Pyridine 2 5 Dichloro 3 Methyl
pyridine pyrrole pyrazine piperidine piperazine

Pyridine, 2,5-dichloro-3-methyl-

    Specifications

    HS Code

    562948

    Chemical Formula C6H5Cl2N
    Molar Mass 162.017 g/mol
    Appearance Solid (predicted)
    Boiling Point Unknown
    Melting Point Unknown
    Density Unknown
    Solubility In Water Low (predicted)
    Vapor Pressure Low (predicted)
    Flash Point Unknown
    Pka Unknown
    Logp Around 3 (estimated)

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    General Information
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    Frequently Asked Questions

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    What are the physical properties of 2,5-dichloro-3-methylpyridine?
    The physical properties of 2% 2C5-dihydro-3-methylfuran are as follows:
    This substance is mostly colorless to light yellow liquid at room temperature, and it is clear and transparent, as pure as jade dew. Its smell is unique, with a faint fragrance, but it is not rich and pungent, just like a faint fragrance of flowers in the spring breeze, quietly drilling into the nose.
    When it comes to the boiling point, the melting point is quite low, about -80 ° C, like ice on a cold night, which is easy to melt; the boiling point is in the range of 80-82 ° C, just like warm water in summer, which turns into dense water vapor after a little heat. This characteristic makes it easy to change from liquid to gaseous state under normal heating conditions, rising and drifting like clouds. < Br >
    In terms of density, it is about 0.91g/cm ³, which is slightly lighter than water. If it is placed in the same place as water, it will float lightly on the water surface, just like a boat floating leisurely.
    In terms of solubility, it can be soluble in many organic solvents, such as ethanol, ether, etc., just like fish entering water and can perfectly blend with it; however, the solubility in water is very small, just like oil and water.
    Volatility is also strong. In an open environment, it will evaporate rapidly in a short time, such as dew in the early morning, which disappears quickly as the sun rises.
    In addition, its refractive index is about 1.430 to 1.435. When light passes through, it will be refracted at a specific angle, producing a wonderful optical effect, as if drawing a unique picture in the world of light. The above physical properties make it unique and valuable in many fields such as chemical industry and medicine.
    What are the chemical properties of 2,5-dichloro-3-methylpyridine?
    2% 2C5-difluoro-3-methylpyridine is an organic compound with special chemical properties. It is colorless to pale yellow liquid and has a wide range of uses in the field of organic synthesis.
    This compound contains fluorine atoms and methyl groups, and has strong electronegativity of fluorine atoms. It causes large polarity of C-F bonds, which affects molecular physical and chemical properties. Because of its high C-F bond energy and stable structure, 2% 2C5-difluoro-3-methylpyridine has good chemical stability and is difficult to react under some conditions. And the presence of fluorine atoms enhances the lipophilicity of molecules, which affects the solubility and reactivity of compounds in some organic reactions.
    Methyl as the power supply group can increase the electron cloud density of the pyridine ring and change its reaction check point and activity. This structural property makes 2% 2C5-difluoro-3-methylpyridine prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Because the pyridine ring is basic, it can form salts with acids, or be used as a base catalyst in some reactions.
    2% 2C5-difluoro-3-methylpyridine is important in the fields of pharmaceutical chemistry and pesticide chemistry. It can be used as a key intermediate to construct specific bioactive compounds through a series of reactions, such as the development of new antibacterial, antiviral drugs, or high-efficiency and low-toxicity pesticides.
    In addition, due to the presence of fluorine atoms and methyl groups, 2% 2C5-difluoro-3-methyl pyridine may have potential applications in the field of materials science, such as the preparation of polymer materials with special properties, or for the synthesis of organic optoelectronic materials. By virtue of its unique electronic structure and chemical stability, the material is endowed with specific optoelectronic properties.
    What are the main uses of 2,5-dichloro-3-methylpyridine?
    2% 2C5-difluoro-3-methylpyridinonitrile, this is an important organic compound. Its main use is of critical significance in many fields.
    In the field of medicinal chemistry, it is an important intermediate. With a specific chemical reaction path, it can be skillfully converted into various specific drug molecules. Such as the synthesis of some new antibacterial drugs, this compound plays an indispensable role. Due to its unique chemical structure, it endows the synthesized drugs with unique antibacterial activity, which can effectively inhibit the growth and reproduction of specific pathogens and escort human health.
    In the field of pesticide chemistry, it also plays a pivotal role. Using it as a starting material and through a series of carefully designed reactions, highly efficient and low-toxicity pesticide products can be prepared. Such pesticides demonstrate excellent killing ability against crop pests, while having minimal impact on the environment. For example, for some common pests such as aphids and borers, pesticides synthesized based on 2% 2C5-difluoro-3-methylpyridinonitrile can precisely combat pests, ensure the growth of crops, and help agricultural harvests.
    In the field of materials science, it also has a unique application. It can participate in the synthesis of polymer materials with special properties. For example, the synthesis of new plastics with excellent heat resistance and corrosion resistance. Such plastics are widely used in high-end fields such as aerospace, electronics and electrical appliances, and can meet the strict performance requirements of materials in these fields.
    2% 2C5-difluoro-3-methylpyridinonitrile, with its unique chemical structure, plays a key role in many fields such as medicine, pesticides, materials science, etc., and contributes greatly to the development of various fields.
    What are the synthesis methods of 2,5-dichloro-3-methylpyridine?
    There are many methods for the synthesis of 2% 2C5-difluoro-3-methylpyridine. The following are several common methods.
    First, the halogenated pyridine method. Halogenated pyridine is used as the starting material, and fluorine atoms are introduced through the nucleophilic substitution reaction of halogen atoms with fluorine-containing reagents; and then methyl is introduced through the methylation reaction. This process requires precise control of the reaction conditions, such as temperature, reaction time, and ratio of reactants. Different activities of halogen atoms make the reaction difficult and different, and the nucleophilic substitution reaction may be accompanied by side reactions, which affect the purity and yield of the target product.
    Second, the conversion method of pyridine derivatives. Select suitable pyridine derivatives and use their specific functional groups for conversion. For example, using pyridine derivatives containing hydroxyl groups and amino groups as raw materials, the target molecular structure is gradually constructed through a series of reactions such as substitution, elimination, and addition. This path requires a thorough understanding of the reaction mechanism of each step in order to effectively optimize the reaction conditions and improve the yield of the product.
    Third, transition metal catalysis method. With the help of transition metal catalysts, such as palladium and nickel, fluorine-containing reagents can be catalyzed to react with pyridine derivatives. Transition metals can activate the reactants, reduce the activation energy of the reaction, and make the reaction more likely to occur. This method has the advantages of mild reaction conditions and high selectivity, but the cost of the catalyst is high, and the separation and recovery are more complicated, which limits its large-scale application to a certain extent.
    Fourth, cyclization reaction method. The pyridine ring is constructed by multi-step reaction, and fluorine atoms and methyl groups are introduced during the cyclization process. This approach requires clever design of the reaction route to ensure the smooth progress of the cyclization reaction, while taking into account the accuracy of the introduction of fluorine atoms and methyl groups. Cyclization reaction conditions are usually harsh, and the requirements for reaction equipment and operation are quite high.
    All synthesis methods have advantages and disadvantages. In practical application, it is necessary to comprehensively consider the cost of raw materials, reaction conditions, product purity and yield, environmental protection requirements and many other factors, and carefully choose the optimal synthesis path.
    What are the precautions for storing and transporting 2,5-dichloro-3-methylpyridine?
    2% 2C5-difluoro-3-methylpyridine is a valuable chemical raw material. During storage and transportation, many matters need to be carefully paid attention.
    First storage environment. This substance should be stored in a cool, dry and well-ventilated place. If the ambient humidity is too high, it is easy to cause moisture and deterioration; if the temperature is too high, it may cause its chemical properties to be unstable and even trigger dangerous reactions. Be sure to keep away from fires and heat sources. Because of its flammability, there is a risk of combustion and explosion in case of open flames and hot topics. And it needs to be stored separately from oxidants, acids, bases, etc., to avoid mixed storage to prevent chemical reactions.
    Secondary and packaging requirements. The packaging must be tight to ensure that there is no leakage. The packaging materials used must have good corrosion resistance and sealing to prevent external factors from affecting the quality of the material. If it is packed in a suitable glass bottle or plastic bottle, it should be reinforced with a strong carton or wooden box, and the information such as the name, nature and danger warning of the substance should be clearly marked on the packaging.
    When transporting, there are also many key points. The transportation vehicle must have corresponding qualifications and safety facilities. The driver and escort must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. During transportation, severe vibration, impact and sun exposure should be prevented. If transporting in summer, special attention should be paid to taking cooling measures to avoid danger caused by excessive temperature in the car. And the transportation route should try to avoid densely populated areas and environmentally sensitive areas to prevent serious consequences from accidental leakage.
    In short, the storage and transportation of 2% 2C5-difluoro-3-methylpyridine is related to safety and quality, and all links cannot be slack. It must be operated in strict accordance with regulations to ensure foolproof.