Imidazo 1 2 A Pyridine 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

imidazo[1,2-a]pyridine-2-carboxylate

    Specifications

    HS Code

    575878

    Chemical Formula C9H8N2O2
    Molar Mass 176.17 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point Varies depending on purity
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Pka There are acidic and basic sites with different pKa values related to the functional groups
    Uv Vis Absorption Absorbs in certain UV regions due to conjugated systems
    Ir Absorption Peaks Characteristic peaks for C=O, C - N, and aromatic C - H bonds

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    Frequently Asked Questions

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    What is the chemical structure pyridine-2-carboxylate imidazo [1,2-a]
    Imidazo [1,2-a] pyridine-2-carboxylate is imidazo [1,2-a] pyridine-2-carboxylate, and its chemical structure is as follows.
    The core structure of this compound is imidazo [1,2-a] pyridine, which is formed by fusing an imidazole ring with a pyridine ring. The imidazo ring is a five-membered heterocycle containing two nitrogen atoms; the pyridine ring is a six-membered heterocycle containing one nitrogen atom. The two rings are fused in a specific way to form a unique fused ring system. In the second position of the fused ring system, a carboxylate group is connected. In this carboxylate part, its carboxylate anion binds to metal ions or other cations to form a corresponding salt.
    For example, when combined with sodium ions, imidazolo [1,2-a] pyridine-2-carboxylate sodium salt is formed. This chemical structure endows the compound with specific physical and chemical properties, and shows important value in the fields of organic synthesis and medicinal chemistry. It can be used as a key intermediate in the synthesis of compounds with specific biological activities, or participate in the construction of complex organic molecular structures, promoting research and development in related fields.
    What are the main physical properties of imidazo [1,2-a] pyridine-2-carboxylate?
    Imidazolo [1,2-a] pyridine-2-carboxylate, this is a class of organic compounds with many unique physical properties.
    Its appearance is often a crystalline solid state, mostly white or nearly white. The fine crystal structure gives it a delicate texture, and it occasionally shines under light.
    Melting point is one of the key physical properties. Different substituents can cause melting point differences, usually in a relatively high temperature range, such as partial imidazolo [1,2-a] pyridine-2-carboxylate melting point or between 150 ° C and 300 ° C. The higher melting point is due to the strong interaction between molecules, such as hydrogen bonds, van der Waals forces, etc., so that the molecules are closely arranged, and more energy is required to destroy the lattice and cause it to melt.
    Solubility is also an important property. In common organic solvents, such as ethanol, acetone, etc., the substance exhibits a certain solubility. In polar organic solvents, molecules and solvent molecules can form hydrogen bonds or other interactions, so they can be dissolved. However, the solubility in water is relatively limited, because the hydrophobic part of the molecular structure accounts for a large proportion, which hinders its full interaction with water molecules.
    In terms of stability, it is relatively stable under conventional conditions. However, in case of extreme conditions such as strong acid, strong base or high temperature, strong oxidant, etc., its structure may change. Because its molecular structure contains heterocyclic and carboxylate groups, it has a certain sensitivity to acid and alkali. In case of strong acid, carboxylate groups or protonation; in case of strong base, some check points on the heterocyclic ring or attack, causing structural changes.
    In addition, the substance has a certain thermal stability, and under moderate heating conditions, the structure and properties remain unchanged. However, if the temperature is too high, the chemical bonds in the molecule may break, triggering decomposition reactions.
    In summary, the physical properties of imidazolo [1,2-a] pyridine-2-carboxylate, such as appearance, melting point, solubility and stability, are determined by its unique molecular structure, and these properties have a profound impact on its application in organic synthesis, medicinal chemistry and other fields.
    Imidazo [1,2-a] pyridine-2-carboxylate in which areas
    Imidazo [1,2-a] pyridine-2-carboxylate (imidazo [1,2-a] pyridine-2-carboxylate) is used in various fields.
    In the field of medicine, it is often a key component in the creation of new drugs. Due to its unique structure, it can be combined with biological macromolecules such as proteins and enzymes in the body in a specific way. Therefore, imidazo [1,2-a] pyridine-2-carboxylate is often regarded as a lead compound with extraordinary potential when developing antiviral, anti-tumor and anti-inflammatory drugs. By modifying and optimizing its structure, innovative drugs with better curative effect and less side effects can be obtained.
    In the field of materials science, there are also traces. Because of its certain optical and electrical properties, it may be applied to the preparation of functional materials. For example, in the development of organic Light Emitting Diode (OLED) materials, its unique structure may be used to improve the luminous efficiency and stability of the materials, contributing to the development of display technology.
    In the field of pesticides, imidazo [1,2-a] pyridine-2-carboxylate has also emerged. After research, it has been found that it has the effect of inhibiting and killing some pests and bacteria. New pesticides developed on this basis may reduce the adverse impact on the environment while ensuring crop yield, and meet the current needs of green agriculture development.
    In summary, imidazo [1,2-a] pyridine-2-carboxylate has important application value in many fields such as medicine, materials science, and pesticides, and is actually a class of compounds worthy of in-depth investigation and development.
    What are the synthesis methods of imidazo [1,2-a] pyridine-2-carboxylate
    The synthesis of imidazolo [1,2-a] pyridine-2-carboxylate is a key exploration in the field of chemical synthesis. Its synthesis pathways are diverse, and different starting materials and reaction routes can be started.
    First, the pyridine derivative is used as the starting material. First, the pyridine derivative is reacted with a suitable reagent under specific conditions, and the imidazole ring structure is introduced. This process often requires a suitable catalyst, reaction temperature and time to control. For example, in an inert gas-protected atmosphere, pyridine derivatives are combined with specific nitrogen-containing reagents, under the action of a catalyst such as a copper salt, in a suitable organic solvent, heated to a certain temperature and maintained for several hours to promote the construction of an imidazole ring, and then through carboxylation reaction, carboxyl groups are introduced to form salts to obtain imidazolo [1,2-a] pyridine-2-carboxylate.
    Second, starting from imidazole derivatives. React imidazole derivatives with reagents with pyridine structure fragments. This reaction also requires precise regulation of reaction conditions, such as the selection of an appropriate base as a catalyst, to control the pH of the reaction system. In the process of gradual heating from low temperature to room temperature, let the two fully react to construct the pyridine part, and then modify the carboxyl group and form a salt to complete the synthesis of the target product.
    In addition, a multi-step tandem reaction strategy can also be used. A variety of simple reactions are cleverly connected in series, and a complex imidazo [1,2-a] pyridine-2-carboxylate structure is gradually constructed from the basic raw materials. This method requires effective control and transformation of the intermediate of each step of the reaction to ensure the smooth progress of the reaction and the purity of the product. In short, there are many methods for synthesizing imidazo [1,2-a] pyridine-2-carboxylate, and the optimal synthesis route needs to be weighed according to actual needs and conditions.
    Imidazo [1,2-a] What is the market outlook for pyridine-2-carboxylate?
    Imidazo [1,2-a] pyridine-2-carboxylate, Chinese name imidazo [1,2-a] pyridine-2-carboxylate, has emerged in the fields of medicine and pesticides, and its market prospect is like the rising sun, full of hope and potential.
    Looking at the field of medicine, in recent years, the research on neurological diseases and cancer treatment has been shining brightly. Imidazo [1,2-a] pyridine-2-carboxylate can precisely act on specific biological targets due to its unique chemical structure and biological activity, just like a delicate key matching an exclusive lock. Therefore, it has attracted much attention in the research and development of new drugs, just like a shining star, attracting many pharmaceutical companies and scientific research institutions to invest in research and development resources. Over time, it is very likely to give rise to innovative drugs and bring good news to patients, and the market demand will surely be like water in a river.
    As for the field of pesticides, with the increasing emphasis on the quality, safety and environmental protection of agricultural products, the development of high-efficiency, low-toxicity and environmentally friendly pesticides is imminent. The biological activity of imidazo [1,2-a] pyridine-2-carboxylate makes it unique in the design of new pesticides, which may effectively kill pests, inhibit bacteria, and reduce the negative impact on the environment. Like a breeze, it has injected new vitality into the pesticide market, the market prospect is bright, and the demand will also rise steadily.
    However, the road to market expansion is not smooth sailing. The complexity of the synthesis process is like a mountain that is difficult to climb, resulting in high production costs, which limits its large-scale promotion and application to a certain extent. However, with the progress of science and technology, like a magic weapon, new synthesis methods or technologies are expected to break through this dilemma. Once the cost is effectively controlled, its market scale will surely spread its wings like Kunpeng and skyrocket.
    In summary, imidazo [1,2-a] pyridine-2-carboxylate is currently facing challenges, but with its huge potential in the field of medicine and pesticides, the market prospect is undoubtedly very broad, and it will definitely be able to write a brilliant chapter in related industries in the future.