methyl pyrazolo[1,5-a]pyridine-3-carboxylate

Methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters are useful in many fields. In the field of medicinal chemistry, it is often a key intermediate in the synthesis of active pharmaceutical ingredients. Due to the unique structure of pyrazolopyridine, compounds are endowed with various biological activities, such as anti-inflammatory, antibacterial, and anti-tumor. By modifying this structure, chemists can create new drugs with strong targeting and good efficacy.
In the field of materials science, it may involve the preparation of organic optoelectronic materials. Because its structure has specific electronic properties, it may be used to prepare Light Emitting Diodes, solar cells and other devices, which can help improve the photoelectric properties of materials and make the device performance better.
In the field of pesticide research and development, methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters also have potential value. It may be structurally modified to create new pesticides that are highly effective in killing pests and environmentally friendly, helping agricultural pest control and ensuring crop harvests.
In addition, in organic synthetic chemistry, it is often used as a basic building block for building complex organic molecules. Chemists can functionalize it through various organic reactions, expand its structural complexity, and provide the possibility for the synthesis of more novel organic compounds, promoting the development of the field of organic chemistry.

Methylpyrazolo [1,5-a] pyridine-3-carboxylate, this is an organic compound. Its physical properties are unique, let me explain in detail.
Looking at its appearance, under room temperature and pressure, it is mostly in the state of white to light yellow crystalline powder, just like the fine snow that falls at the beginning of winter, delicate and pure. The powder is uniform in texture, without obvious agglomeration, and feels soft to the touch.
When it comes to melting point, it is in a specific temperature range. This temperature is the key node for its transformation from solid to liquid state, just like the opportunity for matter to metamorphose. At this temperature limit, the balance of forces between molecules is broken, the lattice structure gradually disintegrates, and the solid state gradually melts into a flowing liquid. The specific values vary depending on the purity of the compound and the determination conditions, but the approximate range is relatively stable, providing an important reference for related research and applications.
Solubility is also one of its important physical properties. In organic solvents, such as ethanol, dichloromethane, etc., it exhibits different degrees of solubility. In ethanol, it is quite soluble, just like fish entering water, the molecules are uniformly dispersed to form a clear and transparent solution. In water, the solubility is relatively poor, because its molecular structure contains hydrophobic groups, and the interaction with water molecules is weak, so it is difficult to dissolve in large quantities.
In addition, the compound has a certain volatility. Although the volatilization rate is slow at room temperature, the volatilization intensifies under heating or specific conditions. This property affects its storage and use environment and needs to be properly controlled. Its density also has a specific value. Although it is not a daily focus, density data is of great significance to the measurement of substances and the design of reaction systems in precise chemical experiments and industrial production.
The physical properties of methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters are of great value in organic synthesis, drug development and other fields, laying the foundation for researchers to further study and rationally apply this compound.

The chemical synthesis of methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters requires delicate steps and suitable reagents.
The first step is often to use suitable pyridine derivatives as starting materials. Under suitable reaction conditions, such as in a specific solvent, a specific base and halogenated reagent are added, and a halogenation reaction is carried out to introduce a halogen atom at a specific position on the pyridine ring. This halogenation reaction requires fine regulation of temperature, time and reagent dosage to prevent the growth of side reactions.
In the second step, the halogen-containing pyridine derivatives are condensed with pyrazoles. This process often requires the help of a catalyst to react in a specific temperature range. The choice of catalyst is very important, which can effectively improve the reaction rate and selectivity. During the reaction, the properties of the solvent also have a great influence on the reaction process. It is necessary to choose a solvent suitable for the reactants and catalysts to ensure the smooth progress of the reaction.
Furthermore, the condensation product needs to be esterified to obtain the target product methylpyrazolo [1,5-a] pyridine-3-carboxylic acid ester. The esterification reaction is usually carried out with alcohols (such as methanol) and carboxyl-containing precursors under acid catalysis or other suitable conditions. The strength and dosage of acid catalysts need to be strictly controlled, and the temperature needs to be precisely controlled to complete the esterification reaction efficiently and reduce unnecessary side reactions.
The whole synthesis process requires careful separation and purification of each step of the product, such as column chromatography, recrystallization and other methods to ensure the purity of the product, providing high-quality raw materials for the next reaction, and finally obtaining high-purity methylpyrazolo [1,5-a] pyridine-3-carboxylate.

It is difficult to determine the price range of methylpyrazolo [1,5-a] pyridine-3-carboxylate in the market. The price depends on many factors, such as the source of the material, the difficulty of preparation, the situation of supply and demand, and the quality.
If the material is easy to harvest, convenient to prepare, and oversupply, its price may be relatively low; conversely, if the material is rare, complicated to prepare, and the demand is too high, the price will be high.
In the place where chemical raw materials are traded, the price of this compound may fluctuate due to differences in quality. For high quality, the price may reach tens of gold per gram, and for low quality, the number of gold per gram is unknown.
However, if you want to determine the exact price range, you need to study the current market conditions in detail. You can consult the chemical raw material supplier, or check the relevant information on the chemical trading platform to get a more accurate price range.

Methylpyrazolo [1,5-a] pyridine-3-carboxylic acid ester, the manufacturer of this product is quite numerous in the world. This test is for Jun Chen and one or two.
First of all, there is Sigma-Aldrich, which is a leader in the chemical reagent industry and is well-known. Its various fine chemicals, including methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters, are of high quality and are trusted by many scientific research institutions and enterprises. Its production process is exquisite, and the quality control is extremely strict. The products produced are often used for scientific research and high-end production.
Looking at China, Shanghai search banner biochemical technology joint stock company also has strengths. Its company specializes in the research and development and production of scientific research reagents, and its product line is rich and diverse. Its methylpyrazolo [1,5-a] pyridine-3-carboxylate products are not only popular in the domestic market, but also exported overseas, known for their high cost performance and stable supply. Many domestic scientific research institutions and enterprises often rely on the raw materials they provide for various experiments and production.
There is also Tixi Ai (Shanghai) Chemical Industry Development Co., Ltd., which is a TCI enterprise in China. TCI has a long-standing reputation in the global chemical reagent industry. Tixi Ai (Shanghai) inherits its technology and concept, and produces methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters, which are famous for their high quality and high purity, and can meet the strict needs of different customers.
These are all common manufacturers, but the market is vast, and there must be many manufacturers also engaged in the production of this product, each with its own characteristics and advantages. If you need it, you can explore it in detail to find the most suitable choice.