Methyl cinnamyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate

This is an organic compound named methyl cinnamyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydro-3,5-pyridinedicarboxylate. To know its chemical structure, it is necessary to analyze the information contained in the nomenclature.
"Pyridinedicarboxylate" shows that its core structure is a pyridine ring, and it is connected with a dicarboxylate group at the 3,5 position. "1,4-dihydro" indicates that the 1,4 position of the pyridine ring is in the dihydro form and has two less double bonds than the pyridine ring. "2,6-dimethyl" indicates that there is a methyl substitution at the 2,6 position of the pyridine ring. " 4- (3-nitrophenyl) "means that the 4-position of the pyridine ring is connected to a 3-nitrophenyl group, that is, the 3-position of the benzene ring has a nitro group." Methyl cinnamyl "means that an ester-oxygen group of the dicarboxylate is methyl cinnamyl, and the cinnamyl group is a phenylpropenyl group structure. This methyl group or is attached to a certain carbon of the cinnamyl group.
In summary, the chemical structure of this compound is based on 1,4-dihydro-3,5-pyridinedicarboxylate as the core, with methyl group at 2,6 positions, 3-nitrophenyl at 4 positions, and an ester group is methyl cinnamyl ester. Its structure is complex, composed of a clever combination of pyridine ring, phenyl ring and various substituents.

This chemical substance is called methyl cinnamyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydro-3,5-pyridinedicarboxylate. Its main uses are as follows:
First, in the field of medical chemistry, it is often used as a key intermediate. After ingenious chemical reaction modification, it can construct drug-active molecules with more complex structures. Because the substance contains specific structures such as pyridine rings and nitrophenyl groups, these structures endow it with unique physicochemical and biological activities, which can interact with biological targets in the body in a specific way. Therefore, scientists have used this to explore the development of drugs with novel mechanisms of action, such as anti-tumor drugs, by precisely designing molecular structures to target specific proteins or signaling pathways of cancer cells, in order to achieve the purpose of efficient anti-cancer; or for the development of cardiovascular drugs, by means of their interaction with receptors or enzymes related to the cardiovascular system, regulate physiological functions and achieve the efficacy of treating cardiovascular diseases.
Second, in the field of materials science, it can be used to prepare functional polymer materials. Introducing it into polymer systems can significantly improve the optical, electrical and thermal properties of materials. For example, synthesizing materials with special optical responses, under different lighting conditions, exhibit unique photochromic or fluorescent properties, which can be applied in optical storage, sensors and other fields. Because the specific groups in its structure can absorb or emit light of a specific wavelength, the optical properties of the material can be precisely regulated. Furthermore, by adjusting its content and distribution in polymer materials, the electrical properties of the material can also be optimized, such as improving the conductivity or dielectric properties of the material, providing a new material choice for the development of electronic devices.

To prepare methyl cinnamyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydro-3,5-pyridyl dicarboxylate, the method is as follows:
First take an appropriate amount of 3-nitrobenzaldehyde, 2,6-dimethyl-4-piperidone and dimethyl malonate and place them in a clean reaction vessel. Add an appropriate amount of catalyst, such as hexahydropyridine, this catalyst can promote the reaction and increase its rate. < Br >
Then, the reaction system is placed in a moderate temperature environment, heated in an oil or water bath, and the temperature is maintained in a certain range, between about 80 and 100 degrees Celsius, so that the reactants can be fully contacted and reacted. During the reaction, it is necessary to continuously stir to make the system uniform and ensure a smooth reaction.
After several hours of reaction, the reaction of the system reaches the expected level, and after a little cooling, the product is separated and purified. It can be extracted with an organic solvent, such as ethyl acetate, etc., to enrich the product in the organic phase. Then through column chromatography and other means, fine separation, removal of impurities, to obtain pure methyl cinnamyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydro-3,5-pyridinedicarboxylate.
The whole process needs to pay attention to the control of temperature, catalyst dosage and reaction time to ensure the purity and yield of the product.

Methyl cinnamyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydro-3,5-pyridinedicarboxylate, which is an organic compound. Its physical and chemical properties are worth exploring.
Looking at its physical properties, it is usually in a solid state at room temperature and pressure. Due to the existence of various forces between molecules, it is so aggregated. Its melting point also has characteristics. The melting point depends on the regularity and interaction strength of the molecule. The molecular structure of this compound has a certain complexity, so the melting point may be in a specific range. The boiling point is related to the intermolecular force and vapor pressure. Due to the presence of various groups in the molecule, the intermolecular force is complex and the boiling point may be higher.
On its chemical properties, this compound contains a pyridine ring. The pyridine ring has certain aromaticity and can participate in a variety of aromatic electrophilic substitution reactions. The methyl group attached to the ring, because the methyl group is the power supply group, or changes the electron cloud density of the pyridine ring, affects the reaction activity. There are also nitrophenyl groups. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and also affect the reaction activity of the whole molecule. At the same time, the ester group can undergo hydrolysis reaction, and the hydrolysis rate is different from the product under acidic or basic conditions. Hydrolysis under alkaline conditions is easier to proceed, and corresponding carboxylate and alcohol can be obtained. The carbon-carbon double bond in the molecule can participate in the addition reaction, such as addition with halogens, hydrogen halides, etc., to expand its chemical transformation path.

Nowadays, the name of the compound is "Methyl + cinnamyl + 2,6 - dimethyl - 4 - (3 - nitrophenyl) -1,4 - dihydro - 3,5 - pyridinedicarboxylate", and its market prospects are worth exploring.
This compound may have potential in the field. The way to do this is to seek the efficacy and safety of the product. If this compound is studied in depth, it can be used for specific diseases, such as certain inflammation or chronic diseases. If it is effective, and the side effects are serious, it will definitely attract the attention of enterprises and get a share of the market.
Furthermore, the field of chemical synthesis or its stage. The beauty of chemical synthesis lies in the ability to create new products. If the synthesis method of this compound can be perfected and the cost can be controlled, it will be easy to quantity. For chemical enterprises, quantity means modular efficiency, and more products can be put into the market, thus making profits. Moreover, its particularity may provide new ideas for the synthesis of other compounds, leading to the tide of research and expanding the field of chemical synthesis.
However, it also faces many challenges. During the research period, a lot of manpower and material resources need to be invested to clarify its properties, efficacy and safety. And the market is intense. If other similar compounds have been developed first, it will not be small if they want to highlight the importance. However, if they can be well researched and used, this compound will not be able to make a difference in the market.