Methyl 3-methylpyridine-2-carboxylate

Methyl-3-methylpyridine-2-carboxylic acid esters have a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique chemical structure, many other organic compounds can be derived through various reaction paths.
For example, by reacting with nucleophiles, the functionalization of the pyridine ring can be achieved, resulting in the preparation of organic molecules with special properties, which is of great significance in the field of medicinal chemistry. In drug development, chemists often need to construct complex and bioactive molecular structures. Methyl-3-methylpyridine-2-carboxylic acid esters can be used as starting materials to gradually build the required drug molecular skeleton through a series of delicate reactions.
Furthermore, in the field of materials science, it also has its uses. After specific chemical modifications, it may be introduced into polymer materials to improve the properties of materials. Such as improving the stability and solubility of materials, or even imparting specific optical and electrical properties to materials.
In addition, it is also a common raw material in the preparation of fine chemical products. Fine chemical products cover a variety of categories such as fragrances and dyes. Methyl-3-methylpyridine-2-carboxylic acid esters can participate in the synthesis process by virtue of their unique chemical properties, giving the products unique characteristics.

Methyl-3-methylpyridine-2-carboxylic acid ester, this substance is an organic compound. Its physical properties are quite characteristic.
Looking at its appearance, it is often a colorless to light yellow liquid, with a clear and transparent texture, and a soft luster in the sun, like a quiet stream. Smell its smell, with a specific aroma, although not strong and pungent, it is unique, like a unique fragrance hidden in a hundred flowers.
Talking about the melting point, the melting point is low, it is difficult to solidify at room temperature, and it always maintains a flowing state, just like a smart dancer who never stops. The boiling point is within a certain range, and specific conditions are required to make it gasify and transform it into a gaseous state floating in the air. < Br >
Solubility is also an important property. It can blend well in organic solvents such as ethanol and ether, just like a fish entering water and being free. However, when it meets water, it is difficult to dissolve, and the boundaries between the two are clear, just like the Chu River and the Han River, each guarding one side.
Compared with water, the density may be different, and its specific value can be known through accurate measurement, so that it can be clearly distinguished among many liquids. These many physical properties are like their unique "business cards", helping people to accurately understand and grasp this object in the field of chemistry.

Methyl-3-methylpyridine-2-carboxylic acid ester, this is an organic compound with interesting chemical properties.
First of all, its physical properties are mostly liquid or solid at room temperature, with specific melting points and boiling points. In terms of solubility, it has good solubility in organic solvents, such as ethanol and ether, but poor solubility in water. Due to the limited polar groups in the molecular structure, it interacts weakly with water molecules.
In terms of chemical activity, the ester group in this compound is chemically active. It can undergo hydrolysis reactions. In acidic or alkaline environments, the ester group will be disconnected. Under acidic conditions, 3-methylpyridine-2-carboxylic acids and methanol will be formed; under alkaline conditions, 3-methylpyridine-2-carboxylate and methanol will be formed.
In addition, the pyridine ring also imparts different chemical properties to this compound. The pyridine ring is rich in electrons and can participate in electrophilic substitution reactions, but the reactivity is slightly lower than that of the benzene ring. Due to its strong electronegativity of the nitrogen atom, it will attract electron clouds, which will reduce the density of the electron clouds on the pyridine ring. In electrophilic substitution reactions, the substituents tend to enter the 4th or 5th position of the pyridine ring.
At the same time, the methyl group in this compound is not inactive. Methyl groups can undergo oxidation reactions and can be converted into carboxyl groups or other oxygen-containing functional groups under the action of appropriate oxidants.
This compound is widely used in the field of organic synthesis and can be used as an intermediate to prepare a wide variety of pyridine derivatives. It has important value in many fields such as medicinal chemistry and materials science.

There are several methods for synthesizing methyl 3-methylpyridine-2-carboxylic acid esters. One method is to use 3-methylpyridine-2-carboxylic acid as the starting material, so that it can be esterified with methanol under acid catalysis. In this process, strong acids such as sulfuric acid and p-toluenesulfonic acid are often used as catalysts, and reflux is heated at an appropriate temperature. During the reaction, attention should be paid to the control of temperature. If it is too high, it is easy to cause side reactions to occur, which affects the purity and yield of the product.
Another method can first convert 3-methylpyridine-2-carboxylic acid into its acid chloride form, and react with reagents such as dichlorosulfoxide. The resulting acid chloride is then reacted with methanol to obtain the target product. The advantage of this approach is that the reaction activity is high and the reaction process is relatively easy to control.
In addition, the corresponding pyridine derivatives are used as raw materials to construct carboxyl groups and methyl groups through multi-step reactions, and finally form esters. First, a suitable functional group is introduced at a specific position on the pyridine ring, and the desired structure is gradually constructed through reactions such as halogenation and metal-organic reagent coupling. Finally, methyl 3-methyl pyridine-2-carboxylic acid ester is obtained through esterification steps. Although this path is slightly complicated, the synthesis strategy can be flexibly adjusted according to different starting materials and reaction conditions to achieve the purpose of optimizing the product.

I have not heard of the exact price range of "Methyl+3-methylpyridine-2-carboxylate" in the market. The price of this compound may vary due to quality, purity, supply and demand. If it is in the market of chemical raw materials, the price will be very high; if the quantity is small and the demand is thin, the price may fluctuate.
To know the price, you can go to the platform of chemical raw material trading, such as Mobell, etc., and look at the quotation of various merchants. However, the price is not constant, and it varies from time to time due to market conditions. Or ask chemical product suppliers, they can often tell the price range according to the current situation.
However, I have no exact price for you, but I hope this way can help you get the price of this compound. You can follow the above way and seek for it yourself, and you will definitely get a price close to the real one.