Pyridine 2 6 Diethanol
pyridine pyrrole pyrazine piperidine piperazine

pyridine-2,6-diethanol

    Specifications

    HS Code

    139809

    Chemical Formula C9H13NO2
    Molecular Weight 167.205 g/mol
    Appearance Colorless to light yellow viscous liquid
    Odor Characteristic odor
    Solubility In Water Soluble
    Boiling Point Approx. 307 - 308 °C
    Density Approx. 1.12 g/cm³
    Flash Point Approx. 152 °C
    Ph Aqueous Solution Approx. 7 - 9
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

    As a leading pyridine-2,6-diethanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of pyridine-2,6-diethanol?
    Pyridine-2,6-diethyl alcohol is also an organic compound. It has many chemical properties.
    This substance is colorless to light yellow liquid with a specific odor. In terms of solubility, it is soluble in water and common organic solvents. Due to the fact that the hydroxyl groups in the molecule can form hydrogen bonds with water molecules, it is hydrophilic, and the organic groups give it affinity with organic solvents.
    On reactivity, the presence of the pyridine ring makes the compound basic. The nitrogen atom of the pyridine ring contains lone pairs of electrons, which can accept protons and react with acids to form salts. And the pyridine ring can undergo electrophilic substitution reaction. Under suitable conditions, halogenation, nitrification, sulfonation and other reactions can be carried out. However, due to the electron-withdrawing effect of nitrogen atoms, the reaction activity is slightly lower than that of the benzene ring, and the substitution check point is also affected by its positioning effect.
    Furthermore, the hydroxyl groups in the molecule are also active. Hydroxyl groups can undergo esterification reactions, and form corresponding ester compounds with carboxylic acids or acyl chlorides under the action of catalysts. Hydroxyl groups can also participate in dehydration reactions, under appropriate conditions, intermolecular dehydration to ether, or intramolecular dehydration to form compounds containing double bonds.
    In addition, pyridine-2,6-diethyl alcohol is widely used in the field of organic synthesis. It is often used as an intermediate to prepare fine chemicals such as medicines, pesticides, and dyes. It also plays an important role in materials science and other fields.
    What are the main uses of pyridine-2,6-diethanol?
    Pyridine-2,6-diethanol has a wide range of uses. In the chemical industry, it is often used as a raw material for organic synthesis. It can participate in many chemical reactions and help generate various important organic compounds. For example, in the pharmaceutical field, through specific reaction paths, it can become a key intermediate for the synthesis of certain drugs, which is of great significance for drug development and production.
    In the field of materials science, pyridine-2,6-diethanol also has a place. It can be used as a modifier to integrate into polymer materials to optimize the properties of materials. For example, to enhance the stability and flexibility of materials, or to change their solubility, thereby broadening the application scenarios of materials and playing an important role in the preparation of plastics, fibers and other materials.
    Furthermore, in the field of catalysis, pyridine-2,6-diethanol can act as a ligand and combine with metal ions to form complexes with specific catalytic activities. Such complexes can catalyze a variety of chemical reactions, improve reaction efficiency and selectivity, and show unique value in industrial catalysis processes, contributing greatly to the efficient and green process of chemical production.
    In summary, pyridine-2,6-diethanol has important uses in chemical, pharmaceutical, materials and catalysis fields due to its unique chemical properties, providing assistance for the development of various fields.
    What is the synthesis method of pyridine-2,6-diethanol?
    To prepare pyridine-2,6-diethyl alcohol, you can follow the following method.
    First take pyridine as the starting material, pyridine is basic and aromatic. React with appropriate halogenated ethanol under suitable reaction conditions. This reaction should be carried out in an organic solvent, such as dimethylformamide (DMF) or dichloromethane, etc. Such solvents can dissolve the reactants well and promote the smooth reaction.
    The reaction requires the participation of bases, such as potassium carbonate, sodium carbonate, etc. The role of bases is to neutralize the hydrogen halides generated by the reaction, so that the equilibrium shifts in the direction of the product. The reaction temperature also needs to be precisely controlled, usually under moderate heating conditions, between about 50 and 80 degrees Celsius. If the temperature is too low, the reaction rate is slow; if the temperature is too high, it may cause side reactions.
    Another way is to activate the pyridine first. For example, by introducing some activating groups on the pyridine ring, the pyridine ring can be more easily reacted with ethanol derivatives. After activation, it can be reacted with ethanol-related reagents to improve the selectivity and yield of the reaction.
    After the reaction is completed, the product needs to be separated and purified. First, the conventional extraction method uses a suitable organic solvent to extract with the aqueous phase to enrich the product in the organic phase. After that, the organic solvent is removed by vacuum distillation, and the corresponding fraction is collected according to the boiling point characteristics of the product. The high purity pyridine-2,6-diethyl alcohol can also be obtained by column chromatography. In this way, the synthesis of pyridine-2,6-diethyl alcohol can be achieved according to the above steps and methods.
    What are the precautions for pyridine-2,6-diethanol in storage and transportation?
    For pyridine-2,6-diethanol, many things need to be paid attention to during storage and transportation.
    Its nature is more active, and it is prone to danger in case of heat or open flame. Therefore, when storing, look for a cool, dry and well-ventilated place, away from fire and heat sources. The temperature of the warehouse should be controlled within a suitable range to prevent its volatilization from being exacerbated or other accidents caused by excessive temperature.
    Furthermore, pyridine-2,6-diethanol is corrosive to a certain extent, and there are strict requirements for the material of the container in contact with it. Corrosion-resistant materials, such as special plastic containers or specific metal materials, should be selected to prevent the container from being corroded and leaking. The storage place should be equipped with corresponding emergency treatment equipment and suitable containment materials. If there is any leakage, it can be dealt with in time.
    During transportation, do not slack off. Containers should be ensured to be stable to prevent leakage due to collision and dumping. Transportation vehicles need to be equipped with fire extinguishing equipment and leakage emergency treatment equipment. Transport personnel should be familiar with the characteristics and emergency treatment methods of pyridine-2,6-diethanol, and the transportation route should avoid crowded areas and important facilities.
    In addition, pyridine-2,6-diethanol may be harmful to the environment, and it must not be leaked to the environment during storage and transportation. If it is accidentally leaked, it should be dealt with promptly in accordance with relevant procedures to reduce the harm to the environment.
    What are the effects of pyridine-2,6-diethanol on the environment and the human body?
    The impact of pyridine-2,6-diethyl alcohol on the environment and the human body has not been clearly stated in ancient times, but it is now reasonable.
    In terms of the environment, if it is scattered in nature, it may cause ecological disturbance. The reason is unknown. It may change in water and soil, vegetation, insects, fish, birds and beasts, etc. Or because of its chemical characteristics, it may phase with surrounding substances, causing water quality to change, soil variation, plant growth or resistance, insects, fish, birds and beasts to breathe or chaos. And its degradation path is unknown, or it accumulates in the environment and becomes a hidden danger.
    As for the human body, there are also various worries. Its ability to enter the body through the mouth, nose, skin, or disturb the viscera. Those who have internal organs, the cardinal of the human body, if they are invaded by it, fear that the qi and blood will not be smooth, and the meridians will be blocked. In light cases, there may be skin itching, mouth and nose discomfort; in severe cases, it may damage the ability of the liver and kidneys, resulting in loss of qi and blood, and confusion. And long-term exposure to it, or increased risk of disease, such as cancer, etc., is also unknown.
    Although the scientific research on pyridine-2,6-diethyl alcohol is not complete, its potential harm to the environment and the human body cannot be ignored. Be careful and wait for it, study its nature, explore its danger, and prevent it from developing, so as to protect the environment and the safety of the human body.