Pyridine 2 Fluoro 4 Methoxy 9ci
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2-fluoro-4-methoxy- (9CI)

    Specifications

    HS Code

    304298

    Chemical Formula C6H6FNO
    Molecular Weight 127.116 g/mol

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    General Information
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    Frequently Asked Questions

    As a leading Pyridine, 2-fluoro-4-methoxy- (9CI) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2-fluoro-4-methoxypyridine (9CI)?
    The chemical structure of 2-% alkenyl-4-methoxybenzaldehyde (9CI) is also worth studying. Among this compound, the "alkenyl" group is the hydrocarbon group part of the carbon-carbon double bond. This double bond gives it a certain chemical activity and can participate in many addition reactions. It is like a dragon getting water, and it shows its talents in the field of organic synthesis. The "methoxy group" is formed by the connection between methyl and oxygen groups. It is connected to the benzene ring, which has a significant impact on the electron cloud distribution of the benzene ring. The benzene ring has a unique conjugate system, which is like a stable fortress. The presence of methoxy groups seems to add a different scene on the fortress, changing the electron cloud density, and then affecting the activity and check point of the electrophilic substitution reaction on the benzene ring. As for the "benzaldehyde" part, the aldehyde group is its important functional group, and the aldehyde group is active in nature, and can undergo various reactions such as oxidation, reduction, and nucleophilic addition. For example, it can be oxidized to carboxyl groups when interacting with weak oxidants, just like it has a driving force for transformation. This 2-% alkene-4-methoxybenzaldehyde (9CI), which integrates alkenyl, methoxy, phenyl ring and aldehyde group structures, and each part interacts and coordinates, endowing the compound with unique physical and chemical properties. In many fields such as organic synthetic chemistry and pharmaceutical chemistry, it may be able to emit a unique light like a pearl, opening up a wide range of fields for related research and applications.
    What are the physical properties of 2-fluoro-4-methoxypyridine (9CI)?
    2-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 (9CI) is an organic compound with unique physical properties. Its properties are mostly liquid at room temperature, the appearance is transparent and colorless, or a little light yellow, the texture is uniform, there is no obvious particle impurities, the fluidity is good, and the touch is similar to water but slightly different.
    Looking at its solubility, it shows good affinity in organic solvents. Organic solvents such as ethanol, ether, and chloroform can be miscible with 2-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 (9CI) in any ratio. This characteristic is due to the adaptation of its molecular structure to the forces between organic solvent molecules, which is like a tenon-mortise fit. However, it is difficult to dissolve in water because its molecular polarity does not match the polarity of water molecules, like a square peg chisel, which is difficult to blend.
    When it comes to density, 2-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 (9CI) is slightly lighter than water. When it is dropped into water, it will float lightly on the water surface, and the boundaries between the two are clear, such as oil floating in water, which is caused by the difference in material density.
    Volatility is also one of the significant physical properties of this substance. At room temperature and pressure, 2-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 (9CI) has a certain degree of volatility. Placed in an open container, its mass can be observed to gradually decrease over time. It has a unique odor in the air. Although it is not pungent or unpleasant, it is also recognizable, which indicates that its molecules have a strong ability to break free from liquid bondage and enter the gas phase. In terms of boiling point, 2-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6 (9CI) boiling point is in a specific range. When heated under a specific pressure and reaches a certain temperature, the liquid is rapidly converted into a gas, and a large number of bubbles escape from the liquid. This temperature is the boiling point. The specific boiling point reflects the strength and characteristics of intermolecular forces.
    What are the main uses of 2-fluoro-4-methoxypyridine (9CI)?
    2-Hydroxy-4-methoxybenzaldehyde (9CI), this substance has a wide range of uses. In the field of medicine, it is a key intermediate in the synthesis of many drugs. For example, when synthesizing compounds with specific physiological activities, it can act as a starting material. With its unique chemical structure, through a series of chemical reactions, it can build the core structure of drug molecules and help develop various drugs for the treatment of cardiovascular diseases, nervous system diseases, etc.
    In the fragrance industry, 2-hydroxy- 4-methoxybenzaldehyde is often used as a fragrance preparation ingredient because of its unique aroma. It can give a different flavor to the fragrance, or add a floral undertone, or create a special atmosphere. It is widely used in perfumes, air fresheners, detergents and other products to improve its aroma quality and uniqueness.
    In the field of organic synthesis, it is an important building block for organic synthesis and participates in the construction of complex organic compounds. By virtue of its functional groups, through esterification, condensation, oxidation and other reactions, it is combined with other organic compounds to synthesize materials with special structures and properties, such as for the manufacture of high-performance plastics, coatings, etc., to provide key raw material support for the development of materials science.
    What are the methods for preparing 2-fluoro-4-methoxypyridine (9CI)?
    To prepare 2-alkyne-4-methoxybenzaldehyde (9CI), there are various methods.
    First, it can be obtained by oxidation of the corresponding alcohol compound. If an alcohol containing a specific structure is selected, it can be treated with a suitable oxidant. Common oxidants such as chromium trioxide-pyridine complexes, which can precisely oxidize alcohol hydroxyl groups to aldehyde groups under mild conditions, and have little effect on alkynyl groups and methoxy groups, so as to achieve the purpose of preparing the target product.
    Second, halogenated aromatics are used as starting materials. First, the halogenated aromatics are coupled with the alkynylation reagent to construct the alkynyl-aryl structure, and then the methoxy group is introduced. The introduction of methoxy groups can be reacted with suitable methoxylation reagents, such as sodium methoxide, in appropriate solvents and temperatures through nucleophilic substitution reactions. Subsequently, the specific positions on the aromatic ring are formylated. The Vilsmeier-Haack reagent composed of N, N-dimethylformamide and phosphorus oxychloride is commonly used for formylation reagents such as Vilsmeier-Haack reagent, which is composed of N, N-dimethylformamide and phosphorus oxychloride. After this series of reactions, 2-alkynyl-4-methoxybenzaldehyde can be obtained.
    Third, starting from compounds with similar structures, it is prepared by functional group transformation. For example, acetophenone compounds containing alkynyl groups and methoxy groups are first prepared, and then the ketone groups are converted into aldehyde groups. The improvement of Huang Minglong's reduction method can be used. Under alkaline conditions, the ketone groups are first reduced to methylene groups with hydrazine hydrate as reducing agent, and then the methylene groups are converted into aldehyde groups through selective oxidation, and finally the preparation of 2-alkynyl-4-methoxybenzaldehyde is realized.
    What are the precautions for storing and transporting 2-fluoro-4-methoxypyridine (9CI)?
    2-% Jing-4-methoxyphenyl (9CI), during storage and transportation, there are several things to pay attention to, which must not be ignored.
    First words storage, this substance should be placed in a cool and dry place, away from direct sunlight. Cover the energy of sunlight, or cause it to undergo photochemical reactions, damaging its chemical properties. And it should be well ventilated to prevent the accumulation of harmful gases and affect the quality of the substance. Temperature is also critical and should be controlled within a specific range to avoid changes in the properties of the substance due to high or low temperature. Too high temperature, or cause it to evaporate and decompose; too low temperature, or cause it to solidify and crystallize, are not conducive to its preservation.
    As for transportation, make sure to pack it tightly. Packaging materials must be shock-resistant and pressure-resistant to prevent package damage and material leakage due to collisions and bumps during transportation. And the means of transportation should also be clean and free of other chemical residues to avoid chemical reactions with them. During transportation, pay more attention to weather changes. In case of extreme weather such as rainstorm and high temperature, proper protection measures should be taken. In case of rainstorm, prevent the package from being soaked in water; in case of high temperature, when there are cooling measures, keep it at a suitable temperature.
    Furthermore, when handling, operators should be cautious, handle it with care, and must not act rashly. And appropriate protective equipment, such as gloves, goggles, etc., is required to avoid direct contact between substances and the human body and damage to human health.
    Therefore, when storing and transporting 2% Jing-4-methoxyphenyl (9CI), pay attention to the above to ensure its safety and integrity.