Pyridine 2 Chloro 3 Fluoro 4 Trifluoromethyl
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2-chloro-3-fluoro-4-(trifluoromethyl)-

    Specifications

    HS Code

    358820

    Chemical Formula C6H2ClF4N
    Molecular Weight 199.53
    Appearance Typically a colorless to pale - yellow liquid (physical state can vary based on conditions)
    Boiling Point Data may vary, but in the range of 150 - 180 °C approximately (estimated based on similar compounds)
    Density Estimated around 1.4 - 1.6 g/cm³ (approximate, based on related halo - pyridine compounds)
    Solubility Soluble in organic solvents like dichloromethane, chloroform; limited solubility in water
    Vapor Pressure Relatively low vapor pressure at room temperature, but increases with temperature
    Flash Point Caution: Flammable, flash point in the range of 50 - 70 °C (estimated)

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    Frequently Asked Questions

    As a leading Pyridine, 2-chloro-3-fluoro-4-(trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of this product 2-chloro-3-fluoro-4- (trifluoromethyl) pyridine
    This substance is called 2-deuterium-3-ene-4- (trienomethyl) alkyne, and its main use is within the scope of "Tiangong Kaiwu", which can be discussed from the perspective of traditional processes and related applications.
    In ancient metallurgy, it may play a unique role. In the process of metal smelting, the requirements for heat and additives are strict. This substance may be able to adjust the reaction environment in the furnace by virtue of its characteristics. For example, in some casting processes that require precise control of temperature and reaction rate, its addition may change the atmosphere in the furnace and affect the purity and texture of the metal.
    Furthermore, ancient alchemy cannot be ignored. Alchemists pursue the medicine of longevity. In the complex pill furnace reaction, various substances interact. This substance may participate in the chemical reaction chain of alchemy due to its special structure, or serve as an auxiliary reactant to promote the occurrence of certain key reactions and help refine the so-called "magic pill".
    In the traditional printing and dyeing industry, there are also potential uses. Ancient printing and dyeing pays attention to the durability and uniqueness of color. The substance may be used as a mordant or special dye component to make the fabric color more uniform and firm, and give the fabric a unique color, satisfying the ancient people's pursuit of the beauty and quality of fabrics such as clothing.
    In addition, in the field of ancient weapon manufacturing, in order to improve the performance of weapons, such as hardness and toughness, the treatment of materials is extremely critical. This substance may be used in the material improvement process of weapon forging to enhance the quality and performance of weapons by fusing or reacting with metal materials to meet the needs of war and defense.
    What are the synthesis methods of 2-chloro-3-fluoro-4- (trifluoromethyl) pyridine
    To prepare 2-cyanogen-3-ene-4- (trienyl methyl) alkyne, there are many methods for its synthesis.
    First, the corresponding halogenated hydrocarbons and cyanide reagents can be nucleophilic substitution reaction, and the cyanide group can be introduced first. The halogen activity in halogenated hydrocarbons needs to be appropriate. The cyanide reagents such as potassium cyanide interact with each other under suitable solvents and conditions, and the halogen is replaced by a cyanide group. This is the basic step. Then, for the construction of alkenyl groups and alkynyl groups, the nucleophilic addition reaction of alkynes can be used. Select alkynes with suitable substituents, and under the action of catalysts, add electrophilic reagents containing alkenyl structures to introduce alkenyl and alkynyl moieties, and by controlling the reaction conditions and the ratio of reactants, ensure that the substitution position is accurate.
    Second, from the raw materials containing alkenyl and alkynyl groups, functional group protection can be carried out first. Protect the alkenyl or alkynyl groups with suitable protective groups to avoid their interference in subsequent reactions. After that, through nucleophilic substitution, condensation and other reactions, cyano and methyl and other substituents are introduced. After the introduction of the substituent is completed, the protective group is removed under mild conditions to restore the activity of the alkenyl and alkynyl groups, and the target product is obtained.
    Third, transition metal-catalyzed coupling reactions can be used. For example, a palladium catalytic system is used to couple cyanide-containing halides with organometallic reagents containing alkenyl groups, alkynyl groups, and methyl groups. In the reaction, palladium catalysts activate the reactants to promote the formation of carbon-carbon bonds, and to construct the target molecular structure with high selectivity. This method has relatively mild conditions, good yield and selectivity, but requires high reaction equipment and operation, and the cost of catalysts may affect industrial production.
    All synthesis methods have advantages and disadvantages. According to actual needs and conditions, the choice needs to be weighed and the reaction carefully regulated to obtain the target product efficiently.
    What is the market price of 2-chloro-3-fluoro-4- (trifluoromethyl) pyridine?
    There are many kinds of goods in the world, and their prices vary from time to time and from city to city. Today there is 2 + - 3 - Jiang - 4 - (Sanjiang methyl). If you want to know the price of this product in the market, it is an important matter.
    However, the price is determined, not overnight, and it depends on many reasons. First, it is about its quality. Those who are of high quality will have a high price; those who are of poor quality will have a low price. If the material of 2 + - 3 - Jiang - 4 - (Sanjiang methyl) is excellent and the production is skillful, the price will be very high. Second, it depends on supply and demand. If the supply exceeds the demand, the price will fall; if the supply exceeds the demand, the price will rise. If there are many people in the market who need this 2 + - 3 - Jiang - 4 - (Sanjiang Methyl), and the goods are scarce, the price will rise; if the stock of goods is like a mountain, and there are few people who want to buy, the price will go down. Third, changes in the situation also have an impact. The chaos of the world, the abundance of the year, are all related to prices. In a peaceful world, all industries are prosperous, and prices may be stable or rising; in troubled times, business is blocked, and prices may be volatile. And if the year is prosperous, all goods are abundant, and prices may drop slightly; in case of famine, materials are scarce, prices will rise.
    There are many details about this product, such as the quality of the texture, the supply and demand of the city, and the state of the situation, so it is difficult to determine its price. It is necessary to carefully observe its quality, understand the supply and demand, and understand the situation in order to accurately measure the price of its market.
    What are the precautions for storing and transporting 2-chloro-3-fluoro-4- (trifluoromethyl) pyridine?
    2 + -

    Its chemical properties are special, and when storing, the first environment should be selected. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammable, explosive and other characteristics, if the ambient temperature is too high or the ventilation is not smooth, it is easy to cause accidents and endanger the safety of the surrounding area.
    In addition, the material of the storage container is also crucial. A suitable container must be selected to prevent it from chemically reacting with the container, causing damage to the container and causing material leakage. For example, if the substance is corrosive, it needs to be contained in containers made of anti-corrosive materials.
    As for transportation, the transportation vehicle must take protective measures. Equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, the driver must drive slowly and avoid severe operations such as sudden braking and sharp turning to prevent damage to the container due to turbulence.
    Transportation route planning should not be ignored. Sensitive areas such as densely populated areas and water source protection areas should be avoided to reduce the harm caused by accidents during transportation.
    And transportation personnel must undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. In the event of an emergency such as a leak, prompt and accurate response measures can be taken to minimize losses and hazards.
    What are the physical and chemical properties of 2-chloro-3-fluoro-4- (trifluoromethyl) pyridine
    2 + -Deuterium-3 + -tritium-4- (tritium methyl) is a very special substance. Its physical properties are unique, because it contains deuterium, tritium and other heavy hydrogen isotopes, the mass is larger than that of ordinary hydrogen-containing substances. At room temperature and pressure, its state may be different from that of ordinary hydrogen-containing analogs, and the melting boiling point may be higher due to the force between heavier atoms.
    Furthermore, its density will also be higher than that of the corresponding ordinary hydrogen compound, due to the increase in atomic mass. In terms of solubility, due to its structure being different from that of ordinary hydrogen-containing compounds, the solubility characteristics in various solvents may be different, and the solubility in some organic solvents may be different from that of ordinary analogs.
    As for their chemical properties, the presence of deuterium and tritium makes the bond energies of C-D and C-T slightly different from those of C-H. This difference causes the steps involved in the fracture and formation of these bonds in chemical reactions to be different from those containing ordinary hydrogen. For example, in some redox reactions and substitution reactions, the reactivity may be changed due to isotope effects.
    And because it contains tritium methyl groups, the reactivity on the methyl group is also affected by tritium. In nucleophilic substitution reactions, the density distribution of the electron cloud of the atoms or groups attached to the tritium methyl group changes, which in turn affects the difficulty of the reaction. And because tritium is radioactive, when this substance participates in a chemical reaction, it may have a potential impact on the reaction process due to radioactive decay, or change the microscopic environment of the reaction system, causing subtle changes in the reaction path.