Isobutyl 1,4-Dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(2-nitrophenyl)-3-pyridinecarboxylate

Isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridine carboxylic acid ester is widely used. In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Because of its unique molecular structure, it can interact with specific targets in organisms, which helps to develop drugs with specific curative effects, such as for some difficult diseases, or by modifying its structure, it can develop drugs with better curative effects and less side effects.
It also plays an important role in the field of organic synthesis. As a key synthetic building block, chemists can use a series of chemical reactions to derive more complex and functional organic molecules, which can contribute to the development of organic synthetic chemistry. For example, when building organic compounds with specific optical, electrical or material properties, they can be used as starting materials to achieve the synthesis of target molecules through ingenious reaction strategies.
In the field of materials science, materials based on or derived from these substances, or with special physical and chemical properties, are expected to be applied to fields such as optical materials and electronic materials, providing new opportunities for the innovative development of materials science.

The synthesis method of isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridine carboxylic acid ester, although the ancient book "Tiangong Kaiji" does not contain this specific compound synthesis method, it contains the principle of creation, which can be used for reference. To synthesize this compound today, a compound containing a pyridine structure is often used as the starting material.
Or take a suitable pyridine derivative first, whose structure needs to be similar to the target product pyridine ring. In the method of fine chemistry, methyl and other substituents are introduced at specific positions of the pyridine ring. For example, by nucleophilic substitution or condensation reaction, methyl can be introduced at the 2nd and 6th positions. Then, 2-nitrophenyl is introduced at the 4th position. This step requires fine control of the reaction conditions, or palladium-catalyzed coupling and other reactions to make the two accurately connected.
As for the introduction of 5-methoxycarbonyl, or after the construction of the pyridine ring is completed, it is obtained by reacting with methoxycarbonyl-containing reagents, such as the reaction of the corresponding ester with the pyridine derivative, through substitution or addition elimination. < Br >
to connect isobutyl, after the main structure of the pyridine ring and other substituents are complete, the halogenated hydrocarbons or alcohols containing isobutyl are selected. Under basic or catalytic conditions, the nucleophilic substitution and other reactions, the isobutyl is attached to the specific position of the pyridine ring, and the final isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridine carboxylic acid ester. The synthesis path is non-uniform, and it should be used according to the raw materials, equipment and reaction conditions.

Isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridyl carboxylate, this physical property is also quite complex. Its color state, at room temperature, may be a colorless to light yellow oily liquid, or a white-like solid. It has no specific color and fragrance, but the subtleties need to be carefully observed.
As for its melting point, due to the unique molecular structure, it is in a specific range. The exact number of this range is determined by fine experiments, but external factors such as purity, measurement instruments and methods can cause it to change slightly. The boiling point is also an important physical property to consider. Under normal pressure, the boiling temperature also has a certain value, which is the result of the combined action of many factors such as intermolecular forces and structural stability.
Solubility is also one of the key physical properties. In organic solvents, such as ethanol and acetone, it may have good solubility, because the groups contained in the molecular structure can form specific interactions with the molecules of organic solvents, such as hydrogen bonds, van der Waals forces, etc., so it is soluble. In water, due to the existence of hydrophobic groups, dissolution is quite difficult, only slightly soluble or insoluble. < Br >
In terms of density, its value reflects the compactness of the substance. Compared with other compounds with similar structures, it has its own unique density value. This value is also affected by factors such as temperature. When the temperature increases, the density generally decreases slightly.
The refractive index of this substance can reflect its influence on light propagation, and it is also an important physical constant. The determination of its value requires professional equipment under specific conditions, and the accuracy of the measurement results is related to the cognition of its structure and purity.
All these properties are the key to in-depth understanding of isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridyl carboxylic acid esters, which can provide an important basis for their application, synthesis, separation and many other fields.

Isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridine carboxylic acid ester, which is an organic compound. Looking at its structure, it contains a pyridine ring, and there are many substituents on the ring, such as methoxycarbonyl, dimethyl, nitrophenyl, etc., and the side chain is connected with isobutyl.
Its chemical properties, due to the ester group, can occur hydrolysis reaction. Under acidic or basic conditions, the ester bond is easily broken, and the corresponding carboxylic acid and alcohol are obtained by acidic hydrolysis, and the carboxylate and alcohol are obtained by alkaline hydrolysis. < Br >
Because of its pyridine ring, it is aromatic and can participate in the electrophilic substitution reaction. However, the nitrogen atom of the pyridine ring has electron-absorbing properties, which reduces the electron cloud density on the ring, the electrophilic substitution activity is weaker than that of the benzene ring, and the reaction check point is mostly at the β-position.
Furthermore, the nitro group on the benzene ring is a strong electron-absorbing group, which decreases the electron cloud density of the benzene ring, which affects the electron cloud distribution of the pyridine ring connected to it, and also has an effect on the reactivity of the whole molecule.
The alkyl group in the molecule has a slight increase in the electron cloud density of nearby groups due to its electron-giving induction effect, and also has a subtle effect on the reactivity.

I don't know what the market price of "isobutyl-1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (2-nitrophenyl) -3-pyridyl carboxylate" is. This is a very professional and uncommon chemical substance, and its price may vary greatly due to factors such as purity, output, and market demand.
If this substance is a common chemical raw material, in the general chemical market, its price may vary according to quantity, and if the quantity is large, the price will be better, but it also depends on its supply and demand. If its production process is complicated, the raw materials are rare, or the price may be high.
If it is a special laboratory reagent, its price may be higher. Due to the difficulty of preparation and mostly small production, it is necessary to take into account the costs of research and development, purification, etc.
And because I do not have real-time market information, it is difficult to determine its specific price. If you want to know the details, you can consult chemical product suppliers, reagent sales platforms, or visit people in the industry at chemical industry forums. They may be able to tell you the approximate price range of this substance based on their personal experience and market insights.