N Ethyl 4 2 4 Fluoro 2 6 Dimethylphenoxy 5 1 Hydroxy 1 Methylethyl Phenyl 6 7 Dihydro 6 Methyl 7 Oxo 1h Pyrrolo 2 3 C Pyridine 2 Carboxamide
pyridine pyrrole pyrazine piperidine piperazine

N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

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    671661

    Chemical Name N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

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    As a leading N-Ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of N-Ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5- (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo [2,3-c] pyridine-2-carboxamide
    This is the name of an organic compound. Following its name, its chemical structure can be deduced as follows:
    The main structure of this compound is pyrrolido-pyridine containing nitrogen heterocycles. Its pyridine ring is hydrogenated by double bonds between positions 6 and 7, and there is a carbonyl oxygen at position 7, a hydrogen atom at position 1, a formamide group at position 2, and a nitrogen atom is connected to ethyl. This is the main substitution status of the pyridine ring.
    Formamyl group connected at position 2 of the pyridine ring has a specific substituent in the phenyl part. A fluorine-containing and dimethyl-containing phenoxy group is connected at position 4, and the phenyl ring on this phenoxy group has a fluorine atom at position 4 and a methyl group at position 2 and 6. 5-Position is connected to a tert-butyl alcohol group, that is, 1-hydroxy-1-methylethyl.
    In this way, the chemical structure of this complex organic compound is gradually outlined from the parts of the name. From the main ring of pyrrolido-pyridine to the substituents at each position, the complete chemical structure of this compound is obtained by sequential analysis.
    What are the physical properties of N-Ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5- (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo [2,3-c] pyridine-2-carboxamide
    N-ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5 - (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolido [2,3-c] pyridine-2-formamide, this is a rather complex organic compound. Looking at its structure, this compound is composed of a combination of many specific groups, each of which is endowed with its unique physical properties.
    Let's talk about its appearance first. It is usually white to off-white crystalline powder with fine texture, like the first snow in winter, pure and regular. Its melting point also has a specific range, about [X] ° C. This melting point value is like the unique logo of the compound, reflecting the strength of the interaction force between molecules. Below the melting point, it exists stably in a solid state and has a stable lattice structure. When the temperature approaches the melting point, the thermal motion of the molecules intensifies, and the lattice begins to loosen.
    In terms of solubility, the compound exhibits different behaviors in organic solvents. In common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), it has good solubility, just like fish get water, and the molecules can be evenly dispersed in it. However, the solubility in water is not good, which is mainly due to the large proportion of hydrophobic groups in its molecular structure, and it is difficult for water molecules to form effective interactions with it.
    In terms of stability, under normal environmental conditions, it is relatively stable, like a calm old man, and does not easily react with the surrounding environment. However, if it encounters a strong acid, strong alkali environment, or under extreme conditions such as high temperature and high humidity, its molecular structure may be damaged and chemical reactions occur, just like a building crumbling in a violent storm. For example, in a strong acid environment, some chemical bonds may break or rearrange; at high temperature, molecules may decompose. < Br >
    The density of this compound is also an important physical property. Although the exact value needs to be determined by precise experiments, according to its structure and similar compounds, its density should be within a reasonable range. This value is related to its sinking and mixing characteristics in different media.
    In addition, its refractive index also reflects the refractive ability of molecules to light, which is closely related to molecular structure. The specific refractive index can be used for compound purity and structure identification, like a unique optical fingerprint.
    What is the main use of N-Ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5- (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo [2,3-c] pyridine-2-carboxamide
    N-ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5 - (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolido [2,3-c] pyridine-2-formamide, which is a rather complex organic compound. Looking at its structure, we should know that these compounds have many wonderful uses in the field of medicinal chemistry.
    Because the structure and activity of organic compounds are closely related, the unique structure of this compound endows it with specific pharmacological activity. In the process of drug development, it is often necessary to carefully design the molecular structure to achieve the purpose of targeting specific biological targets.
    Or because of the ingenious arrangement of fluorine, methyl and other groups in its structure, it can accurately fit the activity check point of biological macromolecules or interfere with specific biochemical reaction pathways. Therefore, its main use may be to develop new drugs or to treat specific diseases. For some diseases caused by abnormal biological targets, this compound may be able to regulate the physiological mechanism of imbalance in organisms by virtue of its structural properties, so as to benefit patients.
    Or in basic experiments in medical research, as tool compounds to explore the functions and mechanisms of related biological targets, providing key clues and assistance for further understanding the mysteries of life processes and disease occurrence and development.
    What are the synthesis methods of N-Ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5- (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo [2,3-c] pyridine-2-carboxamide
    To prepare N-ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5 - (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolido [2,3-c] pyridine-2-formamide, there are many ways to synthesize it, and the common ones are as follows.
    First, specific fluorine-containing and pyridine-containing compounds are used as starting materials. The first step is to combine a fluorine-containing phenoxy compound with another phenyl compound containing a specific substituent in the presence of a suitable base and catalyst through a nucleophilic substitution reaction. This step requires fine regulation of the reaction temperature, time and the ratio of reactants to obtain the target intermediate. The base used may be potassium carbonate, sodium carbonate, etc.; the catalyst can be selected from copper salt or palladium salt, etc.
    Then, the resulting intermediate is fused with the pyridine derivative to construct the core structure of pyrrolido-pyridine through a condensation reaction. This condensation reaction may need to be carried out at high temperature and in a specific organic solvent to promote the smooth occurrence of the reaction. The organic solvents used, such as aromatic hydrocarbon solvents such as toluene and xylene, provide a suitable reaction environment.
    Then modify the core structure and introduce ethyl and formamido. The introduction of ethyl can be achieved by alkylation of halogenated ethane with pyridine nitrogen atoms; while the introduction of formamido requires a series of reaction steps such as acylation and aminolysis. The acylation reagent can be selected from suitable acid chloride or acid anhydride. During aminolysis, the amount of ammonia and reaction conditions need to be controlled to ensure the precise introduction of formamido.
    Second, pyridine-2-formic acid derivatives can also be used as the starting point. First modify the pyridine ring and introduce suitable substituents, such as methyl and fluorine atoms at specific positions in the pyridine ring. This process requires the use of specific halogenation, alkylation and other reactions, and precise control of the reaction check point. After
    , the key part of the molecule is gradually built by constructing substitutions such as phenoxy and hydroxyisopropyl on the phenyl ring. This step involves the etherification of phenolic hydroxyl groups to introduce phenoxy groups, and the reaction of suitable aldars, ketones and Grignard reagents to generate hydroxyisopropyl groups.
    Finally, the pyrrolidine structure is formed by intramolecular cyclization, and then ethyl and formamide groups are introduced to complete the synthesis of the target product. The cyclization reaction requires the selection of a suitable dehydrating agent or catalyst, and the introduction steps of ethyl and formamide groups also need to be carefully adjusted according to the specific reaction conditions to achieve the purpose of synthesis.
    Synthesis of this compound requires precise control of the conditions of each reaction step, from the purity of the raw materials, the ratio of the reactants, to the choice of reaction temperature, time, solvent and catalyst, all of which are crucial, so that the target product can be prepared efficiently and with high purity.
    N-Ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5- (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo [2,3-c] pyridine-2-carboxamide What are the potential side effects
    N-ethyl-4- [2- (4-fluoro-2,6-dimethylphenoxy) -5 - (1-hydroxy-1-methylethyl) phenyl] -6,7-dihydro-6-methyl-7-oxo-1H-pyrrolido [2,3-c] pyridine-2-formamide, which is a complex organic compound. Looking at its structure and properties, there may be some potential latent side effects.
    at the physiological and metabolic level, or interfere with specific cell signaling pathways. Some groups in its structure may interact with intracellular receptors, causing signal transduction disorders. For example, phenoxy and pyridine structures, or mimic natural signaling molecules in the body, mislead cellular responses and trigger abnormal physiological responses.
    Furthermore, it may have an impact on liver metabolism. Because of its complex structure, liver metabolic enzymes may face challenges when processing this substance. Or cause the accumulation of metabolic intermediates, damage the function of liver cells, and in the long run, or affect the normal detoxification and metabolism of the liver.
    In the nervous system, or interfere with nerve signaling due to binding to neurotransmitter receptors. Although there are no typical neuroactive groups in the structure, some subtle interactions may change the release, uptake or receptor sensitivity of neurotransmitters, which in turn affects the function of the nervous system, causing symptoms such as dizziness, fatigue, and cognitive impairment.
    In addition, in the immune system, it may have immunomodulatory effects. Its complex structure may be recognized by immune cells as foreign antigens, triggering an immune response. Or activate the immune system, trigger inflammation; or inhibit immune function, making the body vulnerable to pathogens.
    Of course, this is based on the speculation of the structural characteristics of the compound, and the actual side effects need to be confirmed by rigorous experiments and clinical studies.