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What are the chemical properties of imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-
Alas! The chemical properties of this "6-chloro-imidazolo [1,2-a] pyridine-8-carboxylic acid" are particularly important. This compound is acidic, and because it contains a carboxyl group (-COOH) functional group, this carboxyl group can release protons. Under suitable conditions, it can neutralize with bases to generate corresponding salts and water.
Looking at its halogen atom, the 6-position chlorine atom endows this molecule with unique reactivity. The chlorine atom has a high electronegativity, which can affect the electron cloud distribution of the molecule, causing the electron cloud density of the carbon atom in the ortho or para-position to decrease, making this part more susceptible to attack by nucleophiles, thereby triggering nucleophilic substitution reactions.
In the field of organic synthesis, this compound may be used as a key intermediate. The skeleton structure of imidazolopyridine is widely present in many bioactive molecules and drugs. By chemically modifying it, new compounds with specific pharmacological activities can be created. And because it contains chlorine atoms and carboxyl groups, it can undergo a variety of organic reactions, such as esterification, amidation, etc., to construct more complex molecular structures.
Furthermore, its physical properties are also worthy of attention. Its solubility may vary depending on the polarity of the molecule. The carboxyl group enhances the polarity of the molecule, or makes it soluble in polar solvents (such as water and alcohols). However, the presence of aromatic rings in the molecule may also make it soluble in non-polar solvents (such as hydrocarbons). This solubility characteristic needs to be carefully considered during its separation, purification and application.
What are the main uses of imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-
Imidazolo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-this substance has a wide range of uses. In the field of medicine, it is a key intermediate for the preparation of specific drugs. Its unique structure can precisely bind to specific targets in organisms, thereby regulating physiological processes, and laying the foundation for the development of innovative drugs for the treatment of specific diseases.
In the field of pesticides, with its unique mechanism of action against pests, it can be made into high-efficiency and low-toxicity pesticides. It can interfere with the normal physiological activities of pests, or inhibit the growth and reproduction of pathogens, providing a strong guarantee for agricultural production, helping to reduce pest infestation, and improve crop yield and quality.
In the field of materials science, this compound can be introduced into polymer materials through specific reactions to give the material unique properties. Such as improving the thermal stability and mechanical properties of materials, broadening the application range of materials, and showing its talents in high-end fields such as aerospace and electronic equipment.
In addition, in the field of chemical synthesis, as an important building block for organic synthesis, many novel compounds can be derived through various chemical reactions, greatly enriching the variety of organic compounds, injecting vitality into the development of organic synthesis chemistry, and promoting the continuous exploration of chemistry. In short, imidazolo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-have indispensable location and important application value in many fields.
What is the synthesis method of imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-
To prepare 6-chloro-imidazolo [1,2-a] pyridine-8-carboxylic acid, the method is as follows:
First, with suitable starting materials, such as compounds containing pyridine and imidazole structures, both of which need to have reactive functional groups to lay the foundation for subsequent reactions.
Then, the chlorination reaction is carried out. Select suitable chlorination reagents, such as thionyl chloride, phosphorus oxychloride, etc. Under appropriate reaction conditions, such as suitable temperature and solvent environment, the chlorination reagent can fully interact with the starting material. The temperature may be controlled within a certain range to prevent side reactions from happening, and the solvent should be selected with good solubility of the raw material and the reagent to make the reaction proceed uniformly. After this chlorination reaction, a chlorine atom is introduced at a specific position in the pyridine ring, that is, at position 6.
Then, the chlorinated product is carboxylated. Specific carboxylation reagents can be used, such as a combination of carbon dioxide and metal reagents. Under specific reaction conditions, the reagent is reacted with the chlorinated product, and the carboxyl group is successfully introduced at position 8 of the imidazolo [1,2-a] pyridine structure. This process requires fine regulation of reaction conditions, such as reaction time, temperature, and reactant ratio, to increase the yield and purity of the target product. After the reaction is completed, a series of post-processing steps, such as extraction, washing, recrystallization, etc., are used to purify the product to obtain a high-purity 6-chloro-imidazolo [1,2-a] pyridine-8-carboxylic acid.
Imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro- what is the price range in the market
I don't know what the price range of this "imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro -" is in the market. The price of various items in the market often changes due to many reasons, such as the abundance of materials, the difficulty of making art, the amount of purchase, the passage of time, and the price may vary from place to place and different merchants.
If you want to know the exact price of this item, you should consult the firm specializing in this chemical material, the pharmaceutical company, or the platform and information of chemical material trading, and look at the price of its recent transactions. There is no detailed evidence today, and it is difficult to determine its price range in the market.
What are the manufacturers of imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-
It is not easy to know the manufacturer of imidazo [1,2-a] pyridine-8-carboxylic acid, 6-chloro-. In today's world, chemical production is complex and diverse, and the manufacturers of this compound are also scattered everywhere.
There may be a large chemical giant with excellent equipment and technology, or it may be able to produce this product. If you want to know for sure, you must consult the chemical directory, industry information, or ask the experts in the chemical industry.
In the chemical directory, you should read it carefully, examine it line by line, or find the names of one or two manufacturers. Industry information is also an important way, and new companies and R & D progress can be known here. In the chemical industry, after years of hard work, I have a wide range of knowledge, or I can show the way.
However, it is difficult for me to immediately specify the specific manufacturer. This compound may be used in the fields of fine chemicals, pharmaceutical research and development, etc., and all related companies have the possibility of production. It is necessary to be patient, careful, and explore in many ways, or to get accurate information. Hope you can visit diligently and finally get the manufacturer information you need.