N 4 6 Dimethoxypyrimidin 2 Yl Carbamoyl 3 2 2 2 Trifluoroethoxy Pyridine 2 Sulfonamide
pyridine pyrrole pyrazine piperidine piperazine

N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(2,2,2-trifluoroethoxy)pyridine-2-sulfonamide

    Specifications

    HS Code

    233135

    Chemical Name N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(2,2,2-trifluoroethoxy)pyridine-2-sulfonamide
    Molecular Formula C14H15F3N4O6S
    Molecular Weight 424.35
    Appearance Typically a solid (appearance can vary based on purity and production method)
    Melting Point Specific value would require experimental determination
    Solubility Solubility characteristics would depend on solvents; may have limited solubility in water but better solubility in some organic solvents
    Pka Values related to acidic or basic groups in the molecule would determine pKa, needs experimental measurement
    Logp Describes lipophilicity, experimental determination required
    Vapor Pressure Low vapor pressure expected for a solid compound, but exact value needs measurement
    Stability Stability can be affected by factors like temperature, light, and humidity

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    Frequently Asked Questions

    As a leading N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(2,2,2-trifluoroethoxy)pyridine-2-sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of N- [ (4,6-dimethoxypyrimidine-2-yl) aminoformyl] -3- (2,2,2-trifluoroethoxy) pyridine-2-sulfonamide
    This is an organic compound. If you want to know its chemical properties in detail, let me explain in detail.
    This compound contains a variety of groups, which have a great influence on its chemical properties. Among them (4,6-dimethoxycarbonyl-2-yl) aminoformyl group, the carbonyl group in this structure has a certain polarity and can participate in a variety of reactions. The carbon atom of the carbonyl group is partially positively charged and vulnerable to attack by nucleophiles. In case of nucleophilic hydroxyl groups, amino groups and other groups, nucleophilic addition reactions may occur, forming new chemical bonds, thereby changing the molecular structure and properties.
    Furthermore, 3- (2,2,2-trifluoroethoxy) benzoyl-2-thiazole group, the fluorine atom is extremely electronegative, and the introduction of trifluoroethoxy changes the electron cloud density in this area. Due to the electron-absorbing effect of fluorine atoms, this part affects the electron cloud distribution of the benzene ring connected to it, resulting in a decrease in the electron cloud density of the benzene ring. In the aromatic electrophilic substitution reaction, this structure is more difficult to react than benzene itself, and the substitution position may be different from that of the conventional benzene ring. At the same time, the thiazole ring also has a special electronic structure and reactivity. The nitrogen and sulfur atoms of the thiazole ring endow it with certain basic and nucleophilic properties, or can react with acids, halogenated hydrocarbons, etc. < Br >
    This compound may have certain chemical activity and can participate in various organic reactions such as addition and substitution. However, the specific reaction situation depends on the reaction conditions, such as temperature, solvent, catalyst, etc.
    What is the scope of application of N- [ (4,6-dimethoxypyrimidine-2-yl) aminoformyl] -3- (2,2,2-trifluoroethoxy) pyridine-2-sulfonamide
    N- [ (4,6-diethoxycarbonyl-2-aminoethyl) amino] -3- (2,2,2-trifluoroethoxy) benzene-2-formamide, this is an organic compound. Its application range is quite wide, and in the context of "Tiangong Kaiji", it may be discussed from the aspects of chemical raw materials, pharmaceutical synthesis, etc.
    In the field of chemical raw materials, such compounds may be used as monomers for the synthesis of polymer materials with special properties. Its unique molecular structure may endow polymer materials with special physical and chemical properties, such as improving material stability and heat resistance. As recorded in "Tiangong Kaiwu", the manufacture of various materials focuses on the influence of raw material characteristics on the finished product. The characteristics of this compound may play a key role in the creation of new materials.
    In the synthesis of medicine, it may have potential biological activity. Because it contains specific functional groups, it may interact with targets in organisms, so as to develop drugs for the treatment of specific diseases. Just like the research on the preparation of various drugs in "Tiangong Kaiwu", this compound may be appropriately modified and modified to become an effective pharmaceutical ingredient.
    However, its application is also restricted by many factors. On the one hand, the process of synthesizing this compound may be complex and costly, limiting its large-scale production and application. On the other hand, it is necessary to conduct in-depth research on its safety and biocompatibility to ensure that it has no adverse effects on the human body and the environment in practical applications, which is also in line with the concept of considering the advantages and disadvantages of material application in "Tiangong Kaiwu".
    What is the preparation method of N- [ (4,6-dimethoxypyrimidine-2-yl) aminoformyl] -3- (2,2,2-trifluoroethoxy) pyridine-2-sulfonamide
    To prepare N- [ (4,6-diethoxycarbonyl-2-yl) carbamoyl] -3- (2,2,2-trifluoroethoxy) benzene-2-sulfonamide, the method is as follows:
    First take an appropriate amount of 4,6-diethoxycarbonyl-2-aminobenzoic acid and place it in a clean reaction vessel. Add an appropriate amount of chlorination reagent, such as thionyl chloride, at a suitable temperature and stirring conditions to convert the carboxyl group to acid chloride. This process needs to pay attention to the control of the reaction temperature, not too high or too low. If it is too high, it is easy to cause side reactions, and if it is too low, the reaction rate is too slow.
    After the acid chloride is formed, cool down and slowly add 3- (2,2,2-trifluoroethoxy) -2-aminobenzenesulfonamide. At the same time, add an appropriate amount of acid binding agent, such as triethylamine, to neutralize the hydrogen chloride generated by the reaction, and promote the reaction to proceed in the positive direction. Keep stirring and react at a certain temperature for a period of time, so that the two can fully react to form an amide bond.
    After the reaction is completed, pour the reaction mixture into an appropriate amount of ice water, and solid precipitates. Filter, collect the solid, and wash it in sequence with an appropriate amount of water and organic solvent to remove impurities. After that, put the resulting solid in an oven and dry it at a suitable temperature to obtain a crude product.
    Crude product can be further purified by recrystallization. Select a suitable solvent, such as a mixed solvent of ethanol and water, dissolve the crude product, heat it until it is completely dissolved, and filter it hot to remove insoluble impurities. The filtrate is slowly cooled, and crystals are precipitated. Filtrate again, collect crystals, and dry to obtain pure N- [ (4,6-diethoxycarbonyl-2-yl) carbamoyl] -3- (2,2,2-trifluoroethoxy) benzene-2-sulfonamide. The whole preparation process requires strict control of reaction conditions and operation details to obtain high-purity products.
    What is the market prospect of N- [ (4,6-dimethoxypyrimidine-2-yl) carbamoyl] -3- (2,2,2-trifluoroethoxy) pyridine-2-sulfonamide?
    Nowadays, there is N- [ (4,6-diacetylbenzo-2-yl) aminoformylphenoxy] -3- (2,2,2-trifluoroethoxy) benzoic-2-ylbenzoic acid. Its market prospects are as follows:
    This compound has potential application value in many fields such as medicine and materials, so the market prospect is quite promising. In the field of medicine, with the in-depth study of disease mechanisms, the development of precision drugs targeting specific targets has received much attention. The unique structure of this compound may specifically bind to some disease-related targets, thus demonstrating good biological activity and pharmacological effects, providing a key opportunity for the creation of new drugs. In view of the urgent need for high-efficiency and low-toxicity drugs, if the drug based on this compound can be successfully developed, it is very likely to occupy a place in the market.
    In the field of materials, with the rapid development of science and technology, the demand for high-performance materials is increasing day by day. The special chemical structure of this compound may endow the material with unique physical and chemical properties, such as excellent optical and electrical properties, or good thermal stability and mechanical properties. With these characteristics, it may be applied to many high-end fields such as electronic devices and optical materials, meeting the needs of related industries for new materials, and then opening up a broad market space.
    However, its market development also faces certain challenges. First, the synthesis process of compounds may be more complex and the production cost is relatively high, which hinders large-scale production and marketing activities. Secondly, the development of new drugs requires a long and rigorous clinical trial process, which is time-consuming and laborious, and the success rate is not 100%. In terms of material application, it is also necessary to study its compatibility with other materials and large-scale preparation processes.
    Overall, N- [ (4,6-diacetylbenzo-2-yl) aminoformylphenoxy] -3- (2,2,2-trifluoroethoxy) benzoic-2-ylbenzoic acid has broad market prospects, but it also needs to overcome many technical and cost problems in order to fully realize its commercial value.
    N- [ (4,6-dimethoxypyrimidine-2-yl) aminoformyl] -3- (2,2,2-trifluoroethoxy) pyridine-2-sulfonamide What are the precautions during use?
    N- [ (4,6-diacetoxybenzene-2-yl) carbamoyl] -3- (2,2,2-trifluoroethoxy) benzene-2-sulfonamide is a delicate chemical synthesis product. During its use, many precautions need to be taken with caution.
    First, safety protection is of paramount importance. This substance may be toxic and irritating to a certain extent. When coming into contact, be sure to wear complete protective equipment, such as protective clothing, gloves and goggles, to prevent it from contacting the skin and eyes and causing damage. In case of accidental contact, rinse with plenty of water immediately and seek medical assistance according to the specific situation.
    Second, the operating environment needs to be paid special attention. The operation should be carried out in a well-ventilated place to avoid the accumulation of volatile gases in the air, which can cause the operator to inhale and damage health. At the same time, the operation area should be kept away from fire and heat sources, which may pose a risk of flammability or thermal decomposition, causing serious accidents such as fire or explosion.
    Third, storage conditions should not be ignored. It should be stored in a cool, dry and ventilated place, away from oxidants and acid and alkaline substances. Due to its chemical properties or causing them to react with these substances, the product will deteriorate or cause danger. Storage containers should also be well sealed to prevent them from getting wet or reacting with air components.
    Fourth, during use, strictly follow the established operating procedures and dosage requirements. Do not change the method and dosage without authorization, so as not to affect the effect or cause safety problems. After use, properly dispose of the remaining products and waste, do not discard at will, and should be disposed of in accordance with relevant environmental regulations to prevent pollution to the environment.