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What is the main use of this product imidazo [1,2-a] pyridine, 2-bromo-
This is a compound called 2-bromo-imidazolo [1,2-a] pyridine. It has a wide range of uses and is often a key intermediate in the synthesis of many biologically active drug molecules in the field of medicinal chemistry. Many studies have shown that compounds containing this structure exhibit high affinity and activity for specific biological targets. For example, in the development of drugs related to neurological diseases, the structure of this compound can be modified to obtain new drugs that regulate certain neurotransmitter receptors.
In the field of materials science, this compound also has its uses. Due to its special molecular structure, it has certain optical and electrical properties and can be applied to the preparation of organic optoelectronic materials. By combining with other organic or inorganic materials, the luminescence, electrical conductivity and other characteristics of the material can be optimized. For example, in the design of organic Light Emitting Diode (OLED) materials, the introduction of this structure can improve the luminous efficiency and stability of the material.
Furthermore, it also plays an important role in pesticide chemistry. Some compounds derived from 2-bromo-imidazolo [1,2-a] pyridine have significant inhibitory or killing effects on specific pests or bacteria, and can be developed as active ingredients of new pesticides, providing new ways and methods for agricultural pest control.
What are the physical properties of imidazo [1,2-a] pyridine, 2-bromo-
2-Bromo-imidazolo [1,2-a] pyridine, this is an organic compound. Its physical properties are quite critical, let me explain in detail.
Looking at its appearance, it is often white to light yellow crystalline powder, fine and uniform. This morphology is used in many organic synthesis reactions, which is conducive to its dispersion and participation in the reaction, just like a fine material, laying a good foundation for subsequent reactions.
When it comes to the melting point, it is about a specific temperature range. This property is of great significance for the determination of the purity of the compound and its stability under different temperature conditions. It is like a precise temperature valve that controls the physical state transition of the compound.
Solubility is also one of the important physical properties. In common organic solvents, such as ethanol, dichloromethane, etc., it has a certain solubility. In ethanol, it can be dissolved at moderate temperatures, just like fish entering water and dispersing uniformly. This property is convenient for use as a reaction medium in organic synthesis, so that the reactants can be fully contacted and promote the smooth progress of the reaction. In water, its solubility is relatively weak, like oil droplets in water, and it is difficult to blend. This property also affects its application in different systems.
Furthermore, its density also has a specific value. This value determines its position distribution in the mixed system, just like the positioning coordinates of the substance in space, which is of great significance for chemical processes involving delamination, mixing and other operations.
In addition, the stability of the compound cannot be ignored. Under normal temperature and pressure, protected from light and moisture, it can maintain a relatively stable state. However, in case of special conditions such as high temperature and strong oxidants, its structure may change, just like a calm lake throwing boulders, triggering a chain reaction.
The physical properties of 2-bromo-imidazolo [1,2-a] pyridine are rich and diverse, and their properties are interrelated. They play an indispensable role in many fields such as organic synthesis and drug development.
What are the chemical properties of imidazo [1,2-a] pyridine, 2-bromo-
Eh! Fu2-bromo-imidazolo [1,2-a] pyridine is also an organic compound. Its chemical properties are quite interesting and should be examined in detail.
In this compound, the presence of bromine atoms endows it with unique reactivity. Bromine has strong electronegativity and is prone to participate in nucleophilic substitution reactions. Under appropriate conditions, nucleophilic reagents can attack it, causing bromine atoms to leave and generate new organic structures. For example, using alcohols as nucleophiles, under the catalysis of bases, bromine can be replaced by alkoxy groups to form ether derivatives. This reaction can expand its chemical synthesis path.
The parent nuclear structure of imidazolo [1,2-a] pyridine is also of great significance. The conjugated system makes the compound have certain stability and electronic characteristics. The nitrogen atom of the parent nucleus can act as an electron donor due to its lone pair of electrons, participate in coordination reactions, and complex with metal ions to form metal complexes, which may have applications in the field of catalysis.
And because of its special structure, it can be used as a key intermediate in organic synthesis. It can be used in many reactions, such as cyclization, addition, etc., to construct more complex organic molecules. The balance of its stability and reactivity provides a broad research space for chemists. It can be modified and transformed according to specific needs and different reaction conditions to obtain organic compounds with specific functions. It has potential value in medicine, materials and other fields.
What is the production process of imidazo [1,2-a] pyridine, 2-bromo-
In order to prepare 2-bromo-imidazolo [1,2-a] pyridine, the preparation process is particularly important.
At the beginning, suitable starting materials need to be selected. Pyridine derivatives and nitrogen-containing heterocyclic compounds are often used as bases, and the two can only initiate the key reaction steps under suitable reaction conditions.
Then, choose the appropriate reaction conditions. Temperature control is crucial. If it is too low, the reaction will be slow, and if it is too low, it may cause side reactions to cluster. Generally speaking, in a moderate heating environment, or in a specific heating range, the reaction can progress steadily. And the choice of solvent should not be ignored. A solvent with good solubility of the reactants and favorable for the reaction process should be selected to help the reactants fully contact and react.
As for the bromination step, bromine atoms should be introduced into the specific position of imidazolo [1,2-a] pyridine, that is, the 2-position. Suitable brominating reagents can be used, such as bromine, N-bromosuccinimide (NBS), etc. When using bromine, because of its activity, the operation needs to be cautious. In a suitable reaction system, slowly add dropwise to ensure that bromine atoms fall precisely on the target position. If NBS is used, the reaction is relatively mild and easier to control. It is also necessary to pay attention to the regulation of reaction conditions, such as reaction temperature, time, and the addition of catalysts.
catalysts may play an important role in this process. Some metal catalysts may accelerate the reaction rate and improve the selectivity of the reaction, so that bromine atoms are more inclined to be added to the 2-position. However, the dosage and type need to be tested many times and carefully selected.
After the reaction is completed, the separation and purification of the product should not be ignored. Often column chromatography, recrystallization, etc. are used to remove unreacted raw materials, by-products and impurities to obtain pure 2-bromo-imidazolo [1,2-a] pyridine, which is the final preparation process.
Imidazo [1,2-a] pyridine, 2-bromo - what is the price range in the market
At this time, I want to know the price of 2-bromo-imidazolo [1,2-a] pyridine in the market, but I have been searching for ancient books, but I have not been able to obtain an exact number. This is a thing in the world, and it was not available in ancient times, so it is difficult to explain its price in ancient words.
However, by common sense, the price of a thing in the market often changes for many reasons. The abundance of its raw materials, the difficulty of preparation, and the amount of demand can all make the price high or low. If the raw materials are easy to obtain, the method of preparation is simple, and there are few people who want them, the price may be cheap; on the contrary, if the raw materials are rare and complicated, and there are many people who need them, the price will be high.
Although I do not know the exact price of 2-bromo-imidazolo [1,2-a] pyridine today, if you want to know the details, you can go to today's pharmaceutical shops and chemical materials markets to consult merchants, or you can get an approximate price. Or search for relevant information on today's commercial information network, and you can get a recent price.
Although I cannot directly state its price in ancient words, the method of inferring it may help you know the clue of its market price.