Isopropyl 6-Cyano-5-methoxycarbonyl-2-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

The specific explanation of the chemical name of this product is to explore the specific title and detailed connotation of the product in the field of chemistry. The chemical name is of great significance for clarifying its chemical composition, characteristics and reaction mechanism as a precise identification and definition of substances.
Looking at "Tiangong Kaiwu", although it is not explained in modern chemical terms, it also has exquisite expressions for many substances. For example, when it comes to metal smelting, it is called "gold, silver, copper, iron, tin", etc. This is the simple cognition and naming of metal substances by the ancients. For metal ores, there are also related names, such as "calamine" (mainly containing zinc carbonate). The ancients knew that it could smelt zinc. Although it has not been accurately analyzed by modern chemistry, this title reflects the cognition of the use and characteristics of the substance at that time.
Another example is the method of making salt in the book, which also describes the names and characteristics of different salts. "Sea salt", "well salt" and "pool salt" are named according to the source. Although they do not involve chemical structure, they are distinguished from a practical point of view. From the perspective of modern chemistry, salt is a kind of metal ion or ammonium ion and acid ion binding compound, which is a precise chemical definition.
Another example is the mention of "alum" substances, such as "green alum" (ferrous sulfate crystal). The ancients knew its characteristics and uses, such as being used for dyeing mordant dyeing, etc. Although their precise chemical composition is unknown, the name "green alum" is conventional, reflecting the cognition of the color, morphology and other characteristics of the substance.
In summary, the specific explanation of the chemical name of the product is precisely defined in the modern chemical system, and the essence of matter is analyzed from the microscopic atomic and molecular levels. Although the ancients did not reach this depth, their naming method based on practical observation laid the foundation for later chemical research and reflected the evolution of material cognition in different eras.

Isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid ester is mostly used in the field of medicinal chemistry. Its main use is in the development of new cardiovascular drugs.
The world is often disturbed by cardiovascular diseases. And such dihydropyridine derivatives have unique pharmacological activities. It can effectively regulate the calcium ion channel on the cell membrane, just like a delicate key to open and close the path of ions in and out. In this way, the contraction and relaxation of myocardial cells can be more orderly, and the pumping power of the heart can be stabilized. It can also relax the smooth muscle of the blood vessels, relax the blood vessels, lower the blood pressure, and reduce the load on the heart.
And it is also beneficial in the prevention and treatment of ischemic heart disease. When myocardial ischemia occurs, it can improve the energy metabolism of the myocardium, supply energy to the myocardial cells, and enable them to maintain normal function in ischemic difficulties, reduce the risk of myocardial infarction, and protect the well-being of the heart. Therefore, in the process of cardiovascular drug creation, isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylate is a promising "good material" for doctors to treat cardiovascular diseases.

If a product has extraordinary characteristics, it often shows a unique quality at the physical and chemical level. Looking at "Tiangong Kaiwu", it contains the properties of many things in detail. Today, the ancient text describes the characteristics of this product as follows.
On the physical properties, its color may show a distinct state, or it may show a simple color, just like a natural touch. Its shape, or regular and orderly, seems to conform to the laws of heaven and earth; or quirky and changeable, like the random nature of creation. Touch it, the texture may be warm and delicate, as smooth as suet jade; or solid and hard, just like the indestructible of gold and stone. And its density is also different. The heavy ones are calm and heavy, as if carrying the precipitation of time; the light ones are light and seem to be able to dance with the wind, showing agility.
As for the chemical properties, under ordinary environments, it may have excellent stability, as if it can resist the erosion of time, and it will not change its quality after years. Encounter various chemical reagents, or react quietly with them to generate novel things and show different chemical changes; or stick to themselves, unmoved, showing their chemical inertia. Its ignition point also varies from high to low. The high ones can still hold themselves in the midst of fire and are not easy to burn; the low ones burn when they encounter open flames, blooming gorgeous flames, and releasing unique odors and heat at the same time.
Such a variety of physical and chemical properties make this product unique in the world, or can be used for various skills and life needs, which is a wonder of the combination of creation and artificiality.

The method of synthesizing isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid esters relies on the classical organic synthesis techniques in the past.
First, 3-nitrobenzaldehyde, isopropyl acetoacetate, methyl cyanoacetate and ammonia source are used as starting materials. In a suitable reaction medium, it is obtained through a condensation cyclization reaction. During the reaction, the temperature, pH and reaction time need to be carefully controlled. If the temperature is too high, side reactions will multiply; if the temperature is too low, the reaction will be slow. PH is also the key, and either peracid or peralkali can cause the reaction direction to deviate. The reaction time also needs to be precisely controlled. If it takes a long time, the product will decompose, and if it is short, the reaction will not be completed.
Second, the multi-component one-pot method is adopted. The above several raw materials are added to the same reactor, and an appropriate amount of catalyst, such as an organic base or Lewis acid, is added to make a ring in one step. This method is simple and fast, but it requires strict reaction conditions. The type and dosage of catalyst have a great impact on the yield and purity of the product. Improper catalyst selection may lead to poor reaction selectivity and increased product impurities.
Third, the improved synthesis path can utilize transition metal catalysis. For example, metal complexes such as palladium and copper are used as catalysts to optimize reaction conditions and improve reaction efficiency and selectivity. However, this path requires high reaction equipment and operation, metal catalysts are expensive, and catalyst residues need to be properly handled to avoid affecting product quality.
All this synthesis method has advantages and disadvantages. Although the classical condensation cyclization method has clear steps, it is cumbersome to operate; the multi-component one-pot method is convenient and efficient, but the conditions are difficult to control; although the transition metal catalysis method has advantages, the cost and operation difficulties should not be underestimated. To obtain products with high yield and high purity, it is necessary to weigh the advantages and disadvantages according to the actual situation and choose carefully.

Isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid esters are commonly used in the market. What are the specifications? And listen to my ancient words.
This compound is on the market, and the specifications are often related to its quantity and quality. Quantity, or a small amount, in grams, such as 1 gram, 5 grams, 10 grams, it is easy for researchers to use, and it is used for initial research in the laboratory. A small amount is enough for it to explore physical properties and test its reaction. There are also larger quantities sold, such as hundreds of grams or even kilograms, suitable for pre-industrial expansion tests, or occasions where there is a greater demand for them.
Quality, related to purity. Common high purity, such as purity of 95%, 98% or even more than 99%, this kind is suitable for reactions sensitive to impurities, or pharmaceutical, fine chemical and other fields, requiring precise ingredients. There are also relatively low purity, such as about 90%, or due to cost considerations, it is used in industrial processes with slightly wider requirements, which can meet some general production needs and reduce its cost.
There are different packaging specifications. Or bottled, small bottles can hold a small amount of samples, and large bottles can hold more. It is also packed in bags for easy transportation and storage. Its packaging may be sealed to prevent moisture and oxidation, to ensure the stability of this compound, so that it does not lose its properties when it circulates between cities.