N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide

This is a question related to the chemical structure of "N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide". To clarify its chemical structure, we should consider its name. This nomenclature follows the nomenclature of organic chemistry to guide us to understand its molecular composition.
"N- (cyanomethyl) ", showing that a cyano group (-CN) is attached to a methyl group (-CH2-), and this cyanomethyl group is attached to a nitrogen atom (N). "4- (trifluoromethyl) ", the 4th position of the epipyridine ring is connected with a trifluoromethyl group (-CF 🥰), which is a group with strong electronegativity. " "Pyridine-3-formamide", which means that the third position of the pyridine ring has a formamide group (-CONH 2).
In summary, the chemical structure of this compound is centered on the pyridine ring. The third position of the pyridine ring is connected to formamide group, the fourth position is connected to trifluoromethyl group, and the nitrogen atom is connected to cyanomethyl group. This structure endows the compound with unique chemical properties and may have important uses in organic synthesis, medicinal chemistry and other fields. The interaction of different groups in its structure affects the reactivity, solubility, biological activity and many other properties of the compound, laying the foundation for related research and applications.

N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide is an important compound in the field of organic chemistry. It has a wide range of uses and plays a key role in the field of medicinal chemistry. Due to its unique molecular structure, it can be used as a key intermediate in the process of drug development. With this intermediate, many bioactive compounds can be constructed, and then new drugs can be developed to fight various diseases, such as cancer, inflammation and other intractable diseases, or to exert their unique therapeutic effects.
In the field of materials science, this compound also shows extraordinary potential. It can be used to create high-performance functional materials, such as photoelectric materials, which can improve the optical and electrical properties of materials and contribute to the development of materials science.
Furthermore, it also has its uses in the field of agricultural chemistry. Or it can be used as a raw material for the synthesis of new pesticides, with its special structure, or it can be used to develop high-efficiency, low-toxicity and environmentally friendly pesticides, which can help the sustainable development of agriculture, which can not only effectively control pests and diseases, but also reduce the harm to the environment.
To sum up, N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide has important uses in many fields such as medicine, materials and agricultural chemistry, and is a compound that cannot be ignored in chemical research and industrial production.

The synthesis method of N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide has been around for a long time, and with the passage of time, the method has become more and more complicated and delicate. Today, I will describe its common methods in detail for those who are seeking knowledge.
First, use 4- (trifluoromethyl) pyridine-3-formic acid as the starting material. First, it is heated with sulfuryl chloride to convert it into the corresponding acid chloride. In this process, sulfuryl chloride is like a passionate messenger, carrying energy to help the reaction, activating the carboxyl group and making it easy to convert. After the acid chloride is formed, it reacts with cyanomethyl amine in the presence of a suitable base (such as triethylamine). Triethylamine acts as a stabilizing helmsman, regulating the reaction environment and guiding the smooth combination of acid chloride and cyanomethyl amine to form the target product N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide. Although this path step is not lengthy, it requires high control of the reaction conditions. The temperature and reagent ratio need to be precisely pinched to obtain satisfactory yields.
Second, 4 - (trifluoromethyl) pyridine-3-formonitrile is used as the starting material. It is hydrolyzed under mild conditions to form 4- (trifluoromethyl) pyridine-3-formamide. When hydrolyzed, it is like a spring breeze, and water molecules gently intervene to quietly convert the nitrile group into an amide group. Then, it reacts with halogenated acetonitrile under the catalysis of a base. The base is like a key here, opening the door of the reaction, prompting the halogen atom of halogenated acetonitrile to leave and connect with the nitrogen atom of the amide group, thereby constructing the structure of N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide. This method requires slightly less equipment, but it is not easy to optimize the conditions for hydrolysis and subsequent substitution reactions. Careful study is required to make each step of the reaction proceed smoothly.
Third, using suitable pyridine derivatives as raw materials, the target structure is constructed through a multi-step reaction. The pyridine ring is first modified by introducing necessary groups such as trifluoromethyl and carboxyl groups, and then gradually converted into corresponding amides, and finally cyanomethyl groups. Although this approach has many steps, it can flexibly cope with the characteristics of different raw materials, and the requirements for raw material selection are relatively broad. However, due to its complex steps, the reaction process is like a precise chess game. Every step needs to be careful to ensure that the reaction evolves in the expected direction in order to obtain a pure target product.

N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide is one of the organic compounds. Its physical properties are particularly important, and it is related to the characteristics and applications of this compound.
First of all, its properties are at room temperature, or white to off-white solid, like powder or crystal, uniform and delicate, and it is quite regular in appearance. This form is easy to store and use, and reflects the order of its molecular arrangement.
As for the melting point, this compound has a specific melting point range. After precise determination, it is between about [specific melting point range]. Melting point is an inherent property of a substance, which is like a human fingerprint. It can be used to identify its purity and provide key parameters for subsequent synthesis, separation and application steps. When the temperature rises to the melting point, the force between molecules weakens, and the solid state gradually melts into a liquid state. The change of the physical state highlights the change of its intrinsic structure.
Solubility is also an important property. In common organic solvents, such as methanol, ethanol, dichloromethane, etc., this compound exhibits different solubility properties. In methanol and ethanol, or with a certain solubility, a uniform and stable solution can be formed. This is because hydrogen bonds or other weak interactions can be formed between methanol, ethanol and the compound to promote their dispersion. In water, its solubility is relatively low, due to the fact that there are few hydrophilic groups in the molecular structure, and the force between it and water molecules is weak. This difference in solubility is of great significance in the selection of solvents for drug research and development and chemical synthesis.
In addition, the density of this compound is also one of its physical properties. Although the exact value needs to be determined by precision instruments, it can be seen that its density reflects the compactness of molecular stacking and is related to other physical properties. It is indispensable for industrial production in material measurement and reaction system design.
In summary, the physical properties of N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide, such as properties, melting point, solubility and density, are independent of each other, which lays a solid foundation for in-depth exploration of the chemical behavior of this compound and expansion of its application field.

I don't know the market price of "N- (cyanomethyl) -4- (trifluoromethyl) pyridine-3-formamide" as you said. This unusually easy-to-obtain material may be a special chemical raw material, a pharmaceutical intermediate, etc. Its price may vary depending on quality, purity, supply and demand, origin, and manufacturer.
If it is of high purity, used in fine chemical or pharmaceutical research and development, the price may be high. In the chemical raw material market, for ordinary purity, the price may vary according to the batch size. If the batch is large, the unit price may be slightly lower, and if the batch is small, the unit price may be higher.
However, I have not personally touched the market of this specific product, so it is difficult to determine its price. For details, you can consult chemical raw material distributors, traders, or find relevant quotation information on professional chemical trading platforms and information websites, or contact the manufacturer of this product to ask what the price is.