N'-HYDROXYPYRIDINE-4-CARBOXIMIDAMIDE

The chemical structure of "N '-hydroxypyridine-4-formamidine" is a key research object in the field of organic chemistry. This compound takes the pyridine ring as its core structure. The pyridine ring is a nitrogen-containing six-membered heterocyclic ring, which is aromatic and is often a key structural unit in many organic compounds.
At the 4th position of the pyridine ring, a formamidine group is connected. The structure of the formamidine group is formed by the connection of one carbon atom with two amino groups and one imino group. This structure endows the compound with specific chemical activity and reaction characteristics. The solitary pair of electrons on the nitrogen atom in the formamidine group makes it an electron donor to participate in many chemical reactions, such as nucleophilic substitution reactions.
And on the nitrogen atom (N '), there is also a hydroxyl group. The presence of hydroxyl groups greatly affects the physical and chemical properties of the compound. Hydroxyl groups have strong hydrophilicity, so the compound has good solubility in polar solvents. At the same time, hydroxyl groups can participate in the formation of hydrogen bonds, whether intramolecular hydrogen bonds or intermolecular hydrogen bonds. This hydrogen bonding has a significant impact on the stability, melting point, boiling point and other physical properties of the compound, as well as its aggregation state and reactivity in solution.
Overall, the chemical structure of "N '-hydroxypyridine-4-formamidine" shows unique chemical properties and potential application value through the combination of pyridine ring, formamidine group and hydroxyl group, and may have important uses in many fields such as medicinal chemistry and materials science.

N '-hydroxypyridine-4-formamidine, this substance has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of various drugs. In the creation of many antibacterial drugs, N' -hydroxypyridine-4-formamidine is often relied on as the starting material. After delicate chemical transformation, the molecular structure with specific antibacterial activities is shaped to resist the invasion of various pathogens and protect health.
In the field of pesticides, N '-hydroxypyridine-4-formamidine also plays an important role. It can be turned into a pesticide active ingredient through specific processes, or has insecticidal effects, accurately identifying and annihilating pests that harm crops; or has bactericidal properties, inhibiting the growth of pathogenic bacteria, ensuring the thriving growth of crops, and helping farmers harvest.
Furthermore, in the field of materials science, N '-hydroxypyridine-4-formamidine also has its uses. In the preparation of some functional materials, N' -hydroxypyridine-4-formamidine can be used as a unique chemical reagent to regulate the microstructure and properties of materials, so that the materials exhibit better stability, special optical or electrical properties, etc., to meet various technical needs and promote the progress of materials science.

The method of preparing "N '-hydroxypyridine-4-formamidine" is not detailed in ancient books, but it can be prepared according to the principles of modern chemistry in the following ways.
First, pyridine-4-formonitrile is used as the starting material. First, pyridine-4-formonitrile is placed in a suitable reaction vessel and dissolved in an appropriate amount of solvent. If a polar organic solvent is used, such as dimethyl sulfoxide (DMSO) or N, N-dimethylformamide (DMF), such solvents can effectively promote the reaction. Subsequently, appropriate hydroxylating reagents, such as hydroxylamine salts, are added, commonly such as hydroxylamine hydrochloride. In this process, an appropriate amount of alkali, such as potassium carbonate or sodium carbonate, needs to be added to adjust the pH of the reaction system and promote the reaction to move in the direction of generating the target product. The reaction temperature should be controlled within an appropriate range, usually under the condition of heating and reflux, and the reaction should continue for several hours. After the reaction is completed, N '-hydroxypyridine-4-formamidine can be obtained through the separation and purification steps of cooling, extraction, washing, drying, column chromatography, etc.
Second, pyridine-4-carboxylic acid is used as the starting material. First, the pyridine-4-carboxylic acid is converted into its acid chloride form. Chlorinated reagents such as dichlorosulfoxide or oxalyl chloride can be selected. React in an appropriate solvent, such as in anhydrous dichloromethane, at room temperature or under heating conditions, to convert the carboxylic acid into acid chloride. After that, the acid chloride reacts with hydroxylamine, and the reaction conditions, such as reaction temperature, pH, etc. After the reaction is completed, similar separation and purification operations are performed to remove impurities, and the target product can also be obtained.
Although these two methods can prepare N '-hydroxypyridine-4-formamidine, each has its own advantages and disadvantages. The former raw material pyridine-4-formonitrile is relatively easy to obtain, and the reaction step is slightly simpler; the latter uses pyridine-4-carboxylic acid as the starting material, although there is one more step to convert to acyl chloride, but the raw material source is wide, and the cost may be advantageous. In actual preparation, the choice needs to be weighed according to many factors such as the availability of raw materials, cost, and product purity requirements.

N '-hydroxypyridine-4-formamidine is a unique compound with unique physical properties. Looking at its properties, under room temperature and pressure, it is mostly in the state of white to quasi-white crystalline powder, which makes it preliminarily recognizable in many substances.
When it comes to solubility, the substance exhibits unique properties in water and common organic solvents. In water, it has a certain solubility. Due to the hydroxyl group and formamidine group contained in the molecular structure, it can interact with water molecules through hydrogen bonds, but the solubility is not very high, and the hydrophobicity of the Geinpyridine ring restricts it. In organic solvents, such as methanol, ethanol and other polar organic solvents, its solubility is more considerable than that of water, due to the strong interaction between polar solvents and the polar groups of the compound; while in non-polar organic solvents, such as n-hexane and benzene, the solubility is extremely low, because the polar characteristics of the molecule are difficult to compatible with non-polar solvents.
Melting point is also one of its important physical properties. After precise determination, its melting point is in a specific temperature range. This melting point value can provide a key basis for the identification of the compound, and it is also of great significance for the study of its physical state changes under different temperature environments. The determination of the melting point is closely related to the intermolecular forces. The hydrogen bonds and van der Waals forces between the molecules of the compound interact to jointly maintain the solid structure. When the temperature rises to the melting point, these forces are weakened, and the molecules can break free from the lattice binding, and the substance changes from solid to liquid.
In addition, the density of N '-hydroxypyridine-4-formamidine is also an important parameter. The density value reflects the quality of the substance in a unit volume. In practical application scenarios such as chemical production and preparation, the density parameter is indispensable for material measurement, mixing ratio control, etc., which is related to the accuracy of the production process and the stability of product quality.
In conclusion, the physical properties of N '-hydroxypyridine-4-formamidine, from appearance, solubility, melting point to density, lay the foundation for in-depth understanding and rational application of this compound.

I have not heard of the exact price of "N '-HYDROXYPYRIDINE - 4 - CARBOXIMIDAMIDE" in the market. However, the price of this product often changes due to many reasons. First, its production is difficult and easy. If the production process is complicated and the materials used are rare, the price will be high; otherwise, the price will be low. Second, the situation of demand and supply is also serious. If there is more supply and less supply, the price will rise; if the supply exceeds the demand, the price will drop. Third, the purity and impurity of the product also involve the price. Those who are pure are high in price; those who are pure are low in price.
If you want to know the exact price today, you should consult chemical material suppliers, pharmaceutical merchants, or find it on chemical trading platforms and pharmaceutical equipment transactions. Or you can search the Internet and observe the quotations of various merchants. However, the price changes frequently, and it is appropriate to check it in real time. Or you can consult with people in the industry or those who specialize in this way, and you can also get an approximate price. It is a pity that I have not obtained the exact price. If you are in a hurry to know the above things, you can get the price range.