As a leading N-(4,6-DIMETHOXY-2-PYRIMIDINYLAMINOCARBONYL)-3-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of N- (4,6-dimethoxy-2-pyrimidinylcarbamoyl) -3- (trifluoromethyl) -2-pyridinesulfonamide?
This is a question about the structure of an organic compound. This compound contains nitrogen and has a specific substituent group. "4,6-dihydroxy-2-mercapto-hydroxyethylcyano", it can be seen that this part contains two hydroxyl groups and one thiol group, and has a specific connection method. "3 - (trifluoromethyl) -2 - shows the chemical structure of cyanourea to it", indicating that there are also trifluoromethyl substituted in a specific position.
From the perspective of this organic compound, the structure of this organic compound is quite complex, with nitrogen atoms as the core and different groups connected around it. The hydroxyl group at the 4,6 position can make the molecule have a certain hydrophilicity and can participate in the formation of hydrogen bonds, which has a great impact on the physical and chemical properties of the compound. 2-Mercapto-ethoxy-ethyl cyano, of which the mercapto group has high chemical activity and is easy to participate in redox and other reactions; the cyano group has a strong polarity, which affects the molecular dipole moment and reactivity. The introduction of trifluoromethyl, due to the large electronegativity of fluorine atoms, changes the distribution of molecular electron clouds, and affects the stability and lipophilicity of the compound.
Overall, the characteristics of the chemical structure of this compound determine that it may have unique uses in organic synthesis, medicinal chemistry and other fields. The interaction of its different groups endows the compound with diverse chemical properties, or can be used to develop new drugs, materials, etc. However, the specific application still depends on the in-depth study of its properties and reactivity.
What are the main uses of N- (4,6-dimethoxy-2-pyrimidinylcarbamoyl) -3- (trifluoromethyl) -2-pyridinesulfonamide?
N- (4,6 -diethoxy-2 -carboxyloxyethylbenzyl) -3- (trifluoromethyl) -2 -benzyl urea to it, its main use is the preparation of medicine, pesticides and other organic synthesis intermediates.
This compound can be used as an important intermediate in pharmaceutical creation, through chemical modification and transformation to construct molecular structures with specific physiological activities. For example, in the development of some new antibacterial drugs, this substance can participate in key reaction steps by virtue of its special chemical structure, and react with other reagents to generate compounds that have inhibitory or killing effects on specific bacteria. < Br >
also plays a key role in the field of pesticides. It can be used as a starting material or an important intermediate for the synthesis of high-efficiency and low-toxicity pesticides. By rationally designing the reaction route and combining it with other functional groups, a pesticide variety with high-efficiency control effect on crop pests and environmental friendliness can be created.
Because its structure contains specific functional groups, it is endowed with specific reactivity and selectivity. It is widely used and studied in the field of organic synthetic chemistry, providing a key basis and effective way for the development of new drugs and pesticides.
What are the production methods of N- (4,6-dimethoxy-2-pyrimidinylcarbamoyl) -3- (trifluoromethyl) -2-pyridinesulfonamide?
To prepare N- (4,6-dihydroxy-2-carboxyloxybenzyl) -3- (trifluoromethyl) -2 to express benzyl urea to it, the method is as follows:
First, the corresponding starting materials need to be prepared, such as compounds containing 4,6-dihydroxy-2-carboxyl groups, reagents containing trifluoromethyl groups, and raw materials that can form benzyl urea structures.
One method can first make compounds containing 4,6-dihydroxy-2-carboxyl groups react with appropriate halobenzyl to form 4,6-dihydroxy-2-carboxyloxybenzyl intermediates. In this step, suitable bases and reaction solvents need to be selected to promote the progress of nucleophilic substitution reactions. If potassium carbonate is used as a base, acetonitrile is used as a solvent, and heating is refluxed to make the two fully react, the intermediate can be obtained by separation and purification.
Then, the intermediate is reacted with isocyanate containing trifluoromethyl. This reaction is usually carried out under mild conditions, such as room temperature or slight heating, in an inert solvent such as dichloromethane. The two can be added to form the target product N- (4,6-dihydroxy-2-carboxyloxybenzyl) -3- (trifluoromethyl) -2-benzyl urea. After the reaction is completed, the product is purified by regular extraction, column chromatography and other means.
Another method can first prepare amines containing trifluoromethyl, react with phosgene or its substitutes to form corresponding isocyanates, and directly react with benzyl alcohol derivatives containing 4,6-dihydroxy-2-carboxyl without separation. This "one-pot method" can simplify the operation steps, reduce the loss of intermediate separation, and improve the reaction efficiency. However, precise control of the reaction conditions is required to ensure the orderly progress of each step of the reaction.
To prepare this compound, the advantages and disadvantages of each method should be weighed according to the actual situation, and the most suitable synthesis path should be selected to achieve the purpose of efficient and high-purity preparation.
What are the safety and toxicity of N- (4,6-dimethoxy-2-pyrimidinylcarbamoyl) -3- (trifluoromethyl) -2-pyridinesulfonamide?
N- (4,6-diacetyl-2-tert-butylchitroacetamido) -3- (trifluoromethyl) -2 shows the safety and toxicity of aniline to it? The safety and toxicity of this substance are very critical, and it is related to many practical application scenarios.
According to the concept of "Tiangong Kaiwu", all material properties should be comprehensively reviewed. For this compound, from the perspective of chemical structure, it contains complex groups. The existence of tert-butyl may affect the molecular spatial configuration and stability, while trifluoromethyl has strong electronegativity, or endows the molecule with special physical and chemical properties. < Br >
In terms of safety, due to the presence of a variety of special groups, there may be uncertain factors when interacting with organisms. Its degradation pathways and products in the environment also need to be explored in detail to prevent environmental pollution. If it enters ecosystems such as water bodies and soils, it may have a chain effect on biological communities.
In terms of toxicity, due to its structural complexity, it may have different degrees of effect on organisms. Or interfere with normal biochemical reactions in organisms, affect cell metabolism, enzyme activity, etc. May cause damage to important organs such as animal nervous system, liver, kidney, etc. However, the exact toxicity needs to be determined by rigorous experiments, such as acute toxicity experiments, which can detect the lethal dose to experimental animals in a short period of time; chronic toxicity experiments, which can detect the potential harm to the body under long-term exposure.
Overall, although it is difficult to fully understand the safety and toxicity of this substance based on its structure, it is clear that it needs to be treated with scientific caution based on chemical principles and experience of similar structural substances. Systematic experimental studies can clarify its exact safety and toxicity, and provide a solid basis for its rational application and risk prevention and control.
What is the market prospect of N- (4,6-dimethoxy-2-pyrimidinylcarbamoyl) -3- (trifluoromethyl) -2-pyridinesulfonamide?
(The following answer is in the classical Chinese style, assuming that the substance is a relatively novel thing in the world, and the "market prospect" refers to its market-related external performance, public reaction, etc.)
There is a thing today, named N- (4,6-diethoxy-2-carboxylethoxy-ethoxy-benzyl) -3- (trifluoromethyl) -2 - shows benzamide to it. This substance is unique among all things.
Looking at the market prospect, when it first appeared, everyone was amazed. The scholars of the Fang family, upon hearing its name, explored its nature, and wanted to investigate its reasons one after another. Among merchants, it is also said that it has extraordinary uses, or can open up new paths in various industries.
People in the city who are good at observing business opportunities have regarded this as a potential benefit. However, there are also skeptics, because the nature of the new thing is not clear, it is unknown what effect it can have in practice.
When it first entered the market, its price was undetermined, and it fluctuated. It can be seen that everyone was hesitant to wait and see. Those who are bold are the first to introduce it to try it out. If its effect is significant, then people will flock to it and compete for it, and the price should also rise accordingly, and the market may become a state of competition.
And if its effect does not meet the expectations, it may be left out in the cold, hidden in the city, waiting for those who can explore its secrets again, in order to turn around. Therefore, the prospect of the city is like the moon in the clouds, hazy and waiting to be seen. Although the prospect is uncertain, its new nature has attracted the attention of the world. With time, it may be able to show its unique style in the city and become a weather.