N Methyl 4 4 Methylamino Phenoxy Pyridine 2 Carboxamide
pyridine pyrrole pyrazine piperidine piperazine

n-methyl-4-[4-(methylamino)phenoxy]pyridine-2-carboxamide

    Specifications

    HS Code

    191243

    Chemical Formula C15H17N3O3
    Molecular Weight 287.314 g/mol
    Appearance Solid (predicted)
    Boiling Point 523.6±50.0 °C at 760 mmHg (predicted)
    Melting Point 183 - 185 °C
    Logp 1.53 (predicted)
    Pka 13.73±0.70 (predicted)
    Solubility Soluble in DMSO, Methanol (Slightly)
    Density 1.262±0.06 g/cm³ (predicted)
    Vapor Pressure 0.0±1.4 mmHg at 25 °C (predicted)

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of n-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide
    This is the name of the organic compound, and its chemical structure is deduced according to this name. When resolved as follows.
    "N-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide", where "N-methyl" has a methyl group attached to the epiazine atom. "pyridine-2-carboxamide" shows the basic structure of pyridine-2-formamide, that is, the 2-carbon of the pyridine ring is connected with a formamide group.
    "4- [4- (methylamino) phenoxy]" indicates that the 4-position of the pyridine ring is connected with a substituent, which is [4- (methylamino) phenoxy], that is, phenoxy, and the 4-position of the phenyl ring is connected with methylamino.
    In summary, the chemical structure of the compound is pyridine-2-formamide as the parent nucleus. The 4-position of the pyridine ring is connected with a phenoxy group containing methylamino, and the nitrogen atom is also connected with a methyl group. Its structure is as follows: a pyridine ring, with a formamide group at the 2nd position, a phenoxy group at the 4th position, a methylamino group at the 4th position of the phenoxy group, and a methyl group on the nitrogen atom connected to the formamide group. In this way, according to the rules of organic chemical structure analysis, the chemical structure of this compound is obtained.
    What are the main uses of n-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide
    N-methyl-4- [4- (methylamino) phenoxy] pyridine-2-formamide, an organic compound, has important uses in many fields.
    In the field of pharmaceutical research and development, it may be a key intermediate. Because it has a specific chemical structure and activity, it can be converted into a drug molecule with specific pharmacological activity through a series of reactions by means of organic synthesis. For example, in the research of anti-tumor drugs, it can be used to build a core structural unit. By modification and optimization, innovative drugs with targeted effects on tumor cells can be obtained, which can inhibit their proliferation or induce apoptosis. < Br >
    In the field of materials science, it may participate in the creation of functional materials. For example, it can be used as a building block to prepare materials with special optoelectronic properties through molecular self-assembly or polymerization. Or it can be applied to the field of organic Light Emitting Diode (OLED) to endow materials with unique luminescent properties and improve the luminous efficiency and stability of devices; or it can play a role in sensor materials to achieve highly sensitive detection of targets through its selective interaction with specific substances.
    In agricultural chemistry, it may have potential agricultural value. Or it can be developed into a new type of pesticide after rational design and modification. For example, for specific pests or pathogens, it shows high inhibitory or killing activity, and compared with traditional pesticides, it has lower environmental toxicity and better biocompatibility, which contributes to the sustainable development of agriculture.
    In summary, N-methyl-4- [4- (methylamino) phenoxy] pyridine-2-formamide is widely used in the fields of medicine, materials and agricultural chemistry, providing a key material basis for technological innovation and development in various fields.
    What is the synthesis method of n-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide
    To prepare N-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide, it can be synthesized according to the following ancient method.
    First take pyridine-2-carboxylic acid, place it in a round-bottom flask with sulfuryl chloride, and apply moderate heating to make the two react. Pyridine-2-carboxylic acid is converted into pyridine-2-formyl chloride. The key to this step is the control of temperature and reaction time, so that the reaction is complete and pure pyridine-2-formyl chloride is generated.
    Then, the obtained pyridine-2-formyl chloride is slowly dropped into a reaction vessel containing N-methyl-4- (methylamino) phenol. An appropriate amount of acid binding agent, such as triethylamine, is added to this vessel in advance to neutralize the acid generated during the reaction and promote the positive progress of the reaction. This reaction is slowly stirred under a low temperature environment for a period of time to fully react the two to form an intermediate product.
    Furthermore, the intermediate product is separated and purified to remove impurities. Column chromatography or recrystallization can be used. Column chromatography requires careful selection of suitable silica gel fillers and preparation of suitable eluents to achieve effective separation; recrystallization requires careful selection of suitable solvents, control of cooling rate, and crystallization of the product to obtain a pure intermediate product.
    Finally, the pure intermediate product is placed under specific reaction conditions, and the necessary functional group transformation or modification is carried out to achieve the synthesis of the final target product N-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide. After this step is completed, the separation and purification steps are repeated to ensure the purity and quality of the product. < Br >
    During the synthesis process, each step requires fine operation, and the reaction process and conditions are closely monitored to ensure the smooth progress of each step of the reaction to obtain satisfactory yield and product purity.
    What is the safety of n-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide
    N - methyl - 4 - [4 - (methylamino) phenoxy] pyridine - 2 - carboxamide is an organic compound, and the safety of this substance needs to be carefully studied in combination with multiple factors.
    The first to bear the brunt is the toxicological properties. To understand its effects on organisms, a series of toxicological tests are often carried out in laboratory animals. Acute toxicity tests can help detect immediate reactions to the substance after short-term exposure, such as abnormal animal behavior, organ damage, or even death at high doses. Subacute and chronic toxicity tests focus on the effects of long-term low-dose exposure, or involve stunted growth and development, decline of specific organ function, etc. Mutagenicity testing is also key to explore whether the substance may induce genetic mutations or chromosomal aberrations. If there is such a risk, or the risk of genetic diseases and cancers in hyperplasia.
    Repeat, its environmental safety should not be underestimated. If the substance is released into the environment, its fate in different environmental media (water, soil, atmosphere) needs to be tested. In the aquatic environment, it may affect the survival, reproduction and behavior of aquatic organisms, causing damage to biodiversity. In the soil, it may change the structure and function of soil microbial community, affecting the normal operation of soil ecosystems. If it is volatile in the atmosphere, or participates in atmospheric chemical reactions, it will affect air quality.
    Furthermore, in terms of operational safety, there is also a risk of direct contact or inhalation of the substance during production and use. If there is a lack of appropriate protection, skin contact may cause irritation or allergic reactions; inhalation of its dust or vapor, or damage to the respiratory system. Therefore, the workplace must be equipped with good ventilation facilities and personal protective equipment to reduce the risk of personnel exposure.
    However, based on its chemical name alone, it is difficult to make accurate conclusions about safety. It is still necessary to rely on professional experimental data and detailed threat and risk assessment. In practical application, when strictly following safety operating procedures and relevant regulations and standards, to ensure the safety of personnel and the environment.
    What is the market prospect of n-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide?
    The market prospect of Guanfu n - methyl - 4 - [4 - (methylamino) phenoxy] pyridine - 2 - carboxamide remains to be seen. As far as the current situation is concerned, the field of medicine may be an important place for it. In the process of drug development, this compound may exhibit extraordinary biological activity due to its unique molecular structure, which is of great potential value for the treatment of many diseases.
    In terms of market demand, the demand for the prevention and treatment of various diseases is increasing, and the research and development of new drugs is imminent. If n - methyl - 4 - [4 - (methylamino) phenoxy] pyridine - 2 - carboxamide can emerge in pharmacological experiments, and its efficacy and safety are confirmed, it will be able to win a place in the pharmaceutical market.
    However, the challenges it faces cannot be ignored. The complexity of the synthesis process may lead to high production costs, which in turn affects its market competitiveness. And the road to new drug development is full of thorns, and it must go through rigorous clinical trials before it can be approved for marketing. Only by breaking through many difficulties can it be expected to shine.
    Furthermore, with the rapid progress of science and technology, similar competing products are also emerging one after another. If you want to stand out, in addition to ensuring your own excellent quality, you also need to make efforts in marketing, product promotion, etc., to be widely known and recognized.
    Overall, n-methyl-4- [4- (methylamino) phenoxy] pyridine-2-carboxamide Although the prospect is promising, the road ahead is long, and opportunities and challenges coexist. It will take time and careful management to know its final achievement in the market.