H Imidazo 1 2 A Pyridine
pyridine pyrrole pyrazine piperidine piperazine

H-Imidazo[1,2-a]pyridine

    Specifications

    HS Code

    795601

    Chemical Formula C8H8N2
    Molar Mass 132.16 g/mol
    Appearance Solid
    Physical State At Room Temp Solid
    Melting Point N/A (depends on purity etc.)
    Boiling Point N/A (decomposes or high temp)
    Solubility In Water Poor
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol
    Density N/A (experimental determination needed)
    Pka N/A (specific value needs experimental measurement)
    Odor Typically odorless or faint
    Color Colorless to pale yellow

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    General Information
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    Frequently Asked Questions

    As a leading H-Imidazo[1,2-a]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of H-Imidazo [1,2-a] pyridine?
    H-imidazolo [1,2-a] pyridine, this is a kind of organic compound. Its molecular structure is unique, and it is formed by fusing the imidazole ring with the pyridine ring. The imidazole ring is a five-membered heterocyclic ring containing two nitrogen atoms, which is aromatic; the pyridine ring is a six-membered heterocyclic ring containing one nitrogen atom, which is also aromatic. The fused combination of the two makes the chemical properties and reactivity of the compound unique.
    Looking at its structure, the imidazole ring and the pyridine ring are connected by specific atoms to form a fused bilicyclic system. This structure endows the compound with many properties and is widely used in the fields of organic synthesis and medicinal chemistry. Due to its unique electron distribution and spatial structure, it can be used as a key intermediate to participate in many organic reactions and be used to construct more complex compounds. In drug development, such structures are often found in molecules with biological activity, or can be specifically bound to biological targets to exhibit pharmacological activity.
    In conclusion, the chemical structure of H-imidazolo [1,2-a] pyridine, due to the fused imidazole ring and pyridine ring, presents unique chemical properties and potential application value, and has attracted much attention in many fields of chemistry and related disciplines.
    What are the main uses of H-Imidazo [1,2-a] pyridine?
    H-imidazolo [1,2-a] pyridine, which is a class of nitrogen-containing heterocyclic organic compounds. It has a wide range of uses and has important applications in many fields.
    In the field of medicinal chemistry, its role is crucial. Many drug development uses H-imidazolo [1,2-a] pyridine as the key parent nucleus structure. Due to its unique structure, it can precisely bind to specific targets in organisms, thus exhibiting diverse biological activities. For example, some drugs developed on this basis have antibacterial effects and can effectively inhibit the growth and reproduction of bacteria, providing a powerful means to fight bacterial infections and diseases; others have anti-tumor activities, which can inhibit the proliferation and spread of tumor cells through specific mechanisms, bringing new hope for cancer treatment.
    In the field of materials science, H-imidazolo [1,2-a] pyridine also has outstanding performance. Due to its special electronic structure and chemical properties, it can be used to prepare functional materials with excellent performance. For example, in organic optoelectronic materials, introducing it into the molecular structure of materials can optimize the photoelectric properties of materials, so that materials can play a key role in devices such as Light Emitting Diodes and solar cells, and improve the luminous efficiency and energy conversion efficiency of devices.
    Furthermore, in the field of organic synthetic chemistry, H-imidazolo [1,2-a] pyridine is often used as an important intermediate. With its active chemical properties, it can participate in a variety of organic reactions. Through ingenious design and synthesis route planning, complex and diverse organic compounds can be constructed, greatly enriching the types of organic compounds, and injecting strong impetus into the development of organic synthetic chemistry.
    In short, H-imidazolo [1,2-a] pyridine plays an indispensable role in many fields such as drugs, materials, and organic synthesis, and is of great significance to promote the development of related fields.
    What are the synthesis methods of H-Imidazo [1,2-a] pyridine
    The synthesis of H-imidazolo [1,2-a] pyridine is a crucial research direction in the field of chemistry. After many studies, there are several common synthesis paths available for presentation.
    First, pyridine and aldehyde are used as starting materials, and after condensation reaction, the prototype of the product can be obtained. In this path, pyridine and aldehyde under specific reaction conditions, such as suitable temperature, pressure and the ingenious help of catalysts, the two blend and condensate to construct the basic structure of imidazolo [1,2-a] pyridine. In the meantime, the choice of catalyst is very critical. Different catalysts, such as certain metal salts or organic bases, will have a significant impact on the reaction rate and yield.
    Second, there are also those who use halogenated pyridine and nitrogen-containing heterocyclic compounds as starters. Through nucleophilic substitution, the chemical bonds between the two interact to gradually build the structure of the target product. In this process, the halogenated atom activity of halogenated pyridine and the structural characteristics of nitrogen-containing heterocyclic compounds are all important factors affecting the reaction process. Precise control of temperature and reaction time is also indispensable for obtaining the ideal product.
    Third, some synthesis methods also involve cyclization reactions. Using compounds with specific structures as raw materials, in a suitable reaction environment, intramolecular cyclization occurs to generate H-imidazolo [1,2-a] pyridine. In this approach, the structural design of the raw material molecule needs to be extremely delicate to ensure the smooth progress of the cyclization reaction. At the same time, the properties of the reaction solvent also play a role in the selectivity and yield of the reaction.
    All the above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to carefully select the most suitable synthesis path according to specific requirements, such as product purity, synthesis cost, ease of control of reaction conditions, etc., in order to achieve the synthesis of H-imidazolo [1,2-a] pyridine efficiently and with high quality.
    What are the physical properties of H-Imidazo [1,2-a] pyridine?
    H-imidazolo [1,2-a] pyridine is a class of organic compounds. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
    First of all, on its appearance, under normal conditions, H-imidazolo [1,2-a] pyridine is mostly white to light yellow crystalline powder. This color characteristic is quite useful for preliminary identification and determination of its purity. Looking at whether its color is uniform or not, and whether there are variegated colors, you can know its purity.
    As for the melting point, the melting point of H-imidazolo [1,2-a] pyridine is usually within a specific range. Accurate determination of the melting point can provide a key basis for the identification of this compound. Due to the different purity of the substance, the melting point may be slightly different. And the determination of the melting point can also help to determine the crystal structure, and the melting point may also change due to different crystal forms.
    In terms of solubility, H-imidazolo [1,2-a] pyridine exhibits a certain solubility in organic solvents such as ethanol and dichloromethane. This property makes it of great significance in the steps of reaction system construction, product separation and purification in organic synthesis. The dissolution, reaction and subsequent separation of the compound can be achieved by selecting a suitable solvent. In water, its solubility is relatively limited, which also limits its application in aqueous systems.
    In addition, the density of H-imidazolo [1,2-a] pyridine is also one of its physical properties. Although density data is not as concerned as melting point and solubility in general applications, in specific chemical processes, such as material transportation and precise control of mixing ratios, accurate knowledge of density is also indispensable to ensure the accuracy and stability of the process.
    What is the price range of H-Imidazo [1,2-a] pyridine in the market?
    The price of H-imidazolo [1,2-a] pyridine in the market often varies depending on quality, source, supply and demand. In the chemical market of Huaxia, if it is an ordinary purity, it is about hundreds of yuan per kilogram. If the purity exceeds 90%, the price may reach more than 1,000 yuan. However, in overseas markets, due to trade tariffs and logistics fees, the price may be higher.
    In the field of fine chemicals, the demand is increasing, and the price fluctuates accordingly. If you buy in bulk, you can negotiate with the supplier, or get a preferential price. And at different times, due to raw materials and production factors, the price also rises and falls. Therefore, if you want to know the exact price, you should consult the chemical raw material supplier and carefully observe the market situation to get an accurate quotation.