N Benzyl 2 3 Pyridinedicarboximide
pyridine pyrrole pyrazine piperidine piperazine

N-Benzyl- 2,3-pyridinedicarboximide

    Specifications

    HS Code

    145270

    Chemical Formula C15H12N2O2
    Molecular Weight 252.27 g/mol
    Appearance Solid (usually white or off - white powder)
    Melting Point Specific value would need experimental determination
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Value would need experimental determination
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
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    Frequently Asked Questions

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    What is the main use of N-Benzyl-2, 3-pyridinedicarboximide?
    N-Benzyl-2,3-pyridyldiformimide, this substance has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to assist in the synthesis of a variety of drugs. Due to its unique chemical structure, it can react ingeniously with many compounds to shape molecules with specific pharmacological activities, or involve the creation of anti-infection and anti-tumor drugs, making outstanding contributions to conquering diseases and protecting health.
    In the field of materials science, it also has outstanding performance. It can participate in the preparation of functional materials, giving materials unique electrical and optical properties. For example, by incorporating polymer materials through specific processes, or making materials exhibit excellent fluorescence properties, it has made a name for itself in the fields of optical sensors, Light Emitting Diode, etc., contributing to the development of material innovation.
    In the field of organic synthesis, it can be called a powerful "assistant". With its chemical activity, it participates in the construction of various complex organic molecules and expands the variety and structure of organic compounds. Synthetic chemists use this to realize novel reaction paths, create organic molecules with exquisite structures and unique properties, promote the frontier development of organic synthetic chemistry, and add pillars to the building of chemical science.
    What are the synthesis methods of N-Benzyl-2, 3-pyridinedicarboximide
    The method of synthesizing N-benzyl-2,3-pyridyldiformimide has followed many paths in the past. First, 2,3-pyridyldiformic anhydride and benzylamine are used as starting materials, and in suitable solvents, such as dichloromethane and N, N-dimethylformamide, a catalytic agent, such as 4-dimethylaminopyridine, is added to control temperature to make the two condensate. Among them, the acid anhydride bond of 2,3-pyridyldiformic anhydride meets the amino group of benzylamine, nucleophilic addition and then water loss, then N-benzyl-2,3-pyridyldiformimide is formed. After the reaction is completed, the purified product can be obtained by extraction and column chromatography.
    Second, first heat 2,3-pyridinedicarboxylic acid with sulfinyl chloride to make 2,3-pyridinedicarboxylic chloride. This step requires attention to the reaction temperature and time to prevent side reactions from occurring. Then, react with benzylamine and the newly prepared 2,3-pyridinedicarboxylic chloride in a base environment, such as the presence of triethylamine. The base can bind the acid and promote the reaction to the right. The reaction system can also be separated and refined to obtain the target product.
    Third, 2,3-pyridinedimethylnitrile is used as the starting material, first hydrolyzed to 2,3-pyridinediformamide, and then reacted with benzyl halide, such as benzyl bromide, under basic conditions, such as in an alcohol solution in the presence of potassium carbonate, and converted into N-benzyl-2,3-pyridinediformimide through Hoffman rearrangement and other processes. Each method has its own advantages and disadvantages, and it needs to be carefully selected according to many factors such as the availability of raw materials, the level of cost, and the advantages and disadvantages of yield.
    What are the physical properties of N-Benzyl-2, 3-pyridinedicarboximide
    N-Benzyl-2,3-pyridyldiformimide is a kind of organic compound. Its physical properties, first of all, in terms of appearance, under room temperature and pressure, are mostly white to light yellow crystalline powder, with fine appearance and uniform color.
    As for the melting point, it is about a specific temperature range, which is very critical in the identification and purification of the compound. The determination of its melting point can be an important basis for judging the purity and structure of the substance.
    In terms of solubility, this compound exhibits good solubility in common organic solvents, such as dichloromethane, chloroform and other halogenated hydrocarbon solvents, and can be mutually soluble with it to form a uniform solution. However, in water, its solubility is very small and almost insoluble. This difference in solubility is due to the characteristics of the functional groups contained in its molecular structure, including hydrophobic groups such as benzene ring and pyridine ring, which makes it difficult to dissolve in the aqueous phase with strong polarity, and more inclined to non-polar or weakly polar organic solvents.
    In addition, the density of the compound also has a certain value. Although the specific data needs to be accurately measured by experiments, its density characteristics are of important reference value in the material accounting, separation and purification of chemical production. Its packing compactness in the solid state can be seen from the density, which in turn affects its fluidity and dispersion under different process conditions.
    What are the chemical properties of N-Benzyl-2, 3-pyridinedicarboximide
    N-benzyl-2,3-pyridineformimide, this is an organic compound. Its chemical properties are unique, let me go through them in detail.
    This substance has a certain stability and can survive relatively stably at room temperature. In its structure, benzyl interacts with pyridineformimide partially, which has a great impact on its properties.
    From the perspective of reactivity, the benzyl ring on the benzyl group is rich in electrons, which is easy to initiate electrophilic substitution reactions. For example, when encountering electrophilic reagents, hydrogen atoms on the benzene ring can be replaced, which is one of its important reaction properties. The part of the pyridine ring, due to the existence of nitrogen atoms, is weakly basic and can react with acids to form corresponding salts.
    Furthermore, the imide structure in this compound cannot be ignored. Imide has a certain hydrolysis sensitivity. In a strong acid or alkali environment, under long-term action, imide bonds can be hydrolyzed to form corresponding carboxylic acids and amine compounds.
    In addition, due to the conjugated system in the molecule, N-benzyl-2,3-pyridinedicarbamide has certain optical properties, or it can be used in some photochemical fields. At the same time, its solubility also has characteristics. It has certain solubility in common organic solvents such as dichloromethane and chloroform, but poor solubility in water, which is related to the polarity of its molecules.
    What is the price range of N-Benzyl-2, 3-pyridinedicarboximide in the market?
    I don't know that N-Benzyl-2 3-pyridinedicarboximide in the market price range. However, if you want to know the price of this product, you can explore it from several places. First, ask chemical reagent suppliers. There are many such merchants in the city, which sell all kinds of chemical products, you can go there and ask the price of this compound. Or you can log in to its official website, search for the product, check its list price, and get an approximate price. Second, look at the online chemical trading platform. Nowadays, e-commerce is prosperous, and many chemicals are also sold online. Search for this product on such platforms, and you can see the quotations of different sellers. By comparing, you can know the price range. Third, refer to relevant academic literature and industry reports. Sometimes in literature or reports, some chemical price information will be mentioned, although it may not be accurate to N-Benzyl-2, 3-pyridinedicarboximide, but the price of the same compound may be obtained as a reference to infer the approximate range of its price. However, it should be noted that the price of chemical products often changes due to purity, output, market supply and demand, etc., so the exact price is subject to real-time inquiry.