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What is the chemical structure of N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indol-6-yl) pyridine-4-carboxamide
This is a question about the chemical structure of the compound "N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide". This compound has a complex structure and is composed of two key structural units, pyridine and benzo [cd] indole.
The pyridine part is a nitrogen-containing hexagonal aromatic ring, which is common in many drugs and bioactive molecules and has unique electronic properties and reactivity. Its 4-position connection formamide group, this group contains carbonyl and amino groups, can participate in hydrogen bonding, and is crucial in molecular recognition and biological activity display.
Benzo [cd] indole is partially fused from benzene ring and indole ring. The first position has ethyl substitution, which changes the molecular spatial structure and lipophilicity. The second position is carbonyl, which enhances molecular polarity and reactivity. The conjugate structure of this fused ring system is large, which endows the molecule with specific optical and electronic properties.
Overall, the compound fuses the structure of pyridine and benzo [cd] indole, and each part works synergistically, or endows it with diverse biological activities and physicochemical properties, which may have potential application value in drug development, materials science and other fields.
What are the main uses of N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indol-6-yl) pyridine-4-carboxamide
N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide, an organic compound. It has a wide range of uses and is of great significance in the field of pharmaceutical research and development.
First, in the study of anti-tumor drugs, many compounds containing this structure have shown potential anti-tumor activity. It may inhibit tumor cell proliferation and induce apoptosis by inhibiting specific signaling pathways of tumor cells, bringing new hope for the fight against cancer. For example, it can target the overexpression of certain cancer cells and act precisely to inhibit tumor growth.
Second, this compound is also involved in the exploration of drugs for neurological diseases. Neurological diseases such as Alzheimer's disease, Parkinson's disease, etc., seriously affect the quality of life of patients. Studies have found that such compounds may regulate neurotransmitter levels, inhibit neuroinflammation, play a protective role in the nervous system, and provide direction for the development of related therapeutic drugs.
Third, it has also emerged in the development of immunomodulatory drugs. Immune system disorders can cause a variety of diseases, such as autoimmune diseases. The compound may regulate the function of immune cells and restore the balance of the immune system, which has potential value in the treatment of autoimmune diseases.
In conclusion, N - (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide has broad prospects in the field of medicine and is expected to make significant contributions to human health.
What is the synthesis method of N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indol-6-yl) pyridine-4-carboxamide
The synthesis of N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide is in the field of organic synthetic chemistry and requires a multi-step reaction to achieve it.
The choice of starting materials is very critical. Benzo [cd] indole derivatives and pyridine-4-carboxylic acid derivatives are often used as bases. The first step may require specific modification of benzo [cd] indole to introduce the structure of 1-ethyl-2-oxo. This may be achieved by alkylation to add ethyl, followed by oxidation to carbonyl, so that it has a 2-oxo state.
Pyridine-4-carboxylic acid derivatives also need to be pretreated. Or activated, such as converted into active acid chloride or acid anhydride form, so that subsequent amidation reaction with the modified benzo [cd] indole derivatives occurs.
In the amidation reaction step, the reaction conditions need to be selected appropriately. Choose a mild base to neutralize the acid generated by the reaction to promote the positive progress of the reaction. Commonly used bases such as triethylamine, pyridine, etc. Reaction solvents also need to be considered. Halogenated hydrocarbons and aromatic hydrocarbon solvents are also good choices because they can dissolve the reactants well and are compatible with the reaction system.
During the reaction process, appropriate monitoring means need to be used to control. Such as thin-layer chromatography (TLC), the reaction progress can be observed in a timely manner to help determine the end point of the reaction. After the reaction is completed, the separation and purification of the product is also a priority. Column chromatography can be used to obtain purified N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide products.
What is the safety of N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indol-6-yl) pyridine-4-carboxamide
In order to discuss the safety of N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide, it needs to be carefully studied.
This compound, in the field of chemistry, has a unique structure, 1-ethyl, 2-oxo and other groups are connected, and the structure is complex. However, its safety, the first consideration should be toxicity. Many previous studies have focused on the interaction between compound molecules and various substances in living organisms. If this substance enters the organism, or interacts with key components such as proteins and nucleic acids. If it binds to proteins, or causes protein conformational changes, which in turn affect protein functions, such as enzyme activity, or disrupt metabolic pathways.
Then talk about its mutagenicity. The genetic material of organisms, that is, nucleic acids, if affected by this compound, may cause mutations or deletions of base pairs. Once the genetic material is altered, or the abnormal proliferation of cells is caused, or even cancerous.
And consider its environmental safety. If this compound flows into the environment, in soil, water, or through chemical and biological transformation, new substances are generated. It affects the ecological balance in the soil microbial community, or affects aquatic organisms, from plankton to fish, the food chain may be destroyed.
However, today, although there is no conclusive and complete study to determine its safety. However, based on chemical principles and past experience with similar compounds, caution should be taken. Experimental research needs to be done step by step to explore the detailed information of its metabolism and toxicology in organisms, and also to consider its fate and effects in the environment. In this way, the certainty of its safety can be obtained, which can be used or prevented in the future.
What is the market outlook for N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indol-6-yl) pyridine-4-carboxamide?
N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide, which has considerable market prospects at present.
Looking at the field of pharmaceutical research and development today, many studies have focused on the exploration of novel compounds to find those with unique pharmacological activities. This compound has a unique structure and may have potential biological activity and medicinal value. In the development of anti-tumor drugs, many compounds with similar structures have shown the ability to inhibit the proliferation of tumor cells. N- (1-ethyl-2-oxo-1,2-dihydrobenzo [cd] indole-6-yl) pyridine-4-formamide may also have similar effects. If further research and development are carried out, it may add a new army to the anti-tumor drugs and occupy a place in the market.
Furthermore, the research and development of drugs for neurological diseases is also a hot spot. Such structural compounds may have effects on relevant targets of the nervous system. If it can be confirmed that they have an improvement or therapeutic effect on neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, the market prospect will be extremely promising. Due to the limited availability of effective drugs for such diseases, the advent of new drugs will surely attract much attention and provoke a strong response from the market.
However, if it wants to succeed in the market, it also faces challenges. Drug research and development requires many rigorous tests. From basic research to clinical trials, each step requires a lot of manpower, material resources and time. And the market competition is fierce, and there are many potential drugs of the same type. Only by virtue of excellent R & D efficiency, reliable drug efficacy and safety can it stand out and paint a brilliant chapter in the picture of the market prospect.