Methyl 6 Chloro 2 Pyridinecarboxylate
pyridine pyrrole pyrazine piperidine piperazine

Methyl 6-chloro-2-pyridinecarboxylate

    Specifications

    HS Code

    890172

    Chemical Formula C7H6ClNO2
    Molar Mass 171.58 g/mol
    Appearance Colorless to light yellow liquid or solid
    Boiling Point Around 230 - 235 °C
    Melting Point 19 - 21 °C
    Density 1.285 g/cm³ (approx.)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, acetone
    Flash Point 102 °C
    Purity Typically high - purity commercial products around 98%+

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    General Information
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    Frequently Asked Questions

    As a leading Methyl 6-chloro-2-pyridinecarboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is Methyl 6-chloro-2-pyridinecarboxylate?
    Methyl 6-chloro-2-pyridinecarboxylate has a wide range of uses. In the field of medicine, it is often a key intermediate and helps to synthesize a variety of drugs. The structure of Gainpyridine has unique activity and stability in many drug molecules. The specific functional group of 6-chloro-2-pyridinecarboxylate can be combined with other groups through various chemical reactions to construct drugs with complex structures and specific functions.
    In the field of pesticide creation, it also has important uses. It can be used to prepare pesticides, fungicides and other pesticide products. With its special chemical structure, it can interfere with the physiological process of harmful organisms, inhibit their key enzyme activities, or destroy their cell structure, so as to achieve the purpose of preventing and controlling harmful organisms.
    Furthermore, in the field of materials science, methyl 6-chloro-2-pyridinecarboxylate may be used as a raw material for synthesizing functional materials. The polymers or composites it participates in the reaction may have unique electrical, optical or mechanical properties, providing possibilities for material innovation.
    Therefore, methyl 6-chloro-2-pyridinecarboxylate plays an important role in medicine, pesticides, materials and other fields, promoting the development and progress of various fields.
    What are the synthetic methods of Methyl 6-chloro-2-pyridinecarboxylate?
    There are many different methods for making methyl 6-chloro-2-pyridinecarboxylate. One method is to use 6-chloro-2-pyridinecarboxylic acid and methanol as raw materials, add a catalyst at a suitable temperature and pressure, and carry out the esterification reaction. The catalyst used is either sulfuric acid, p-toluenesulfonic acid and other protonic acids, or strong acidic ion exchange resins. When reacting, pay attention to the control of temperature, do not make it too high, avoid side reactions, and affect the purity and yield of the product.
    There are also 2-chloro-6-methylpyridine as the starting material. First, it reacts with a suitable oxidant to oxidize methyl to a carboxyl group to obtain 6-chloro-2-pyridinecarboxylic acid. Then, according to the above esterification method, it interacts with methanol to form methyl 6-chloro-2-pyridinecarboxylate. In this oxidation step, the choice of oxidant is very important, such as potassium permanganate, potassium dichromate and other inorganic oxidants, or peroxy acid organic oxidants, each has its own advantages and disadvantages, and must be selected according to the actual situation.
    There are also pyridine derivatives prepared by multi-step reaction. For example, a suitable substituent is introduced to the pyridine ring first to build the desired structure, and then carboxylation, esterification and other reactions are carried out. Although there are many steps in this way, the molecular structure can be precisely modified according to specific needs to obtain the target product. Each step of the reaction requires attention to the optimization of the reaction conditions. The proportion of reactants, reaction time, temperature and other factors are all related to the quality and quantity of the product.
    What are the physical properties of Methyl 6-chloro-2-pyridinecarboxylate?
    Methyl 6 - chloro - 2 - pyridinecarboxylate is an organic compound, and its physical properties are quite characteristic. This compound is usually in a solid state, and its appearance may be a white to light yellow crystalline powder. Its melting point is in a specific range, about [X] ° C, and this melting point characteristic is crucial for the identification and purification of this substance.
    In addition, its boiling point also has a corresponding value, about [X] ° C. The boiling point reflects the temperature conditions at which the compound changes from liquid to gas when heated, which is of great significance for its separation and purification operations in chemical processes.
    In terms of solubility, Methyl 6-chloro-2-pyridinecarboxylate exhibits a certain solubility in organic solvents such as ethanol and acetone, but is difficult to dissolve in water. This difference in solubility plays an important role in experimental operations such as extraction, recrystallization, and product separation in industrial production.
    Its density is also an important physical parameter, about [X] g/cm ³. Density data are indispensable in material balance and hydrodynamic calculations involving the compound.
    In addition, the compound has a specific odor. Although the description of the odor is difficult to accurately quantify, it also provides an intuitive basis for identifying the substance.
    In practical applications and research, these physical properties are interrelated and influenced, and need to be fully considered to achieve effective manipulation and utilization of Methyl 6-chloro-2-pyridinecarboxylate.
    What are the chemical properties of Methyl 6-chloro-2-pyridinecarboxylate?
    Methyl 6-chloro-2-pyridine carboxylic acid ester, this is an organic compound with specific chemical properties. Its appearance is often white to light yellow crystalline powder, which has certain stability. When it encounters hot topics, open flames or strong oxidants, it is afraid of chemical reactions and even causes danger.
    Its solubility is quite important. It has good solubility in organic solvents such as ethanol, acetone, dichloromethane, etc. This property is of great significance in organic synthesis and is convenient for it to participate in various reactions. Due to its structure containing chlorine atoms and pyridine rings, its chemical activity is unique. Chlorine atoms can be replaced by other functional groups through nucleophilic substitution reactions, so that a series of derivatives can be synthesized. The pyridine ring gives it alkalinity and can react with acids to form salts. This property is widely used in medicinal chemistry, materials science and other fields.
    In addition, methyl 6-chloro-2-pyridyl carboxylate can be used as an intermediate in the synthesis of medicine and pesticides. In the field of medicine, after further reaction modification, it is expected to form drug molecules with specific biological activities; in the field of pesticides, it can be used to create new and efficient pesticides to control pests and diseases.
    In terms of storage, it needs to be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent moisture and deterioration, and to ensure that its chemical properties are stable for subsequent use.
    What is the price of Methyl 6-chloro-2-pyridinecarboxylate in the market?
    I have not obtained the exact price of methyl 6-chloro-2-pyridyl carboxylate on the market. The price of this compound often varies due to many reasons. First, purity is the key factor. If the purity is very high, it is suitable for fine chemical experiments or high-end pharmaceutical processes, and the price is high; if the purity is slightly lower, it is only for ordinary chemical synthesis, and the price is slightly lower.
    Second, the trend of supply and demand also affects its price. If the market demand for this product is strong and the supply is limited, the price will rise; if the supply exceeds the demand, the price may fall. Furthermore, the production method is also related to the cost. If complicated steps, expensive raw materials or special equipment are required to prepare, the price will also be high if the cost is high.
    In addition, the purchase quantity also affects the price. Bulk purchase, merchants may give discounts; small purchase, unit price or higher. And origin, transportation costs, etc., will make the price fluctuate. To know the exact price of this product, you need to consult the chemical raw material supplier, or check the relevant chemical product trading platform, in order to get the nearest accurate price.