METHYL 5-BROMO-2-HYDROXYPYRIDINE-3-CARBOXYLATE

The chemical properties of 5% iodine, 2% furacillin solution, and 3% boric acid ethanol are as follows:
###5% iodine
Iodine is an alcoholic solution of iodine. Iodine is a purple-black crystal with sublimation, which dissolves in alcohol to obtain this iodine.
In this iodine, iodine is the active ingredient. Iodine is chemically active and has strong oxidizing properties. It can react with many reducing substances, such as metal elements. It can oxidize metals and reduce itself. Take iron as an example, iodine reacts with iron to form ferrous iodide.
Alcohol, scientific name ethanol, is the solvent of iodine. Ethanol is flammable and can react violently with oxygen under ignition conditions to form carbon dioxide and water. And ethanol can react with active metals, such as sodium, to generate sodium ethanol and hydrogen.
Iodine interacts with ethanol in iodine and exists stably. However, when iodine encounters starch, it is a special blue color. This is a characteristic reaction of iodine. Because iodine molecules are embedded in the spiral structure of starch to form inclusion complexes, it is colored. This characteristic is often used to test starch.
###2% Furacillin Solution
Furacillin, an organic compound with nitrofuran structure. It is a yellow crystalline powder, slightly soluble in water, to obtain a 2% solution, often used for disinfection and preservative.
From the perspective of chemical properties, the nitro group in the molecule of furacillin has strong oxidation, which is the key to its disinfection and sterilization. Nitro can react with biological macromolecules such as bacterial proteins and nucleic acids, destroying their structure and function, causing bacterial death.
And furacillin has a certain acidity and alkalinity. Some groups in its structure can react with acid and alkali. Although its solution is neutral, its stability may change in different acid-base environments. In case of strong acid and alkali, it may cause molecular structure damage, which affects its disinfection effect.
In addition, furacillin has certain photosensitivity. Under long-term light exposure, photochemical reactions may occur, causing structural changes and reducing drug efficacy. Therefore, it often needs to be stored away from light.
###3% boric acid ethanol
Boric acid is a white powdery crystal or a scaly luster crystal on the triangular axis, with a slippery feel and no odor. It is soluble in water, alcohol, etc., to obtain a 3% boric acid ethanol solution.
Boric acid is weakly acidic and can be weakly ionized in water to produce hydrogen ions. Its acidity is due to the lack of electrons of boron atoms, which can accept lone pairs of electrons from oxygen atoms in water molecules, so that water releases hydrogen ions.
Ethanol is a solvent, and it has the properties of flammability and active metal reaction as described above. In 3% boric acid ethanol, boric acid and ethanol interact. Boric acid can change the polarity of ethanol solution and other physical properties, while ethanol affects the dispersion and dissolution of boric acid.
Boric acid ethanol solution can undergo neutralization reaction in case of alkali. The hydrogen ion in the boric acid and the hydroxide ion in the base combine to form water to form the corresponding borate salt. This solution is also often used in medical and other fields due to the disinfection and anti-corrosion properties of boric acid.

To prepare 5-hydroxy- 2-furanal and 3-ethyl pyridinecarboxylate, the following ancient methods can be used.
To make 5-hydroxy- 2-furanal, furfural is often used as the starting material. First take an appropriate amount of furfural, place it in a clean kettle, and add an appropriate amount of sodium hydroxide solution. The concentration of this liquid needs to be precisely prepared to ensure a smooth reaction. Control the temperature in a specific range, usually at a low temperature, such as 0 to 5 degrees Celsius, and stir slowly to fully blend the two. This reaction is a Connexaro reaction. Under the action of alkali, furfural dissimilates into furfuryl alcohol and sodium furoate. After the reaction is completed, the dilute acid is carefully neutralized and adjusted to a suitable pH value. At this time, sodium furoate is reformed into furfuric acid, but furfuryl alcohol does not react with it. Then, the organic phase is extracted with an organic solvent such as ether, and the organic phase is separated. The ether is removed by distillation to obtain furfuryl alcohol. Subsequently, the furfuryl alcohol is placed in another kettle, and a specific oxidant is added, such as a mixed system of manganese dioxide and sulfuric acid. The temperature is raised to a moderate temperature, about 60 to 80 degrees Celsius, to oxidize the furfuryl alcohol to 5-hydroxy- 2-furanal. After the reaction is completed, it is purified by distillation and recrystallization to obtain pure 5-hydroxy- 2-furanal.
As for the synthesis of ethyl 3-pyridinecarboxylate, niacin is the starting material. First take an appropriate amount of niacin, place it in a reactor, and add an excess of anhydrous ethanol. Ethanol is both a reactant and a solvent. Then add an appropriate amount of concentrated sulfuric acid, concentrated sulfuric acid as a catalyst, which can promote the reaction to accelerate. Heat and reflux at a temperature of about 78 to 80 degrees Celsius to esterify niacin and ethanol. During this process, keep stirring to make the reaction uniform. When the reaction lasts for a few days, when the reaction is almost complete and slightly cold, pour the reaction solution into ice water to neutralize the sulfuric acid and precipitate the crude 3-ethyl pyridinecarboxylate. The organic phase is extracted with an organic solvent such as dichloromethane, and then washed with saturated sodium bicarbonate solution and water to remove impurities. Then dried with anhydrous sodium sulfate, distilled to remove the solvent, and finally distilled under reduced pressure to obtain pure ethyl 3-pyridinecarboxylate.

5-Boron-2-furanylpyruvate and methyl 3-hydroxyacetate have their applications in many fields.
Boron is used in agriculture and can be used as a key trace element for plant growth. An appropriate amount of boron can help the development of plant reproductive organs, and it is very important for pollen germination and pollen tube elongation. Boron deficiency can easily cause plant flowers to be unreal. In the industrial field, boron compounds are often used in glass manufacturing to improve the heat resistance and chemical stability of glass. For example, borosilicate glass has excellent properties due to its boron content. In the field of medicine, boron compounds also show unique biological activities. Some boron drugs are being developed for cancer treatment. Boron neutron capture therapy is used to precisely kill cancer cells. < Br >
2-Furanylpyruvate is widely used in the field of organic synthesis. As a key intermediate, it can participate in the construction of many complex organic compounds. Taking the synthesis of specific drug molecules as an example, 2-Furanylpyruvate can use its special structure to combine with other functional groups through a series of chemical reactions to build the skeleton of the target drug. At the same time, in the synthesis of fragrances, it can also play a role in imparting a unique aroma to fragrances.
Methyl 3-hydroxyacetate is an important raw material in chemical production. It can be used to prepare a variety of fine chemicals, such as some special esters. In the paint industry, its participation in the synthesis of resins can improve the properties of coatings, such as improving the adhesion and weather resistance of coatings. In the cosmetic field, methyl hydroxyacetate can be converted into related ingredients through a specific process for use in skin care products, with certain skin conditioning effects.

In today's world, business conditions are unpredictable, and the market prices of 5-hydroxytryptamine, 2-aminopyridine, and 3-ethyl glutamate also fluctuate with many reasons.
Guanfu 5-hydroxytryptamine, a key raw material for neurotransmitter synthesis, is used in medicine, chemical industry and other fields. Its market price often depends on the abundance of raw materials, the difficulty of the process, and the amount of need. If the raw materials are widely sourced and the process is advanced, the supply may exceed the demand, and the price may stabilize and decline; conversely, if the raw materials are scarce, the preparation is difficult, and the demand is large, the price will rise.
As for 2-aminopyridine, it is mostly used in organic synthesis and pharmacy. Its market price is related to the status of upstream and downstream industries. If the supply of upstream raw materials is smooth, there are many production enterprises, and the competition is fierce, the price may be cheap; if the upstream changes, the supply is tight, and the downstream demand is strong, the price will rise.
Re-discussion of ethyl glutamate 3 is very important in the food and pharmaceutical industries. The change in its price is also linked to the cost of raw materials, regulations and policies, and market preferences. The cost of raw materials is high, the cost of compliance increases, and the market is good, the price must be high; if the raw materials are easy to obtain, the policy is favorable, and the market demand is controlled, the price may be controllable.
All in all, the market prices of these things are not static. As a businessperson, one must carefully observe the market and gain insight into changes in supply and demand in order to obtain the trend of their prices and seek business prosperity.

The storage conditions of 5-hydroxy2-furanopyruvate and ethyl 3-hydroxybutyrate are crucial for maintaining their quality and effectiveness.
These two should be stored in a cool, dry and well-ventilated place. A cool environment can slow down its chemical reaction rate and avoid decomposition and deterioration of components due to excessive temperature. Generally speaking, the temperature should be controlled below 20 degrees Celsius, preferably 10 to 15 degrees Celsius. If the temperature is too high, 5-hydroxy2-furanopyruvate may undergo molecular structure rearrangement, and ethyl 3-hydroxybutyrate may also accelerate hydrolysis due to heat, which may damage its inherent characteristics.
Dry conditions are also key. Moisture can easily lead to deliquescence, or cause adverse reactions such as hydrolysis and oxidation. The ambient humidity should be maintained at 40% - 60%. Desiccants, such as silica gel, can be used to absorb moisture in the storage container to keep it dry.
In addition, the two should be protected from light. Light, especially ultraviolet light, has high energy and can lead to photochemical reactions. 5-Hydroxy-2-furanylpyruvate and 3-hydroxybutyrate ethyl ester are exposed to light, or cause intramolecular electron transitions, causing structural changes and reducing their purity and activity. Therefore, it is often stored in dark containers such as brown bottles and stored in the dark.
In addition, 5-hydroxy- 2-furanylpyruvate and 3-hydroxybutyrate ethyl ester may have certain volatility and chemical activity, and need to be sealed for storage. Sealing can prevent its volatilization and escape, and avoid reaction with oxygen, carbon dioxide and other components in the air. After taking it, it should be sealed immediately to ensure its stable quality.
When storing, it is also necessary to prevent mixing with other chemicals. Because of its chemical properties, or react with other substances. Such as 5-hydroxy- 2-furanylpyruvate acid, do not store with alkaline substances; 3-hydroxybutyrate ethyl ester has ester properties, avoid contact with strong acids and alkalis. Therefore, it must be properly stored to ensure its long-term and stable quality.