Pyridine 2 Chloro 4 Iodo 3 Trifluoromethyl
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2-chloro-4-iodo-3-(trifluoromethyl)-

    Specifications

    HS Code

    286944

    Chemical Formula C6H2ClF3IN
    Molecular Weight 317.44
    Appearance Solid (predicted)
    Boiling Point 225.7±40.0 °C at 760 mmHg (predicted)
    Melting Point N/A
    Density 2.055±0.06 g/cm3 at 20 °C (predicted)
    Vapor Pressure 0.03±0.44 mmHg at 25 °C (predicted)
    Logp 4.37 (predicted)
    Solubility Soluble in organic solvents like dichloromethane, chloroform (predicted)
    Flash Point 90.3±27.3 °C (predicted)

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    Frequently Asked Questions

    As a leading Pyridine, 2-chloro-4-iodo-3-(trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the specific meaning of the chemical name of this product?
    The chemical name of this product really contains profound meaning. In ancient Chinese, its chemical name is like the secret language of creation, hiding the universe.
    Chemical names are not random, they all have their origins and veins. Every word, every symbol, is the crystallization of matter that the wise men of all dynasties explored and analyzed in nature. Or they are arranged in order according to their constituent elements, such as gold, wood, water, fire, and earth, to indicate their inner components; or according to their unique properties, such as cold, heat, dryness, and wetness, to reveal their special functions.
    Or by analogy, the microscopic chemical substances are connected to the macroscopic world and all things. Just like taking heaven and earth as the blueprint, the microscopic substances also have the order and laws of heaven and earth. For example, the naming of certain substances, referenced by stars, seems to suggest a subtle connection with the universe; taking mountains and rivers as a metaphor, indicates that their characteristics echo the thick and agile characteristics of mountains and rivers.
    And chemical names also carry the inheritance of culture. In the civilization of China for thousands of years, the cognition and naming of substances are integrated into Confucian benevolence, righteousness, propriety, wisdom, and faith, Taoist natural inaction, and Buddhist causal cycle. Therefore, chemical names are not only a sign of matter, but also a manifestation of cultural inheritance and wisdom accumulation. With concise words, they convey rich information, opening the door for future generations to explore the material world, leading our generation to swim in the vast ocean of chemistry and explore the true meaning of all things.
    What are the main physical properties of 2-chloro-4-iodine-3- (trifluoromethyl) pyridine?
    (Triethylmethyl) amine is an organic compound. It has various important physical properties.
    First of all, its phase state and odor, under room temperature and pressure, (triethylmethyl) amine is liquid and emits a special odor. This odor is volatile, and people can sense it by smell. In a specific environment, its odor can cause air odor and affect the sensory experience of the environment.
    Second and its solubility, (triethylmethyl) amine can be partially dissolved in water. Due to its molecular structure, it contains polar groups and can interact with water molecules to form hydrogen bonds, etc. However, its hydrocarbon group part is hydrophobic, causing it to be incompletely soluble in water and only partially soluble. In organic solvents such as ethanol, ether, etc., (triethylmethyl) amine has good solubility. Due to the principle of similar phase dissolution, it can be miscibly miscible due to the appropriate intermolecular forces with organic solvents.
    Furthermore, in terms of its density, (triethylmethyl) amine has a slightly smaller density than water. When it is co-placed with water in a container, it can be seen that it floats on the water surface. This property is of great significance in experimental operations such as separation and extraction and industrial applications. It can be separated by density differences.
    The boiling point of (triethylmethyl) amine is moderate. This boiling point determines its phase transition at a specific temperature. When heated to the boiling point, (triethylmethyl) amine changes from liquid to gaseous state. The value of the boiling point depends on the setting of its storage, transportation and reaction conditions. For example, in operations such as distillation, the temperature should be controlled near the boiling point to achieve separation from other substances.
    In addition, (triethylmethyl) amines have certain volatility. Due to the non-extreme intermolecular force, some molecules are prone to obtain energy to escape the liquid surface and diffuse in the air. This volatility affects their storage and needs to be sealed for storage to prevent changes in their volatile content and impact on the environment.
    What are the common uses of 2-chloro-4-iodine-3- (trifluoromethyl) pyridine?
    The common uses of (triethylmethyl) amine include the following.
    First, in the field of organic synthesis, it is often used as a base. Because of its moderate alkalinity, it can capture protons in many reactions and promote the progress of the reaction. For example, in the esterification reaction, it can neutralize the generated acid and move the equilibrium in the direction of the product; in the nucleophilic substitution reaction, it can assist the substrate conversion and improve the reaction efficiency.
    Second, it also has important uses in the field of phase transfer catalysis. Because its molecular structure contains hydrophobic hydrocarbons and hydrophilic nitrogen atoms, it can promote the reactants to cross the two-phase interface that is incompatible with each other, making the reaction more prone to occur under mild conditions. Such as the reaction of halogenated hydrocarbons and sodium cyanide in the water-organic phase, (triethylmethyl) amine can help cyanyl negative ions enter the organic phase and speed up the reaction rate.
    Third, in pharmaceutical chemistry, it is often used as an intermediate in drug synthesis. Due to its alkalinity and specific spatial structure, it can participate in the construction of biologically active molecular structures. In the synthesis of some antibacterial drugs and cardiovascular drugs, (triethylmethyl) amines are used to introduce specific groups to optimize the activity and solubility of drugs.
    Fourth, in the field of materials science, it can be used to prepare materials with specific properties. For example, in the preparation of certain ion exchange resins, (triethylmethyl) amine can participate in the construction of the resin skeleton, endowing the resin with the ability to selectively adsorb specific ions; in polymer polymerization reactions, appropriate addition of (triethylmethyl) amine can adjust the reaction rate and polymer structure.
    What are the methods for preparing 2-chloro-4-iodine-3- (trifluoromethyl) pyridine?
    The preparation method of triethylamine has been known for a long time, and it is described in detail today.
    First, ethanol and ammonia are used as raw materials and obtained by catalytic reaction. The reaction of ethanol and ammonia is heated in a certain proportion in the presence of a catalyst. In this reaction, the hydroxyl group of ethanol is replaced by an amino group to gradually generate triethylamine. The reaction process is quite complicated, and the reaction conditions such as temperature, pressure, and catalyst dosage need to be carefully regulated. If the temperature is too high or too low, the reaction product can be impure and the yield of triethylamine can be affected.
    Second, the method of reacting halogenated ethane with ammonia. Take halogenated ethane, such as bromoethane or chloroethane, and react with ammonia in a suitable solvent. The nitrogen atom of ammonia nucleophilically attacks the carbon atom of halogenated ethane, and the halogen atom leaves to form triethylamine. This process also requires attention to the reaction conditions. The choice of solvent is crucial. It is necessary to choose those who can dissolve the reactants and do not have side reactions with the products. At the same time, the amount of halogenated ethane and the reaction time also have a significant impact on the formation of the product.
    Third, the preparation path using acetaldehyde as a raw material. Acetaldehyde first condenses with ammonia and is converted into triethylamine through a series of reactions. This approach requires multiple steps of reaction, and each step needs to be strictly controlled. Starting from the condensation reaction of acetaldehyde and ammonia, the subsequent conversion steps involve many organic chemical changes, such as hydrogenation, dehydration and other reactions. The conditions of each step and the treatment of intermediates are the keys to successful preparation.
    All these methods for preparing triethylamine have advantages and disadvantages. In practice, the appropriate method should be carefully selected according to the purity, yield and cost of the desired product.
    What are the precautions for using 2-chloro-4-iodine-3- (trifluoromethyl) pyridine?
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    The first to bear the brunt is its toxicity. This substance has a certain toxicity. When operating, be careful not to let it touch the skin, nor let it enter the eyes. If you accidentally touch it, rinse it with a lot of water immediately and seek medical treatment quickly. And during use, the space must be well ventilated to prevent inhalation of its volatile gas and damage to the body.
    Furthermore, its stability cannot be ignored. The properties of Sanxiang methyl may change due to external factors, such as temperature, humidity, etc. When storing, it should be placed in a cool, dry place, away from strong light, and away from fire and heat sources to prevent accidents. At the same time, it is necessary to pay attention to its reaction with other things, and do not mix with substances of unknown nature at will to avoid dangerous chemical reactions.
    Operating specifications are also key. Before use, the equipment used should be carefully checked to ensure that there is no risk of damage or leakage. When operating, strictly follow the established procedures, accurately control the dosage, reaction conditions, etc., and must not be changed arbitrarily. If there is a new method or process, it must be tested in a small area to confirm that it is safe and feasible before large-scale application.
    In addition, the record should not be slack. During use, key information such as dosage, reaction phenomenon, time, etc. should be recorded in detail for subsequent inquiry and analysis. If there is a problem, it can also be traced and investigated accordingly.
    In short, in the use of Sanxiang methyl, every step is related to safety and effectiveness, and must not be taken lightly.