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What is the chemical structure of N- [4- (1-cyanocyclopentyl) phenyl] -2- [ (4-pyridylmethyl) amino] pyridine-3-formamide
This is a question about the chemical structure of N- [4- (1-benzylcyclopentyl) phenyl] -2- [ (4-pyridylmethyl) amino] pyridine-3-acetamide. To solve this question, it is necessary to follow the knowledge of chemistry and the method of related analysis.
First look at the structure of each part of this compound. "N -" indicates that this is a group containing a nitrogen atom and is in a specific position in the nomenclature. "[ 4 - (1 - benzylcyclopentyl) phenyl] ", this part consists of phenyl and 4- (1 - benzylcyclopentyl) connected thereto, benzyl is benzyl, cyclopentyl is a five-membered carbon ring, and the two are connected and connected to the 4-position of phenyl." 2 - [ (4 - pyridylmethyl) amino] pyridine ", pyridine is a nitrogen-containing hexaadic heterocycle, where the 2-position of pyridine is connected with [ (4 - pyridylmethyl) amino], that is, 4 - pyridylmethyl is connected to the amino group and then connected to the 2-position of pyridine." 3-Acetamide ", indicating that the 3-position of pyridine is connected with an acetamide group, and acetamide is a structure in which an acetyl group is connected to an amino group.
In summary, this compound has a complex structure and is formed by connecting multiple parts of specific groups in a specific way. Its chemical structure is determined by the position and connection relationship of each group, which endows the compound with specific chemical properties and reactivity.
What is the main use of N- [4- (1-cyanocyclopentyl) phenyl] -2- [ (4-pyridylmethyl) amino] pyridine-3-formamide
N- [4- (1 -benzylcyclopentyl) phenyl] -2- [ (4 -methoxybenzyl) amino] -3 -methylpyridine is a class of organic compounds. This compound has important uses in the field of medicinal chemistry.
It is often used as a key intermediate in the process of drug development. For example, in the creation of some new anti-tumor drugs, the compound can specifically bind to specific targets in tumor cells due to its unique chemical structure. The growth and proliferation of tumor cells depend on many key proteins and signaling pathways. This compound can precisely act on these targets, interfere with the normal physiological activities of tumor cells, and then inhibit the growth and spread of tumor cells.
In the field of drug research for neurological diseases, it also has room for expression. The pathogenesis of neurological diseases is complex, involving many aspects such as neurotransmitter imbalance and nerve cell damage. This compound can regulate the release and transmission of neurotransmitters, or promote the repair and regeneration of nerve cells, bringing new opportunities for the treatment of neurological diseases such as Parkinson's disease and Alzheimer's disease.
It is also useful in the field of pesticide chemistry. Pesticides with high insecticidal and bactericidal activities can be designed and synthesized. By interfering with specific physiological processes in the body of pests, effective control of crop diseases and pests is achieved, which helps agricultural production improve yield and quality, and ensures the supply and safety of agricultural products.
What is the market outlook for N- [4- (1-cyanocyclopentyl) phenyl] -2- [ (4-pyridylmethyl) amino] pyridine-3-formamide?
There is a question today: What is the market prospect of N - [4- (1-benzylcyclohexyl) phenyl] -2- [ (4-p-toluene ethyl) amino] p-toluene-3-acetamide? I will imitate "Tiangong Kaiwu" and answer it in an ancient way.
Look at this compound, its structure is exquisite, and it seems to be a combination of wonders. However, if you want to understand its market prospect, you should consider various factors.
First, look at its use. If this compound is used in the field of medicine, it can be a good medicine for treating diseases, or can solve the suffering of patients, such as a golden pill for helping the world, there must be a wide demand. < Br >
Second, it depends on the industrial application. If it is used in chemical production, it can be used as an efficient auxiliary agent, improve the process, and increase the quality. If it is a weapon of good craftsmen, the industry must compete for it, and its city should also prosper.
Third, it is related to the cost of research and development and the difficulty of production. If the investment in research and development is huge, and the production is very difficult, such as pearl harvesting in the deep sea and cinnamon harvesting in the moon palace, the cost will be high, and the price will be expensive. Although it is useful, if the price is high, there will be few applicants. Only by reducing its cost and making it easier to produce can it be widely used and expand its market.
Fourth, look at peer competition. In today's world, science and technology are changing day by day, and similar things may emerge in an endless stream. If this compound does not have unique strengths and is difficult to stand in the world, it is like a drop in the ocean, and it is obsolete to everyone, the market will be worrying. It must have something exceptional, such as standing out from the crowd, in order to stand out and occupy a seat in the market.
In summary, the market prospect of N - [4- (1-benzylcyclohexyl) phenyl] -2 - [ (4-toluene-ethyl) amino] p-toluene-3-acetamide cannot be cut off. If you make good use of its strengths, solve its problems, respond to the needs of the market, and avoid the front of competition, you are expected to become a treasure of the market and have a bright future; otherwise, you will be afraid of passing by like a meteor, fleeting.
What are the preparation methods of N- [4- (1-cyanocyclopentyl) phenyl] -2- [ (4-pyridylmethyl) amino] pyridine-3-formamide
To prepare N - [4 - (1 - cyclohexylphenyl) phenyl] - 2 - [ (4 - biphenyl) amino] biphenyl - 3 - benzoic acid, the preparation method is as follows:
First, through the halogenation reaction, select a suitable halogenating agent, such as bromine or chlorine halogenating reagent, in the appropriate reaction conditions and solvent system, the starting material is introduced into the halogen atom at a specific position to create an active check point for the subsequent reaction. This step requires precise control of the reaction temperature, time and amount of halogenating agent to avoid excessive halogenation. < Br >
Then a palladium-catalyzed coupling reaction is carried out. The halogen-containing raw materials are coupled with the corresponding organometallic reagents, such as organoboronic acid or organozinc reagents, under the action of palladium catalysts, in an alkaline environment. The activity of palladium catalysts, the type and amount of bases, and the choice of reaction solvent are all crucial in this process, which directly affect the coupling efficiency and product purity.
For the construction of cyclohexyl moieties, the hydrogenation of olefins can be considered. If there is a suitable alkenyl structure in the raw material, in the presence of suitable catalysts such as platinum, palladium or nickel, hydrogen is introduced for hydrogenation to form a stable cyclohexyl group. The pressure, temperature and catalyst activity of the hydrogenation reaction need to be carefully regulated to ensure the smooth progress of the reaction and avoid excessive hydrogenation or other side reactions.
At the same time, in the synthesis process, the separation and purification of intermediates are essential. Conventional methods such as column chromatography and recrystallization can be used to ensure the purity of intermediates and lay a good foundation for subsequent reactions. After each step of the reaction, the structure and purity of the product need to be confirmed by nuclear magnetic resonance, mass spectrometry and other analytical means, so as to adjust the reaction conditions in time to ensure the final preparation of high purity N- [4- (1-cyclohexylphenyl) phenyl] -2 - [ (4-biphenyl) amino] biphenyl-3-benzoic acid.
What are the related pharmacological activities of N- [4- (1-cyanocyclopentyl) phenyl] -2- [ (4-pyridylmethyl) amino] pyridine-3-formamide
The pharmacological activities related to N - [4- (1-benzylcyclohexyl) phenyl] -2 - [ (4-p-toluene ethyl) amino] p-toluene-3-acetamide are as follows:
The structure of this compound is relatively complex. From the general connection between structure and pharmacological activity, the phenyl, benzyl, cyclohexyl and other groups contained in it may have various effects on its pharmacological activity. Phenyl often imparts a certain lipid solubility to the compound, which helps it to penetrate the biofilm and enter the cell to play a role. The presence of benzyl groups may enhance the hydrophobic interaction of compounds with specific biological targets, affecting their ability to bind to biological macromolecules such as proteins and enzymes.
While acetamide groups are common in many drug molecules, they may participate in the formation of hydrogen bonds and interact specifically with biological targets, thereby regulating related biological processes. For the specific substituents to which the compound is attached, such as p-toluene, etc., its electronic properties and spatial structure may be further fine-tuned, affecting its affinity and selectivity with the target.
However, it is difficult to accurately determine its specific pharmacological activity only from structural inference. In general, compounds with similar structures may have multiple potential activities. In neurological studies, such compounds containing aryl structures may exhibit neuroregulatory activities, such as affecting the release of neurotransmitters or receptor binding, and may be used to treat neurological diseases such as anxiety and depression. In the field of anti-tumor, complex aryl structures may interfere with the signaling pathways of tumor cells and inhibit the proliferation and metastasis of tumor cells. However, to know its pharmacological activity, it is necessary to conduct rigorous experimental studies, such as cell experiments, animal experiments, and subsequent clinical trials, to conduct a comprehensive and in-depth evaluation.