N-BOC-3-AMINO-4-PYRIDINE CARBOXYALDEHYDE

N-BOC-3-amino-4-pyridinal formaldehyde is a crucial compound in the field of organic synthesis. It has a wide range of uses and has made great contributions to the field of medicinal chemistry. Because medical research and development often requires the construction of complex molecular structures with specific biological activities, N-BOC-3-amino-4-pyridinal formaldehyde acts as a key starting material or intermediate.
When synthesizing drug molecules containing pyridine structure, this compound can use its amino and aldehyde reactivity to react ingeniously with many reagents to build a specific chemical skeleton. For example, amino groups can be acylated with carboxylic acids, anhydrides, etc., while aldehyde groups can participate in condensation reactions, such as generating Schiff bases with amines, or condensing with active methylene compounds, thereby introducing different substituents, so as to achieve precise regulation of the target molecular structure to meet the needs of drug interaction with specific biological targets.
In addition, in the field of materials science, N-BOC-3-amino-4-pyridine formaldehyde also shows unique value. Researchers can introduce it into the synthesis process of polymer materials through its reactivity. For example, by reacting with polymer monomers containing specific functional groups, the pyridine structure is integrated into the polymer chain, endowing the material with unique optical, electrical or chemical properties, such as enhancing the fluorescent properties of the material, improving its adsorption or sensing capabilities for specific substances, etc., opening up a broad path for the creation of new functional materials.

There are various ways to synthesize N-BOC-3-amino-4-pyridyl formaldehyde. First, it can be started from 4-pyridyl formaldehyde. First, the 3-position amino group is protected with an appropriate protecting group, and the BOC protecting group is often used. Here, 4-pyridyl formaldehyde and BOC anhydride are reacted in a suitable base, such as triethylamine, in a suitable solvent, such as dichloromethane. The alkali can promote the reaction of BOC anhydride with the 3-position amino group of pyridine formaldehyde to form a BOC-protected product, namely N-BOC-3-amino-4-pyridine formaldehyde. This process requires attention to the control of reaction temperature and time. Generally, the temperature is controlled between 0 ° C and room temperature, and the reaction is carried out for several hours to achieve a higher yield.
Second, 3-amino-4-pyridine carboxylic acid can be started. First, the carboxyl group is converted into an aldehyde group, which can be reduced by a method, such as treatment with reducing agents such as lithium aluminum hydride or sodium borohydride, to reduce the carboxyl group to an aldehyde group. However, the activity of lithium aluminum hydride is very high, and the operation needs to be done with caution under anhydrous and oxygen-free conditions. After the aldehyde group is formed, the amino group is protected by BOC anhydride, and the target product can also be obtained by reacting in a suitable solvent under alkali catalysis.
Or it can be constructed by multi-step reaction of other compounds containing pyridine rings. First, the amino precursor is introduced into the 3-position of the pyridine ring through substitution reaction, and the group that can be converted into an aldehyde group is introduced into the 4-position. After a series of reactions, such as oxidation, reduction, protection, etc., the goal is gradually achieved to synthesize N-BOC-3-amino-4-pyridinaldehyde. Although there are many steps in this path, it can be selected according to the availability of raw materials and the convenience of reaction conditions.

N - BOC - 3 - AMINO - 4 - PYRIDINE + CARBOXYALDEHYDE, that is, N - tert-butoxycarbonyl - 3 - amino - 4 - pyridyl formaldehyde, this physical property is particularly important, related to its performance and application in various reactions.
Looking at its physical properties, under normal conditions, or as a solid state, it is mostly white to white crystalline powder appearance, which is conducive to storage and use. Its melting point is also an important physical property. After accurate measurement, the melting point is in a specific temperature range, which is the key basis for identification and purity determination. And its solubility varies in common organic solvents. It exhibits good solubility in some organic solvents such as dichloromethane, N, N-dimethylformamide, while its solubility in water is relatively low. This difference in solubility is of great significance in separation, purification and reaction medium selection.
When it comes to chemical properties, the aldehyde group activity in the molecule is very high, and it is very easy to participate in many classical organic reactions, such as nucleophilic addition reactions with nucleophiles, forming new carbon-carbon or carbon-hetero bonds. This property makes it play a key role in the construction of complex organic molecular structures. The amino group is regulated by the action of the BOC protecting group. Under specific conditions, the BOC protecting group can be selectively removed, and then the amino group is released to participate in subsequent coupling, condensation and other reactions. As a conjugate system, the pyridine ring endows the molecule with a certain electronic effect and stability, affects the activity of peripheral functional groups, and can also act as a ligand to coordinate with metal ions, expanding its application in the field of metal organic chemistry.

I don't know what the price range of "N - BOC - 3 - AMINO - 4 - PYRIDINE + CARBOXYALDEHYDE" is in the market. The price of such things often changes for many reasons.
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N - BOC - 3 - AMINO - 4 - PYRIDINE CARBOXYALDEHYDE is one of the organic compounds. Its storage conditions are crucial and related to the stability and quality of this substance.
This substance should be stored in a cool and dry place, away from high temperature and humidity. High temperature can easily cause changes in its molecular structure and damage its chemical properties; humid environment may cause it to hydrolyze or react adversely with water vapor.
Furthermore, keep away from ignition sources and oxidants. Because of its certain chemical activity, it may react violently in case of fire or oxidants, causing the risk of combustion or even explosion.
When storing, it should be placed in a sealed container to prevent contact with air. Oxygen, carbon dioxide and other components in the air, or chemically react with the compound, causing it to deteriorate.
After taking it, be sure to seal the container in time and return to the original storage environment. In this way, N-BOC-3-AMINO-4-PYRIDINE CARBOXYALDEHYDE can maintain its inherent chemical properties for a certain period of time for subsequent experiments or production needs.