helping to develop high-efficiency, low-toxicity and environmentally friendly pesticides, in line with the current needs of sustainable agricultural development.
    However, its market development also faces challenges. On the one hand, the synthesis process needs to be further optimized. The current synthesis methods may have complicated steps, high costs, and low yields, limiting large-scale production and application. It is urgent to improve the synthesis process, improve production efficiency and reduce costs. On the other hand, market competition is also becoming fierce. With its market prospects gradually emerging, many enterprises and scientific research institutions are involved in related research and development and production. How to stand out from the competition requires enterprises to strengthen technological innovation, improve product quality and service.
    Overall, although pyridine-3,4-dicarboxylic acids face challenges, due to their important applications in medicine, materials, agriculture and other fields, coupled with the continued development of various industries, the future market prospects are still bright, and it is expected to achieve breakthroughs and expansion in more fields.