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What is the chemical structure of N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine?
This is the structural analysis of organic compounds. "N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine", its structure can be gradually analyzed from the naming.
Pyridine is a six-membered nitrogen-containing heterocyclic ring, and this compound has a pyridine ring as the core structure. At the 2nd and 6th positions of the pyridine ring, each is connected with an amino group (-NH2O), which is the meaning of "pyridine-2,6-diamine".
At the 3rd position of the pyridine ring, a nitro group (-NO ²) is connected, that is, "3-nitro".
And "N6- [ (4-fluorophenyl) methyl]" means that on the nitrogen atom (N6) of the pyridine ring, there is a [ (4-fluorophenyl) methyl] structure connected. In this structure, "4-fluorophenyl" is a benzene ring with a fluorine atom (-F) at the 4th position, and "methyl" (-CH2-) is connected between the benzene ring and the nitrogen atom at the 6th position of the pyridine ring.
In summary, the structure of this compound is based on a pyridine ring, with an amino group at the 2,6 position, a nitro group at the 3 position, and a nitrogen atom at the 6 position with a [ (4-fluorophenyl) methyl] structure, thus constituting its unique chemical structure.
What are the main uses of N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine?
N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine, an organic compound. It has a wide range of uses in the field of medicinal chemistry and is often a key intermediate for the creation of new drugs. Due to its unique structure and specific biological activity, it can be modified to develop drugs for specific diseases, such as anti-tumor and antiviral drugs, etc., by precisely acting on the target of diseased cells, it can play a therapeutic role.
In the field of materials science, it may be involved in the preparation of functional materials. Due to its molecular structure endowing special photoelectric properties, it can be used to make organic Light Emitting Diodes (OLEDs), solar cells and other materials, adding unique electrical and optical properties to the materials and improving the performance of related devices.
Furthermore, it also has potential uses in pesticide chemistry. With reasonable design and modification, high-efficiency, low-toxicity and environmentally friendly pesticides may be developed. With the action mechanism against specific pests or pathogens, it can effectively prevent and control crop diseases and pests, ensure agricultural production, and improve the yield and quality of agricultural products.
This compound has important value in many scientific research and application fields, providing a key foundation for many research and innovation. With the progress of science and technology, its application prospects may be broader.
What is the synthesis method of N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine?
To prepare N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine, the following method can be followed.
First take the pyridine as the group and introduce the amino group at its 2,6 position. This step can be achieved by a series of reactions with pyridine with suitable reagents. For example, a specific halogenated pyridine reacts with ammonia or amino-containing reagents under appropriate temperature, pressure and catalyst conditions, so that the amino group successfully replaces the halogen atom to obtain pyridine-2,6-diamine.
Then, the nitro group is introduced at the 3rd position of the pyridine ring. In this step, a nitrifying reagent, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid, is usually used to control the reaction temperature and time, so that the nitro group can be selectively introduced into the 3-position. Due to the distribution characteristics of the electron cloud of the pyridine ring, the reaction conditions should be paid attention to to to prevent excessive nitrification or other side reactions.
Finally, connect the (4-fluorophenyl) methyl group at the N6 position. This step can be selected from (4-fluorobenzyl) halides, such as (4-fluorobenzyl) chloro or (4-fluorobenzyl) bromide, and react with the prepared 3-nitropyridine-2,6-diamine under basic conditions. The alkali can capture the amino hydrogen, and the generated negative ion nucleophilic attacks the carbon connected to the halogen atom of the (4-fluorobenzyl) halide, and the halogen ion leaves to achieve the synthesis of N6- [ (4-fluorophenyl) methyl] -3 -nitropyridine-2,6 -diamine.
After each step of the reaction, it needs to be separated and purified, such as extraction, crystallization, column chromatography, etc., to obtain a high-purity product, and the reaction conditions of each step need to be finely adjusted to make the overall synthesis efficient and smooth.
What are the physicochemical properties of N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine?
N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine, this is an organic compound. Its physical and chemical properties are crucial in various research fields, and the following are described in detail.
Looking at its properties, it is mostly solid at room temperature and pressure. This compound has unique chemical activity due to its molecular structure containing specific functional groups, such as amino groups and nitro groups. Amino groups are alkaline and can react with acids to form corresponding salts. The presence of nitro groups changes the electron cloud distribution of the compound, affecting its chemical stability and reactivity. < Br >
Discuss solubility, because its molecules have both polar and non-polar parts, and their solubility in organic solvents may be better than that of water. The non-polar structure of aromatic rings and fluorophenyl groups makes them quite soluble in organic solvents such as dichloromethane and chloroform. However, because amino groups and nitro groups can form hydrogen bonds with water molecules, they also have a certain solubility in water, but they are relatively limited.
Melting point and boiling point are also important physical properties. The melting point is affected by intermolecular forces. The molecules of this compound can interact with hydrogen bonds and van der Waals forces, so that their melting point is within a certain range. The boiling point is related to the energy required for molecules to break free from the liquid phase. Due to the intermolecular forces, the boiling point also has specific values, but the exact melting point and boiling point need to be accurately determined by experiments. < Br >
In terms of stability, nitro is an electron-withdrawing group, which may reduce the electron cloud density of the pyridine ring and enhance its chemical stability. However, under specific conditions, such as high temperature, strong acid, and strong alkali environment, the compound may react and cause structural changes.
In terms of spectral properties, due to the conjugated system and specific functional groups, there are corresponding characteristic absorption peaks in the infrared spectrum, which can help identify functional groups. In NMR spectroscopy, hydrogen and carbon atoms in different chemical environments exhibit unique chemical shifts, providing key information for structure analysis.
The physicochemical properties of N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine are determined by its molecular structure and are of great significance in the fields of organic synthesis and medicinal chemistry.
What is the price range for N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine in the market?
I have not obtained the confirmed price of N6- [ (4-fluorophenyl) methyl] -3-nitropyridine-2,6-diamine in the market. This compound is very common, and its price varies depending on factors such as quality, source, purchase quantity, and market conditions.
If the purchase quantity is small, it is purchased from a chemical reagent supplier, and its price may be high due to research and development purposes. The synthesis of this chemical may require multiple steps of reaction, and the raw materials and processes are complicated, resulting in high cost. A small amount of price may be tens to hundreds of yuan per gram.
If you buy it in large quantities, it is for industrial use, and you can directly negotiate with the manufacturer to reduce the cost by scale effect, and the price per gram may be reduced to a few to tens of yuan. However, such purchases often require qualifications and agreements.
To know the exact price, you can consult chemical reagent suppliers, chemical product trading platforms, or negotiate with manufacturers to obtain accurate quotations in the current market.