N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide bis(phosphate)

This is to explore the chemical structure of N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) -2- [ (p-toluene) amino] p-toluenesulfonamide bis (oxalate). The structure of this compound is slightly more complex, so let me explain it in detail.
The first view of the N atomic connection part is 3,3-dimethyl-2,3-dihydro-1H-indole-6-yl. This indole structure has two methyl groups at the 3rd position, and the N atom is connected at the 6th position. This structure endows the compound with a specific spatial configuration and electron cloud distribution, which has a great impact on its physical and chemical properties.
Looking at the 2 - [ (p-toluene) amino] part, the p-toluene group is connected to the main body through the amino group. The p-toluene group has a donor electron effect, and the amino group is also an active check point. The connection of the two can adjust the molecular electron cloud density and reactivity.
As for the p-toluenesulfonamide part, the structure of the sulfonamide is stable, and the modification of the p-toluenyl group adds characteristics. It is connected to the first two parts to build the basic skeleton of the compound. < Br >
And bis (oxalate) is connected to the above main body. Oxalate can be combined by coordination bonds and other means to change the overall charge distribution and coordination ability of the compound. This bis (oxalate) part may affect the solubility, stability and interaction of the compound with other substances.
In summary, the structure of the compound is composed of multiple parts, and each part affects each other to determine its unique physicochemical properties and reactivity.

N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) -2 - [ (p-toluene-4-yl) amino] p-toluene-3-formamidobis (lactic acid) This chemical substance has various uses in different fields.
In the field of pharmaceutical research and development, due to its unique chemical structure or specific biological activities, it can target specific targets in the body. For example, it can bind to specific proteins, enzymes or receptors to affect cell signaling pathways. Like some indole-containing compounds, it can regulate cell growth and differentiation, so this substance may have potential value in the research and development of anti-cancer and anti-inflammatory drugs, and is expected to bring new opportunities for the treatment of related diseases.
In the field of materials science, the substance may endow the material with special properties due to its structural properties. For example, it can improve the stability, plasticity or conductivity of the material. When synthesizing new polymer materials, introducing them as functional monomers can make the material have unique physical and chemical properties and meet the needs of high-performance materials in aerospace, electronic equipment and other fields.
In the field of organic synthetic chemistry, this compound can act as a key intermediate. With the active groups in its structure, through various chemical reactions, more compounds with complex structures and different functions can be derived. Organic chemists can design and synthesize organic molecules with novel structures and properties, expand the variety and application range of organic compounds, and provide a new direction and material basis for the development of organic synthetic chemistry.

This is a complex drug named N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) 2- [ (p-toluene) amino] p-toluenesulfonic acid bis (lactic acid) salt. Its many side effects cannot be ignored.
First, it may disturb the flow of qi and blood in the human body, causing dizziness. Qi and blood are not smooth, the clear sun does not rise, the leader is disnourished, and the head feels dizzy, the vision rotates, and the path is unstable, which affects the end of daily travel.
Second, it is easy to mess up the viscera and transport. The spleen and stomach bear the brunt, or the appearance of nausea and vomiting. The spleen and stomach are the foundation of the day after tomorrow and mainly transport water and valleys. This medicine disturbs the spleen and stomach, and the stomach qi is reversed, so it is nauseous and vomiting, and the diet is difficult, which affects the nutrient intake of the body.
Third, the qi and blood in the meridians are also hindered. Or lead to numbness of the limbs. The meridians are the channels for the operation of qi and blood. The effect of medicine makes the meridians paralyzed and blocked, and the qi and blood cannot reach the ends of the limbs. The limbs are lost in nourishment, so there is a feeling of numbness, and the movement is also constrained.
Fourth, it also affects the mood, or causes upheaval. The mind dominates the gods, the bias of medicine, disturbs the mind, makes people emotionally restless, restless, and difficult to meditate, affecting people's mental state and daily thoughts.
Those who use this medicine should carefully observe the changes in the body, and if there is any discomfort, seek a good doctor immediately to ensure their well-being.

N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) 2- [ (p-toluene-4-yl) amino] p-toluenesulfonamide bis (oxalic acid) is in the market, and its market conditions are as follows:
This compound has a specific supply and demand situation in today's pharmaceutical market. On the supply side, due to the multi-step reaction involved in the synthesis process and strict control of reaction conditions, such as temperature, pH and the precise use of catalysts, the production scale is limited. Some workshops are difficult to produce sufficient and stable quality products due to lack of technology. Therefore, the supply in the market is not full, and it is often tight.
On the demand side, due to its emergence in the field of pharmaceutical research and development, especially in the research and development process of new anti-tumor drugs and drugs for the treatment of nervous system diseases, it shows potential activity and pharmacological effects, which has attracted many pharmaceutical companies and scientific research institutions to compete for purchase. R & D institutions are on the rise in demand for it, intending to break through the bottleneck of existing drug research and development.
The market price is also influenced by supply and demand. Due to limited supply, demand is booming, and its price remains high. However, considering the important value of this compound in scientific research and exploration, although many demand parties feel the pressure of price, they are still willing to invest in purchase to promote the progress of their own R & D projects.
Overall, N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) 2- [ (p-toluene-4-yl) amino] p-toluenesulfonamide bis (oxalic acid) is in the market, which is in a situation of tight supply, strong demand and high price, and occupies a very key position in the pharmaceutical R & D raw material market.

To prepare N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) -2- [ (p-toluene) amino] p-toluenesulfonamide and bis (oxalate) ester, the method is as follows:
First take N- (3,3-dimethyl-2,3-dihydro-1H-indole-6-yl) -2- [ (p-toluenesulfonamide) amino] p-toluenesulfonamide, which can be prepared by reacting the corresponding indole derivative with p-toluenesulfonyl chloride in a suitable base, such as potassium carbonate, in a suitable solvent, such as dichloromethane or N, N-dimethylformamide, at a mild temperature, such as 0 ° C to room temperature. The reaction requires sufficient stirring to fully contact the raw materials. When the reaction is complete, the product is purified by conventional post-processing steps such as extraction, washing, drying, and column chromatography.
The preparation of bis (oxalic acid) esters can be prepared by oxalic acid and corresponding alcohols under acid catalysis, such as concentrated sulfuric acid or p-toluenesulfonic acid, in an appropriate solvent, such as toluene, heated and refluxed for esterification. The reaction process requires a water separator to remove water to promote the positive progress of the reaction. After the reaction is completed, cool, neutralize the acid, separate the liquid, and the organic phase is dried and then distilled under reduced pressure to collect the corresponding fraction to obtain the bis (oxalic acid) ester product.
When preparing these two, attention should be paid to the precise control of reaction conditions, including temperature, pH, raw material ratio, etc., and the post-processing steps are also crucial, which are related to the purity and yield of the product. The operation process should follow the safety regulations of chemical experiments to ensure the safe and orderly conduct of experiments.