methyl 6-cyanopyridine-3-carboxylate

Methyl-6-cyanopyridine-3-carboxylic acid ester, which has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to create a variety of drugs. The structural properties of Gainpyridine and cyano and ester groups endow molecules with specific chemical and pharmacological activities, whereby other functional groups can be introduced through organic synthesis reactions to build complex molecular structures with biological activities. For example, for the treatment of specific diseases, the modification of this intermediate may enhance the efficacy of drugs and reduce side effects.
In the field of materials science, it may involve the preparation of organic optoelectronic materials. The conjugated structure of the pyridine ring gives the compound unique optical and electrical properties, or it can be used to synthesize Light Emitting Diode (OLED) materials, organic solar cell materials, etc. Using it as a starting material, the molecular structure and electron cloud distribution can be adjusted by chemical synthesis, and key performance indicators such as material photoelectric conversion efficiency and stability can be optimized.
Furthermore, in the field of pesticide chemistry, it also has its own figures. It can be used as an important raw material for the synthesis of new pesticides. Using its structural characteristics, it can create pesticide products with high selectivity, high efficiency and low toxicity to pests. Modifying its cyano and ester groups may improve the degradation characteristics and biological activity of pesticides in the environment, and help the sustainable development of agriculture.
In summary, methyl-6-cyanopyridine-3-carboxylate plays an important role in many fields such as medicine, materials, and pesticides due to its unique structure, providing a key chemical raw material foundation for the development of related fields.

The synthesis method of fuchmethyl-6-cyanopyridine-3-carboxylic acid ester has been investigated by many scholars in the past, and the following is a brief number of methods.
First, 6-bromopyridine-3-carboxylic acid methyl ester is used as the starting material, and cuprous cyanide is synthesized in a suitable organic solvent at a specific temperature and with the assistance of a catalyst. Among them, organic solvents such as N, N-dimethylformamide (DMF) can create a good reaction environment, so that the reactants can be fully dissolved and contacted to promote the reaction. The choice of catalysts is crucial, such as 1,10-phenanthroline, which can effectively reduce the activation energy of the reaction and improve the reaction rate and yield. When reacting, close attention should be paid to the control of temperature, usually at 100-150 ° C. Too high or too low may affect the reaction effect.
Second, using 6-aminopyridine-3-carboxylic acid methyl ester as raw material, it is converted into diazonium salt by diazotization reaction, and then interacts with cyanide reagents such as cuprous cyanide or potassium cyanide to achieve the introduction of cyanide. The diazotization reaction needs to be carried out in a low temperature environment, usually at 0-5 ° C, to prevent the decomposition of diazonium salts. Sodium nitrite and hydrochloric acid are commonly used in diazotization reagents, and the two react to form nitrous acid, which then reacts with amino groups to form diazonium salts. Subsequently, it is necessary to pay attention to the regulation of the reaction conditions in this step to ensure the smooth completion of the reaction and obtain the target product with higher yield.
Third, pyridine-3,6-dicarboxylic acid is used as the starting material, and pyridine-3,6-dicarboxylate is first esterified to obtain dimethyl pyridine-3,6-dicarboxylate, and then a cyanyl group is selectively introduced at an appropriate position. The esterification reaction usually uses strong acids such as sulfuric acid as the catalyst and is heated and refluxed in an alcohol solvent. For the introduction of cyanyl groups, the target position can be halogenated first by halogenation reaction In this process, the selectivity and condition control of each step of the reaction are extremely important, which are related to the purity and yield of the final product.

Methyl 6-cyanopyridine-3-carboxylic acid ester is an important compound in the field of organic chemistry. It has many unique physical properties and has attracted much attention in chemical research and industrial production.
Looking at its properties, at room temperature, this substance is mostly in the state of white to light yellow crystalline powder, which is stable and easy to store and transport. Its melting point range is about [specific melting point value], which is of great significance for its separation, purification and identification. When heated to the melting point, the compound gradually melts from solid to liquid. This transformation process requires precise temperature control to ensure the purity and chemical properties of the substance.
In terms of solubility, methyl 6-cyanopyridine-3-carboxylate exhibits good solubility in common organic solvents such as ethanol and acetone. This property allows it to be uniformly mixed with a variety of reactants in organic synthesis reactions, effectively promoting the reaction. In water, its solubility is relatively limited, and this difference can be exploited in extraction, separation, etc., to achieve purification and separation of compounds by means of different solvent solubility.
In addition, the density of the compound is about [specific density value], which is a physical constant that helps to operate accurately in links such as solution preparation and reaction material measurement. Stable density allows experimenters to accurately convert mass according to volume, providing reliable data support for chemical experiments and industrial production, ensuring that reactions occur according to predetermined stoichiometric ratios, and improving product quality and yield.

The market price of methyl-6-cyanopyridine-3-carboxylate is difficult to determine. This is because the market price often changes for a variety of reasons, and cannot be generalized.
First, the supply and demand of materials has a great impact on its price. If the demand for this product is strong and the output is not sufficient, the price will rise; conversely, if the supply exceeds the demand, the price may decline. And in different seasons, demand may fluctuate, and the price will fluctuate.
Second, the preparation cost also affects the price. The cost of raw materials, the simplicity of the production process, and the energy consumption required for production are all cost components. If the raw materials are rare or the process is complex, the cost will increase, and the selling price will also increase.
Third, the market competition situation also affects the price. If there are many products and sales of this product in the market, the competition is fierce, and it is for share, or the price is reduced for promotion; if only a few companies operate, they have the potential to monopolize, and the price may be high.
Fourth, the macroeconomic environment, policies and regulations also play a role. The economic situation is good, the market is active, and the price may be supported; policies encourage or restrict production and sales, and also make the price change.
In the past, in the chemical raw material trading market, the price of such fine chemicals was different. According to past transaction records, the price may be between tens of yuan and hundreds of yuan per kilogram, but this is only an approximate number, not the current exact price. To know the current market price, it is advisable to consult chemical product suppliers, traders, or professional chemical product information platforms to obtain near-real-time price information.

Methyl-6-cyanopyridine-3-carboxylic acid ester is a kind of organic compound. When storing and transporting, many matters need careful attention.
First words storage. This compound may be active in nature, so it should be placed in a cool, dry and well-ventilated place. The cover is sensitive to temperature and humidity, and the high temperature and humid environment can easily cause chemical reactions and damage its quality. And it should be stored separately from oxidizing agents, acids, alkalis and other substances. Because of contact with it, or cause severe reactions, it will cause safety hazards. Furthermore, the storage place should be equipped with suitable materials to contain leaks to prevent accidental leakage and can be properly handled in a timely manner.
As for transportation, there are also many key points. Before transportation, it is necessary to ensure that the packaging is complete and well sealed to prevent leakage during transportation. During transportation, the temperature and humidity should be strictly controlled, and appropriate temperature control and moisture-proof equipment can be used. The transportation vehicle should also be clean and dry, and no substances that may react with it should be left behind. And the transportation personnel should be familiar with the characteristics of this compound and emergency treatment methods, and in case of emergencies, they can respond quickly and correctly. When handling, it is necessary to pack and unload lightly to avoid collision and friction, so as to prevent package damage and lead to leakage accidents. In this way, the safety and quality of methyl-6-cyanopyridine-3-carboxylic acid esters can be ensured when storing and transporting them.