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What is the chemical structure of N '- [ (Z) - (3-methoxy-4-oxocyclohexyl-2,5-diene-1-subunit) methyl] pyridine-4-formylhydrazide?
This is a question about the chemical structure. To clarify the chemical structure of N '- [ (Z) - (3-methoxy-4-oxo-cyclohex- 2,5-diene-1-subunit) methyl] pyridine-4-formamide. In this structure, the pyridine ring is the key part, and the pyridine-4-formamide, which means that the 4th position of the pyridine ring is connected with a formamide group. And the N 'linked part, [ (Z) - (3-methoxy-4-oxo-cyclohexyl-2,5-diene-1-subunit) methyl], contains a cyclohexene structure, and has a methoxy group at position 3, an oxygen group at position 4, and a methylene group at position 1, which is then connected to the nitrogen atom of the pyridine ring. Its structure is complex and delicate, and the spatial position and interaction of each group have a key influence on the chemical properties and reactivity. In this way, the chemical structure of this compound is known.
What are the physical properties of N '- [ (Z) - (3-methoxy-4-oxocyclohexyl-2,5-diene-1-subunit) methyl] pyridine-4-formylhydrazide?
N '- [ (Z) - (3-methoxy-4-oxo-cyclohexyl-2,5-diene-1-subunit) methyl] p-4-methylbenzenesulfonamide has the following physical properties:
This substance often appears in a specific form at room temperature and pressure. Generally speaking, it may be a crystalline solid with a certain color, or a white to yellowish crystal, which is determined by its molecular structure and aggregation state.
In terms of solubility, its dissolution in organic solvents is worthy of attention according to the principle of similar miscibility. It may have a certain solubility in polar organic solvents such as ethanol and acetone, because its molecular structure contains both polar groups, which help to form interactions with polar solvent molecules and promote dissolution; however, the solubility in water is relatively low, which is mainly due to the fact that the hydrophobic part of the whole molecule occupies a certain proportion, resulting in a weak force with water molecules.
Regarding the melting point, the substance has a specific melting point range. This melting point is determined by the interaction of its intermolecular forces, including van der Waals force, hydrogen bonds, etc. Through precise experimental determination, its relatively accurate melting point value can be determined. The melting point is of great significance for the purity identification of the substance and in some reactions or treatment processes involving temperature changes. < Br >
Its density is also an important physical property. The density reflects the mass per unit volume of a substance and is related to the degree of close packing of molecules. It provides key data for the conversion of mass and volume in practical applications.
From the perspective of volatility, due to the characteristics of intermolecular forces, it has low volatility at room temperature, which makes it relatively stable during storage and use, and is not prone to losses due to volatilization or other problems.
What are the main uses of N '- [ (Z) - (3-methoxy-4-oxocyclohexyl-2,5-diene-1-subunit) methyl] pyridine-4-formylhydrazide?
This is a chemical-related content that has been coded. After analysis, it means "What is the main use of N '- [ (Z) - (3-methoxy-4-oxo cyclohexyl-2,5-diene-1-subunit) methyl] for its-4-methylbenzonitrile?".
"Tiangong Kaiwu" is an ancient scientific and technological masterpiece in our country. Although this compound is not directly described, the book discusses the characteristics and uses of various substances in the fields of chemical industry, metallurgy, machinery, etc., providing ideas for us to understand the use of substances from a traditional perspective.
From the perspective of traditional chemistry, it is speculated that such compounds containing methoxy, methylene, nitrile and other groups may have certain biological activities. Methoxy can enhance the lipid solubility of compounds, which is conducive to their penetration of biofilms, or can be used in drug research and development. As a lead compound, it is optimized by structural modification and used in disease treatment.
Furthermore, the compound has a conjugated system or has optical properties, which can be used in the field of optical materials, such as the production of special optical filters, photochromic materials, etc., which change color due to structural changes under light for optical information storage and display.
At the same time, nitrile groups have high reactivity and can be converted into other functional groups through hydrolysis, addition and other reactions. They are used in organic synthesis intermediates to prepare more complex organic compounds and provide raw materials for Chemical Product Research & Development.
What are the synthesis methods of N '- [ (Z) - (3-methoxy-4-oxocyclohexyl-2,5-diene-1-subunit) methyl] pyridine-4-formylhydrazide?
In order to obtain the synthesis method of\ (N '- [ (Z) - (3-methyl-4-oxo-cyclohexane-2,5-diene-1-subunit) methyl] p-4-methylbenzonitrile, the following methods can be followed:
First, the phenylacetonitrile derivative with the corresponding substituent is used as the starting material. First, the derivative undergoes nucleophilic substitution reaction with the appropriate halogenated hydrocarbon under alkaline conditions. The basic reagent can be selected from potassium carbonate, sodium hydride, etc., and the reaction solvent can be selected from tetrahydrofuran, N, N-dimethylformamide and the like. In this way, the desired substituent can be introduced at the methyl position of phenylacetonitrile. Subsequently, by means of a specific cyclization reaction, such as under the catalysis of Lewis acid, the cyclization occurs in the molecule to construct the ring structure in the target product. After the reaction is completed, the pure target product can be obtained by separation, purification and other operations, such as column chromatography and recrystallization.
Second, phenolic compounds are used as starting materials. First, the phenolic hydroxyl group is properly protected to prevent its interference in subsequent reactions. Then, through a series of electrophilic substitution reactions, specific substituents such as methyl groups and nitrile groups are introduced into the phenolic ring. This process can be achieved by means of Friedel-Crafts reaction. After that, the phenolic hydroxyl group is restored through the deprotection step, and then the phenolic hydroxyl group is converted into a leaving group with a suitable reagent, and then reacts with another nucleophile containing the corresponding substituent to construct the structural framework of the target product. Finally, the target product is purified.
Third, the cyclohexene derivative is used as the starting material. The cyclohexene is first oxidized to construct the cyclohexenone structure. In this step, a suitable oxidizing agent, such as Jones reagent, can be selected. Subsequently, through carbon-carbon bond formation reactions, such as Wittig reaction, Horner-Wadsworth-Emmons reaction, etc., the substituent containing the benzonitrile structure is introduced at a specific position of the cyclohexenone. Finally, the necessary reduction, isomerization and other reactions are carried out on the reaction product, so that the molecular structure finally meets the requirements of the target product, and then the pure\ (N '- [ (Z) - (3-methyl-4-oxo cyclohexyl-2,5-diene-1-subunit) methyl] p-4-methylbenzonitrile\) is obtained through separation and purification.
What should be paid attention to when storing and using N '- [ (Z) - (3-methoxy-4-oxocyclohexyl-2,5-diene-1-subunit) methyl] pyridine-4-formylhydrazide?
This is related to the precautions for the storage and use of N '- [ (Z) - (3-methoxy-4-oxy-cycloethyl-2,5-dialdehyde-1-subunit) methyl] for its-4-methanesulfonamide. These chemicals are very toxic and can endanger life and health if they are not careful.
When storing, the first environment. It should be placed in a cool, dry and well-ventilated place, away from fires and heat sources. Because of its flammability, high temperatures or open flames can easily cause combustion and cause accidents. It needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed to prevent violent chemical reactions.
When taking it, the protection must be thorough. Wear protective clothing, which can block chemicals from coming into contact with the body and protect the skin from corrosion and burns. Wear protective gloves to keep hands safe; wear goggles or face masks to protect your eyes from chemical splashes. During operation, keep air circulation, and you can use ventilation equipment to expel volatile harmful gases in time.
After the operation is completed, properly clean up the residue. Do not dump at will, and should be handed over to a professional treatment agency in accordance with relevant regulations. If you accidentally come into contact during operation, rinse with plenty of water as soon as possible. In severe cases, seek medical attention immediately.
These chemicals are related to safety, and must not be slack in storage and use. They must be operated in strict accordance with regulations to ensure safety.