Methyl 6 Oxo 1h Pyridine 3 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

methyl 6-oxo-1H-pyridine-3-carboxylate

    Specifications

    HS Code

    513268

    Chemical Formula C7H7NO3
    Molar Mass 153.14 g/mol
    Appearance Solid (usually white or off - white)
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Melting Point Typically in a certain range (needs specific experimental data)
    Boiling Point Requires experimental determination
    Density Needs experimental measurement
    Flash Point Requires experimental determination
    Pka Related to the acidic nature of the pyridine - carboxylate group, needs experimental data

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    Frequently Asked Questions

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    What is the chemical structure of methyl 6-oxo-1H-pyridine-3-carboxylate?
    Methyl-6-oxo-1H-pyridine-3-carboxylic acid ester, this is one of the organic compounds. Looking at its name, its structural characteristics can be deduced. "Methyl" refers to a group containing one carbon atom and three hydrogen atoms, expressed as "-CH", and is often used as a substituent in organic structures. "6-oxo" indicates that there is an oxygen atom connected by a double bond at the 6th position of the pyridine ring. The presence of this carbonyl group significantly affects the chemical properties of the compound, such as nucleophilic addition reaction activity. " 1H-pyridine "indicates that the compound has a basic structure of a pyridine ring. The pyridine ring is aromatic and consists of five carbon atoms and one nitrogen atom to form a six-membered ring structure. 1H refers to the hydrogen atom at the 1st position of the pyridine ring." 3-carboxylate "indicates that the 3rd position of the pyridine ring is connected with a carboxylic acid ester group, namely -COOCH, which imparts specific chemical activities and physical properties to the compound, such as hydrolysis properties. In summary, the chemical structure of methyl-6-oxo-1H-pyridine-3-carboxylic acid esters is an organic compound with methyl, carbonyl and carboxylic acid ester groups attached to specific positions on the pyridine ring.
    What are the main uses of methyl 6-oxo-1H-pyridine-3-carboxylate?
    Methyl-6-oxo-1H-pyridine-3-carboxylic acid ester, which has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help create a variety of drugs for the treatment of diseases. Due to its special structure, it can be cleverly combined with many bioactive molecules. After chemical modification and transformation, compounds with specific pharmacological activities can be obtained, or used to fight inflammation, or for cardiovascular diseases, neurological diseases, etc., which are expected to play an effect.
    In the field of pesticides, it also has important applications. With its unique chemical properties, pesticide ingredients with high targeting and high efficiency for pests can be derived. It can interfere with the physiological and metabolic processes of pests, or damage their nervous system, respiratory system and other key physiological functions, so as to achieve effective prevention and control of crop pests, ensure the robust growth of crops, and improve food yield and quality.
    In the field of organic synthetic chemistry, it is an extremely important basic raw material. Chemists can use various chemical reactions as a starting point to build organic compounds with more complex and diverse structures. By introducing different functional groups, changing the molecular spatial configuration, expanding the variety of organic compounds, laying the foundation for the research and development of new materials and the preparation of fine chemicals. Methyl-6-oxo-1H-pyridine-3-carboxylate may play an indispensable role in the preparation of fine chemicals such as high-performance plastic additives and special functional coatings.
    What are the synthesis methods of methyl 6-oxo-1H-pyridine-3-carboxylate
    There are many ways to synthesize methyl 6-oxo-1H-pyridine-3-carboxylic acid esters throughout the ages.
    One of them can be started from the corresponding pyridine derivatives. First, find a pyridine containing an appropriate substituent, and use it as a base to chemically transform the group at a specific position on the pyridine ring into a 6-oxo structure under specific conditions. For example, select a suitable pyridine halide, react with a nucleophilic reagent under the action of a base and a specific catalyst, introduce a carbonyl group, and then adjust the reaction conditions to promote carbonyl based on 6-position localization, followed by esterification reaction, with alcohol and carboxyl-containing intermediates, with the assistance of acid catalysis or condensation agent, to generate the target methyl 6-oxo-1H-pyridine-3-carboxylic acid ester.
    Second, the strategy of constructing a pyridine ring can also be used. Using small molecules containing nitrogen and carbonyl as raw materials, pyridine rings are built through multi-step reactions. For example, using a β-dicarbonyl compound with ammonia or amine, at a dehydrating agent and at a suitable temperature, the prototype of the pyridine ring is first formed, and then the groups on the ring are modified to introduce oxygen atoms at the 6 position to form a 6-oxo structure. Finally, esterification is performed to obtain the desired product.
    Furthermore, the method of transition metal catalysis can also be used. With appropriate halogenated aromatics and ligands containing nitrogen and carbonyl groups, under the catalysis of transition metals such as palladium and copper, through multi-step coupling reactions, pyridine rings are constructed and 6-oxo structures are formed at the same time. After subsequent esterification steps, methyl 6-oxo-1H-pyridine-3-carboxylic acid esters are obtained.
    All synthesis methods have their own advantages and disadvantages, and they need to be carefully selected according to factors such as the availability of raw materials, the ease of control of reaction conditions, and the purity requirements of target products.
    What are the physical properties of methyl 6-oxo-1H-pyridine-3-carboxylate?
    Methyl-6-oxo-1H-pyridine-3-carboxylate, this is an organic compound. Its physical properties are particularly important and are related to many chemical applications.
    Looking at its appearance, it often takes a white to light yellow crystalline powder shape, which is easy to observe and initially distinguish. Its melting point is about a specific temperature range, which can help to accurately identify and determine the purity. In organic solvents, such as ethanol and acetone, it exhibits some solubility, but in water, the solubility is relatively limited. This difference in solubility is due to its molecular structure characteristics, and the functional groups contained in it interact differently with the solvent molecules.
    Furthermore, the density of this substance is moderate, although not extremely light or extremely heavy. Its density value is crucial for the measurement and mixing ratio control of materials in chemical processes. In addition, its stability cannot be ignored. Under conventional environmental conditions, it can remain relatively stable. In case of extreme conditions such as high temperature, strong acid and alkali, or chemical reactions occur, resulting in structural changes.
    Its physical properties are of great significance in chemical synthesis, drug development and other fields. During synthesis, the reaction conditions can be optimized according to solubility and melting point, and the yield and purity can be improved. In drug development, stability and solubility are related to drug preparation, absorption and efficacy. Therefore, knowing the physical properties of methyl-6-oxo-1H-pyridine-3-carboxylate is a basic task for scientific research and industrial applications.
    What is the market outlook for methyl 6-oxo-1H-pyridine-3-carboxylate?
    The market prospect of methyl-6-oxo-1H-pyridine-3-carboxylate is of great concern to many people. It has a unique position in the field of organic synthesis.
    From the perspective of pharmaceutical chemistry, such compounds may be the key intermediates for the creation of new drugs. At present, pharmaceutical research and development is booming, and the demand for novel and highly active compounds is increasing. Methyl-6-oxo-1H-pyridine-3-carboxylate, because of its specific chemical structure, may provide different ideas for the design of drug molecules, and may have potential uses in the research and development of anti-cancer, anti-infection and other diseases. This is one of the great opportunities for its market prospects.
    As for the field of materials science, with the progress of science and technology, the exploration of functional materials has not been endless. The special structure of this compound may endow materials with unique optical and electrical properties. If it can be developed in this field, such as the preparation of new optoelectronic materials, its market potential should not be underestimated.
    However, its market prospects are not completely smooth. The complexity of the synthesis process and the difficulty of obtaining raw materials are all factors that affect its large-scale production and application. If there is a breakthrough in the synthesis method, the process can be simplified, the cost can be reduced, and the stability of the supply of raw materials can be ensured, so that it can stand out in the market competition and win a broader prospect.