Pyridine 2 Fluoro 5 Nitro
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2-fluoro-5-nitro-

    Specifications

    HS Code

    160140

    Chemical Formula C5H3FN2O2
    Molar Mass 142.09 g/mol
    Appearance Solid (likely yellowish, but color may vary)
    Solubility In Water Poorly soluble (due to non - polar nature of pyridine ring and hydrophobic nitro and fluoro groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
    Vapor Pressure Low vapor pressure, being a solid at room temperature

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    General Information
    Where to Buy Pyridine, 2-fluoro-5-nitro- in China?
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    Frequently Asked Questions

    As a leading Pyridine, 2-fluoro-5-nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-fluoro-5-nitropyridine?
    2-%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E5%90%A1%E5%95%B6, the nature is strong and strong, calcined in the fire and the shape remains unchanged, in the case of strong acid and alkali is also difficult to erode, quite tenacious quality. Its hardness is comparable to gold stone, although the sharp blade is added to the body, it is also difficult to leave marks, but the texture is not stiff and dead, if you have a clever way to do it, it can also change the form and cast into various utensils.
    This substance is like a calm water at ordinary times, without showing mountain dew, but once it encounters a specific thing, it is like a flood dragon getting water, which is very active in an instant, and can be wonderfully transformed, or heat and light, or gas flow, which is breathtaking. It also has a faint light flickering in the dark, just like a dark night star, although the light is weak, it lasts for a long time, giving people a sense of mystery.
    In addition, its chemical activity is quite wonderful. It is not easy to combine with ordinary things, but also can be closely related to other things in some special situations. It is like choosing the good and making friends, not promiscuous and heavy. Under high temperatures, it may be able to blend with certain elements to give birth to brand new things, which have the strengths of both, or have extraordinary uses.
    And because of its unique nature, it can protect itself between water and fire, so it can be used as a protective material. In harsh environments, it can protect other things. In the field of chemistry, it is like a noble man hidden behind the scenes. Although it is not often seen in front of people, once it appears, it has the ability to turn things around and cause all kinds of changes. It is really a magical thing.
    What are the common uses of 2-fluoro-5-nitropyridine?
    2-Hydroxy-5-carboxylpyridine has many common uses. In the field of medicine, it is a key intermediate in the synthesis of many drugs. The group has unique chemical activity and structural characteristics, and can be linked to other molecules by chemical reactions to construct compounds with specific pharmacological activities. For example, a certain type of antibacterial drug, by introducing this structure, its antibacterial spectrum and antibacterial activity can be optimized, and its ability to inhibit and kill specific bacteria can be enhanced.
    In the field of materials science, it can be used to prepare functional polymer materials. It is connected to the polymer chain by chemical reaction to give the material unique properties, such as improving the hydrophilicity of the material and enhancing the adsorption capacity of the material to certain substances. For example, in the preparation of separation membrane materials, the introduction of this structure can improve the selective permeability of the membrane to specific ions or molecules, and has important applications in water purification, material separation and other fields.
    In organic synthetic chemistry, it is an important synthetic building block. Chemists can use it as a starting material to construct complex organic molecular structures through a series of organic reactions, such as substitution reactions, addition reactions, etc. Because its structure contains hydroxyl and carboxyl groups that are active functional groups, it can participate in a variety of reactions, providing a variety of possibilities for the synthesis of various organic compounds.
    In addition, in the field of analytical chemistry, it can be used as a chemical analytical reagent. By means of specific reactions with certain metal ions or compounds, products with specific colors or physical properties are generated to achieve qualitative or quantitative analysis of specific substances. Such as forming stable complexes with specific metal ions, the content of metal ions is determined by spectroscopic analysis and other means.
    What are the synthesis methods of 2-fluoro-5-nitropyridine?
    The synthesis method of 2-bromo-5-fluorobenzamide often follows the conventional thinking of organic synthesis, and various chemical reactions are used to achieve the goal. Here are several common methods.
    One is the method of using halogenated aromatics as the starting material. Halogenated benzene containing an appropriate substituent can be taken first, reacted with a brominating agent, introducing bromine atoms, and then treated with a fluorinating agent to introduce fluorine atoms. Then, through a series of reactions, such as interacting with an appropriate amidating agent, the amide group is constructed to obtain the target product. During this process, attention should be paid to the fine regulation of the reaction conditions to ensure the selectivity and yield of each step of the reaction. For example, during bromination, according to the positioning effect of the existing substituents on the benzene ring, the brominating reagents and reaction conditions should be reasonably selected to achieve the purpose of introducing bromine atoms at the desired position.
    Second, the coupling reaction with the help of metal catalysis. Such as Suzuki coupling reaction, Stille coupling reaction, etc. First prepare aryl boronic acid or its esters containing bromine and fluorine substituents, and couple with halogenated aromatics containing amide groups under the action of metal catalysts. The advantage of this method is that it can precisely construct carbon-carbon bonds and achieve efficient synthesis of complex molecules. However, the choice and dosage of metal catalysts, the type of reaction solvent and base, etc., all have a great impact on the reaction, and need to be carefully explored and optimized.
    Third, the functional group conversion method based on the parent of benzamide. First prepare benzamide, and then introduce bromine and fluorine atoms in turn through halogenation reaction. However, in this process, it is necessary to pay attention to the influence of benzamide groups on the halogenation reaction to avoid side reactions. For example, the selectivity of the reaction can be improved by appropriate protection group strategy.
    In conclusion, the synthesis of 2-bromo-5-fluorobenzamide requires comprehensive consideration of many factors such as the availability of starting materials, the difficulty of reaction conditions, yield and selectivity, and flexible selection of suitable synthesis paths.
    What should be paid attention to when storing and transporting 2-fluoro-5-nitropyridine?
    When storing and transporting 2-% river-5-carboxypentanone, the following aspects should be paid attention to.
    The first environment is suitable. The storage place should be a cool, dry and well-ventilated place. This substance is quite sensitive to temperature and humidity, and high temperature and humidity are easy to cause deterioration. If it is exposed to high temperature, or triggers a chemical reaction, causing its structure to change and impairing its efficacy; if the environment is humid, or the substance absorbs moisture, it will affect the purity and stability. If it is extremely hot in midsummer, if the warehouse does not have good cooling, it may cause the material properties to change; if it is humid in the rainy season, if there are no moisture-proof measures, or the water content of the substance exceeds the standard.
    The second point is the importance of packaging. The packaging must be tight, and it is Because 2-% river-5-carboxypentanone has certain volatility and corrosiveness, if the packaging is not strict, the volatilization will not only cause material loss, but also volatile gas or harmful to the environment and human body; its corrosive or erosive packaging, resulting in leakage. If the improper packaging material is selected, or it is corroded and perforated, it will cause danger. Therefore, the packaging material needs to be corrosion-resistant and well sealed, such as special glass containers or anti-corrosive plastic materials.
    When transporting, also need to be cautious. Avoid mixing with oxidizing, acid and alkali substances. Because of its active chemical properties, it can be mixed with oxidizing substances, or cause severe oxidation reactions, or even explosions; mixed with acid and alkali substances, or neutralization reactions occur, changing the properties. If it is placed in a transportation vehicle with a strong oxidant, there will be a slight bump and collision, or a big disaster. The transportation process should be smooth, and the packaging should be damaged due to vibration and impact.
    In short, 2-% River-5-carboxypentanone is critical in storage and transportation, from environmental selection, packaging control to transportation specifications, and every link needs to be strictly operated according to specifications to ensure its quality and safety.
    What are the effects of 2-fluoro-5-nitropyridine on the environment and the human body?
    2-%-5-carboxypentylamine, which is important in the environment and in human beings, is described below.
    In the environment, if it is discharged to the outside world, if it enters the water, it may dry up the physiological generation of aquatic organisms. The decomposition of this substance by microorganisms in water may lead to the dissolution of dissolved oxygen in water, which affects the survival of aquatic organisms such as water. If it is released in the environment, it may affect the degradation of the soil. In the soil, it may affect the soil microbial community, change the soil distribution and physicochemical properties, and cause the absorption of plant roots.
    In human beings, respiratory inhalation, or irritation of respiratory mucosa, cough, respiratory distress and other diseases. If it is connected to the skin, it may cause skin sensitivity, allergies, etc. Once it enters the human body, it may cause normal biochemical reactions in the process of substitution, or dry. For example, it may affect the activity of certain enzymes, the synthesis and decomposition of important enzymes, and its activity can be changed to cause substitution. Periodic exposure to this substance, or increase the health of certain diseases, such as the immune system, may make the body vulnerable to pathogens. It may also cause adverse effects of the body, shadow the spirit, cause pain, and reduce the strength of the body. Therefore, the environment of 2-%-5-carboxypentylamine has a significant impact on human health, and needs to be re-studied.