Pyridine 2 Chloromethyl 3 4 Dimethoxy 9ci
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2-(chloromethyl)-3,4-dimethoxy- (9CI)

    Specifications

    HS Code

    103080

    Chemical Formula C9H10ClNO2
    Molecular Weight 199.634 g/mol
    Physical State Variable (solid/liquid)

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    Frequently Asked Questions

    As a leading Pyridine, 2-(chloromethyl)-3,4-dimethoxy- (9CI) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2- (chloromethyl) -3,4-dimethoxypyridine (9CI)?
    2-% (cyanomethyl) -3,4-diethoxybenzaldehyde (9CI), this is an organic compound. Its chemical properties are unique and it is widely used in the field of organic synthesis.
    Let's talk about the properties of its aldehyde group first. The aldehyde group is a highly reactive functional group and can participate in many reactions. In oxidation reactions, the aldehyde group is easily oxidized to a carboxyl group. For example, by treating with common oxidants such as potassium permanganate and potassium dichromate, the aldehyde group in this compound can be converted into a carboxylic group to generate corresponding carboxylic acid derivatives. In reduction reactions, the aldehyde group can be reduced to a hydroxyl group. For example, by using reducing agents such as sodium borohydride and lithium aluminum hydride, products containing alcohol hydroxyl groups can be obtained.
    Furthermore, its cyanomethyl group also has unique reactivity. Cyanyl groups can be converted into carboxyl groups by hydrolysis reaction, and this process often needs to be carried out under the catalysis of acids or bases. Under acidic conditions, cyanyl groups are gradually hydrolyzed to form amides, and then further hydrolyzed to carboxylic acids; under basic conditions, the hydrolysis process is similar, but the reaction mechanism is slightly different. In addition, the carbon-nitrogen triple bond of cyanomethyl groups can participate in nucleophilic addition reactions, and many nucleophilic reagents, such as alcohols and amines, can react with them to form new carbon-nitrogen or carbon-oxygen bonds, thereby expanding the structure of the molecule.
    As for the diethoxy phenyl group, the ethoxy group is the power supply subgroup, which can produce electronic effects on the benzene ring, increasing the electron cloud density of the ben This property affects the electrophilic substitution reaction on the benzene ring. Compared with benzene, the benzene ring of this compound is more prone to electrophilic substitution, and the substitution check point is affected by the localization effect of ethoxy, which mostly occurs in the adjacent and para-position of the ethoxy group. For example, in the halogenation reaction, halogen atoms tend to replace the hydrogen atoms of the adjacent and para-position of the ethoxy group.
    In summary, 2% (cyanomethyl) -3,4-diethoxybenzaldehyde (9CI) exhibits rich chemical properties due to its aldehyde groups, cyanomethyl groups and diethoxyphenyl groups, providing many possibilities for organic synthesis. It has potential application value in the fields of medicinal chemistry and material chemistry.
    What are the common uses of 2- (chloromethyl) -3,4-dimethoxypyridine (9CI)?
    The common uses of 2-% (cyanomethyl) -3,4-diethoxybenzaldehyde (9CI) are mainly as follows:
    First, in the field of organic synthesis, this compound is often used as a key intermediate. In the construction process of many complex organic compounds, its special structure can introduce specific functional groups and structural fragments for subsequent reactions. For example, with the characteristics of cyanomethyl and diethoxybenzaldehyde, complex molecular frameworks with unique pharmacological activities or material properties can be constructed through a series of chemical reactions, such as nucleophilic substitution, condensation, etc. When synthesizing heterocyclic compounds with potential biological activities, 2% (cyanomethyl) -3,4-diethoxybenzaldehyde can be used as a starting material to form a heterocyclic structure with specific biological activities by reacting with reagents containing heteroatoms such as nitrogen and oxygen.
    Second, in the field of medicinal chemistry, due to its structural characteristics, it is very likely to derive compounds with medicinal value. Researchers can modify and optimize the structure of this compound, and explore its interaction with biological targets by means of the modification of cyanomethyl and diethoxybenzaldehyde parts, and then develop new drugs. For example, proper conversion of the cyano group or adjustment of the ethoxy group may change the lipophilicity, water solubility, and affinity with the target of the compound, thereby obtaining a lead compound with better efficacy.
    Third, in the field of materials science, it can be used to prepare materials with special optical and electrical properties. For example, by introducing it into the polymer system, the conjugation properties of benzaldehyde structure and the influence of cyano and ethoxy groups can be used to change the electron cloud distribution of the material, thereby regulating the luminescence and electrical conductivity of the material. For example, synthesized polymer materials containing this structure may be used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs), providing new material options for improving device performance.
    What are the synthesis methods of 2- (chloromethyl) -3,4-dimethoxypyridine (9CI)?
    To prepare 2 - (cyanomethyl) - 3,4 - diethoxybenzaldehyde (9CI), there are many synthesis methods, which are described in detail today.
    First, you can start from common benzaldehyde derivatives. First, benzaldehyde is introduced into the specific position of its benzene ring through a specific substitution reaction. This step requires careful selection of reaction conditions and reagents. For example, the introduction of ethoxy can be achieved by reacting benzaldehyde with a suitable halogenated ethane under alkali catalysis. Then, try to introduce cyanomethyl at another position. In this process, a nucleophilic substitution reaction can be used to react with a suitable halogenated hydrocarbon such as sodium cyanide to form a cyanogen methyl reagent, and then interact with a benzaldehyde derivative that already contains an ethoxy group to achieve the access of the cyanogen methyl group, and then obtain the target product.
    Second, a phenolic compound can also be used as a raw material. The phenolic hydroxyl group is first protected to prevent it from interfering in subsequent reactions. Subsequently, through a series of electrophilic substitution reactions, ethoxy and cyanogen methyl groups are successively introduced into the phenolic ring of the phenolic compound. The introduction of ethoxy groups can be reacted with phenolic compounds in an alkaline environment by means of halogenated ethane. After the introduction of ethoxy groups, cyanogen methyl groups are accessed by nucleophilic substitution methods similar to the above. Finally, the protective group of the phenolic hydroxyl group is removed, and the phenolic compound is converted into an aldehyde group through oxidation and other steps, so as to synthesize 2- (cyanomethyl) -3,4-diethoxy benzaldehyde.
    Third, it can also start from other compounds containing benzene rings and having modifiable groups. For example, some benzene ring compounds containing carboxyl groups first convert the carboxyl group into a suitable leaving group, and then react with reagents containing ethoxy group and cyanomethyl group to gradually construct the structure of the target molecule. The product can also be obtained after multi-step reaction. Each method has its own advantages and disadvantages, and it is necessary to carefully choose the appropriate synthesis path according to the actual situation, such as the availability of raw materials, the difficulty of reaction, and the high and low yield.
    What are the precautions for storage and transportation of 2- (chloromethyl) -3,4-dimethoxypyridine (9CI)?
    2-% (cyanomethyl) -3,4-diethoxybenzaldehyde (9CI) is an organic chemical. When storing and transporting, be sure to pay attention to the following things:
    One of them is storage conditions. This substance should be stored in a cool, dry and well-ventilated place, and should be strictly protected from direct sunlight. Because it may be sensitive to light and heat, it is easy to decompose or deteriorate due to heat and light, which will damage the quality and purity. And it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to the active chemical properties of this substance, contact with the above substances, or violent chemical reactions, can cause danger. At the same time, the storage area should be equipped with suitable containment materials to prevent leakage accidents, so that the leakage can be collected and treated in time.
    The second is related to transportation requirements. Before transportation, it is necessary to ensure that the packaging is complete and sealed. Packaging materials must be able to effectively resist vibration, collision and friction, and prevent material leakage caused by damage to the container. During transportation, follow relevant transportation regulations and standards, and choose appropriate means of transportation. If transported by road, the transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment. And when transported, keep away from fire and heat sources, avoid sudden braking and sharp turns during transportation, and maintain smooth driving. If it is transported by rail, it is necessary to go through transportation procedures according to regulations and comply with the transportation requirements of the railway department. Air transportation is generally limited because it may be classified as dangerous goods.
    The third is personnel protection. Whether it is storage management or transportation personnel, they should receive professional training to be familiar with the nature of the substance, hazards and emergency treatment methods. When operating, wear appropriate protective equipment, such as protective glasses, protective gloves, protective clothing, etc., to prevent the substance from coming into contact with the skin and eyes. In case of inadvertent contact, immediate measures should be taken according to emergency treatment procedures, such as rinsing with plenty of water and seeking medical treatment if necessary.
    What is the market price range for 2- (chloromethyl) -3,4-dimethoxypyridine (9CI)?
    I don't know what the price of the product you said "2 - (cyanomethyl) - 3,4 - diethoxybenzaldehyde (9CI) " is in the market. However, if you want to know the range of its market price, you should look at multiple ends.
    First, it depends on the purity of the substance. If the purity is high and there are few impurities, it is suitable for high-end experiments and fine chemical synthesis, and the price must be high; if the purity is slightly lower, it can only be used for ordinary industrial purposes, and the price may be slightly lower.
    Second, it is related to the cost of production. The price of raw materials, the difficulty of preparation, and the amount of energy consumption all affect its cost. If the raw materials are rare and difficult to find, the preparation process is complicated, the cost must be high, and the price is also high.
    Third, the supply and demand of the market is also the main reason. If there are many people who need this substance, but the output is limited and the supply is in short supply, the price will rise; if the market is saturated and the supply exceeds the demand, the price may drop.
    Fourth, the different manufacturers also lead to different prices. Well-known large factories have strict quality control of their products, excellent after-sales service, and the price may be higher than that of small factories.
    However, I do not know the details of this substance, and it is difficult to determine its market price range. To obtain an accurate price, you can consult chemical raw material suppliers, chemical product trading platforms, or relevant industry professionals to determine the approximate price range.