Pyridine 2 Chloro 3 Fluoro 5 Methyl
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2-chloro-3-fluoro-5-methyl-

    Specifications

    HS Code

    212911

    Chemical Formula C6H5ClFN
    Molecular Weight 145.56

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    General Information
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    Frequently Asked Questions

    As a leading Pyridine, 2-chloro-3-fluoro-5-methyl- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-chloro-3-fluoro-5-methylpyridine?
    2 + -Deuterium-3 + -tritium-5 + -methylpyridine, which has a wide range of uses.
    In the field of pharmaceutical synthesis, it can be used as a key intermediate. Many drugs with specific therapeutic effects rely on 2 + -deuterium-3 + -tritium-5 + -methylpyridine to build the core structure during the synthesis process. Through organic synthesis, it is cleverly linked with other chemical groups to generate complex molecules with pharmacological activity to deal with various diseases.
    In the field of materials science, it also has important value. It can be used as a raw material for the preparation of materials with special properties. Due to its unique chemical structure, it can impart properties such as enhanced stability and changed conductivity to materials. For example, the introduction of this substance in the synthesis of some new polymer materials can optimize the mechanical properties and thermal stability of materials, making it suitable for applications in aerospace, electronic equipment and other fields that require strict material properties.
    In the fine chemical industry, 2 + -deuterium-3 + -tritium-5 + -methylpyridine is often used to prepare high value-added fine chemicals. For example, some special fragrances, dyes, etc., its participation in the synthesis can give products a unique smell or color, improve product quality and market competitiveness.
    In addition, in the field of organic catalysis, the substance may exhibit certain catalytic activity due to its own structural characteristics. It can catalyze specific organic reactions, improve reaction efficiency and selectivity, and help build more efficient and green organic synthesis pathways.
    What are the physical properties of 2-chloro-3-fluoro-5-methylpyridine
    2 + -Deuterium-3 + -tritium-5 + -methylnonane This material has special properties, its color is clear, and it is liquid at room temperature. Its light weight and density are smaller than that of water. It is placed on water, floating but not sinking.
    Looking at its phase state, it has good fluidity, like the water of a stream, smooth and smooth. Smell it, it has a special smell, although it is not pungent, it is also different from ordinary tasteless things.
    Furthermore, this substance has remarkable flammability. In case of open flames and hot topics, it is very easy to burn. When burned, the flame is bright and the temperature is quite high. This flammability makes it in the field of energy or has other uses, and can be used as fuel for combustion to release energy. < Br >
    Its solubility also has characteristics. It is soluble in many organic solvents, such as alcohols and ethers, which can be soluble with it and mixed into one. However, it is difficult to dissolve in water, and the two meet, each is a state, and they are distinct.
    And its stability, under normal conditions, is relatively stable, and can be stored for a long time without easy qualitative change. However, in case of special chemical reagents or extreme environments, it can also trigger chemical reactions, causing changes in its structure and properties.
    This is the approximate physical property of 2 + -deuterium-3 + -tritium-5 + -methylnonane, which is used in many fields such as chemical industry and scientific research, or because of these physical properties, it shows unique value.
    Is 2-chloro-3-fluoro-5-methylpyridine chemically stable?
    This is about the stability of the chemical properties of "2-deuterium-3-tritium-5-methylfuran".
    In this compound, deuterium and tritium are both isotopes of hydrogen. Compared with ordinary hydrogen, deuterium has more neutrons. When it forms bonds with atoms, due to mass differences, it will slightly affect the properties of the bonds, usually increasing the bond energy slightly, enhancing stability to a certain extent. Tritium is radioactive, and although it will change its properties due to decay, in a short time scale, if only the chemical stability is considered, its effect on the overall structure is similar to that of deuterium.
    The structure of methylfuran, the furan ring has a certain aromaticity, which endows the molecule with a certain stability. However, the connection of methyl groups on the ring will change the electron cloud density of the furan ring, which will also affect its stability.
    As for the overall "2-deuterium-3-tritium-5-methylfuran", its chemical properties are relatively stable under normal conditions without external severe conditions such as high temperature, strong acid and alkali, and strong oxidizing agents. However, due to the radioactive existence of tritium, in the long run and under special conditions, the structure and properties will be changed due to the decay of tritium. Overall, its stability is guaranteed in common chemical scenarios, but it is necessary to consider the potential impact of tritium, a special factor, on its long-term and under specific conditions.
    What are the preparation methods of 2-chloro-3-fluoro-5-methylpyridine
    To prepare 2-deuterium-3-bromo-5-methylpyridine, there are various methods.
    First, the corresponding pyridine derivative can be obtained by halogenation and isotope exchange. First, take a suitable pyridine parent, use a specific halogenating agent, such as a brominating agent, under suitable reaction conditions, such as in a suitable solvent, and control a certain temperature and time to selectively replace the bromine atom in the third position. Then, by isotope exchange reaction, deuterium atoms are introduced into the second position. This process requires fine regulation of reaction conditions to achieve ideal yield and selectivity.
    Second, using pyridine containing specific substituents as the starting material, the target molecule is constructed through multi-step reaction. First, the substituents on the pyridine ring are modified to have the activity check point of introducing bromine and deuterium atoms. For example, the methyl group is properly activated first, and then the bromine and deuterium atoms are introduced in sequence through nucleophilic substitution or electrophilic substitution reaction. Each step of the reaction needs to consider the influence of reactivity, selectivity and side reactions, and gradually approaches the target product through separation, purification and other steps.
    Third, the coupling reaction strategy of metal catalysis can be used. Using reagents containing bromine and deuterium atoms, the coupling of carbon-bromine bonds and carbon-deuterium bonds with pyridine derivatives is realized under the action of metal catalysts. Select suitable metal catalysts, such as palladium, nickel and other catalysts, and match specific ligands to optimize the pH, temperature and other conditions of the reaction system, so as to promote the efficient coupling reaction to obtain 2-deuterium-3-bromo-5-methyl pyridine. Each method has its own advantages and disadvantages, and the actual preparation needs to be weighed according to factors such as raw material availability, cost, yield and purity requirements.
    What are the precautions for storing and transporting 2-chloro-3-fluoro-5-methylpyridine?
    2 + -Deuterium-3 + -tritium-5 + -methylpyridine requires attention to many key matters during storage and transportation.
    This substance has unique properties and should be stored in a cool, dry and well-ventilated place. Because it may be extremely sensitive to temperature and humidity, improper control of temperature and humidity can easily cause chemical reactions and change its own properties. The warehouse must be kept away from fire and heat sources to prevent accidents such as fire or explosion. And it needs to be stored separately from oxidizing agents, acids, alkalis and other substances to avoid dangerous reactions caused by mutual contact.
    When transporting, it is also necessary to exercise caution. Transportation vehicles must have reliable fire and explosion-proof facilities to deal with emergencies. The loading and unloading process must be handled with care and must not be operated brutally to prevent the leakage of the substance due to damaged packaging. During transportation, pay close attention to road conditions and weather changes to avoid severe conditions such as high temperature and humidity. If the transportation route passes through densely populated areas, it should strictly abide by relevant regulations and take necessary protective measures to prevent leakage from posing a threat to public safety.
    In addition, whether it is storage or transportation, it is necessary to strictly follow relevant safety regulations and operating procedures. Operators need to undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident such as leakage, emergency plans should be quickly activated and effective leak plugging, cleaning and protection measures should be taken to minimize the harm.