Ethylh Imidazo 1 2 A Pyridine 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

ethylH-imidazo[1,2-a]pyridine-2-carboxylate

    Specifications

    HS Code

    547323

    Chemical Formula C10H10N2O2
    Molar Mass 190.2 g/mol
    Appearance Solid (usually)
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Low solubility (organic compound)
    Solubility In Organic Solvents Soluble in common organic solvents
    Density Data needed
    Pka Data needed
    Flash Point Data needed

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of ethyl H-imidazo [1,2-a] pyridine-2-carboxylate
    The chemical structure corresponding to "ethyl + H - imidazo [1,2 - a] pyridine - 2 - carboxylate" is: This compound is called imidazo [1,2 - a] pyridine - 2 - carboxylate ethyl ester. In its structure, there is a parent nucleus structure of imidazo [1,2 - a] pyridine, which is formed by fusing an imidazole ring with a pyridine ring. Specifically, the nitrogen atom at the 1st position of the imidazole ring is connected to the carbon atom at the 2nd position of the pyridine ring, thus forming a unique fused ring system. A carboxyl ethyl ester substituent is connected at the 2nd position of the fused ring system, that is, -COOCH 2O CH. This chemical structure gives the compound specific physical and chemical properties, and shows potential application value in many fields such as organic synthesis and medicinal chemistry. Its unique structure can participate in a variety of chemical reactions, providing a foundation for the creation of new compounds.
    What are the main uses of ethyl H-imidazo [1,2-a] pyridine-2-carboxylate
    Ethyl + H - imidazo [1,2 - a] pyridine - 2 - carboxylate is ethyl - H - imidazolo [1,2 - a] pyridine - 2 - carboxylate, which is widely used. In the field of medicine, it can be used as a key intermediate to create drugs for the treatment of various diseases. Due to the unique chemical structure of this compound, it can interact with specific targets in organisms, or regulate physiological processes, or intervene in disease progression, so it is often favored by pharmaceutical chemists to develop new specific drugs.
    In the field of materials science, ethyl-H-imidazo [1,2-a] pyridine-2-carboxylate also has important uses. It can be introduced into polymer materials through specific chemical reactions to improve material properties, such as enhancing material stability, enhancing its mechanical strength or imparting special optical and electrical properties. In this way, the compound offers the possibility to develop new functional materials, with potential applications in many fields such as electronics and optics.
    In addition, in the field of organic synthesis, it is often used as an important building block. With its unique structure and reactivity, chemists can use it to carry out various organic reactions and build more complex organic molecular structures. This is of great significance for the synthesis of natural products and new organic functional molecules. It helps organic synthetic chemistry to continuously expand the boundaries and lay the foundation for the discovery of novel compounds and the exploration of their potential applications. In short, ethyl-H-imidazo [1,2-a] pyridine-2-carboxylate plays an important role in many fields such as medicine, materials, and organic synthesis, and promotes technological innovation and development in related fields.
    What are the synthetic methods of ethyl H-imidazo [1,2-a] pyridine-2-carboxylate
    The method of preparing ethyl + H - imidazo [1,2 - a] pyridine - 2 - carboxylate (ethyl - H - imidazo [1,2 - a] pyridine - 2 - carboxylate) often follows several paths.
    First, imidazo [1,2 - a] pyridine - 2 - carboxylic acid is used to start with imidazo [1,2 - a] pyridine - 2 - carboxylic acid, and it is esterified with ethanol under acid catalysis. Among them, concentrated sulfuric acid, p-toluenesulfonic acid, etc. can be used as catalysts. During the reaction, the two are co-placed in a reaction vessel in an appropriate ratio at a suitable temperature, or they need to be stirred to help them mix thoroughly. After the reaction is completed, the product is purified by distillation, extraction, column chromatography, etc.
    Second, starting from the corresponding halogenated pyridine and imidazole derivatives. First, the halogenated pyridine and imidazole derivatives undergo a nucleophilic substitution reaction in the presence of a base to construct the structure of imidazolo [1,2-a] pyridine. Then, the carboxyl group of the intermediate is esterified, interacted with ethanol and a catalyst to obtain the target product.
    Third, through a cyclization reaction. A chain compound with appropriate functional groups is used as the raw material, and under specific reagents and conditions, it undergoes intramolecular cyclization, and ethyl ester groups are introduced at the same time. This process may require precise regulation of reaction conditions, such as temperature, reaction time, reagent dosage, etc., to obtain a product with higher yield and purity.
    Each method has its own advantages and disadvantages. In actual synthesis, it should be selected according to factors such as the availability of raw materials, the difficulty of controlling reaction conditions, and the purity and yield of the product.
    What are the physical properties of ethyl H-imidazo [1,2-a] pyridine-2-carboxylate
    Ethyl + H - imidazo [1,2 - a] pyridine - 2 - carboxylate (ethyl - H - imidazo [1,2 - a] pyridine - 2 - carboxylate) is an organic compound with unique physical properties, which are described in detail by you.
    Looking at its properties, it is either a solid or a liquid under normal circumstances, which is related to the regularity of intermolecular forces and structures. If the molecules are arranged in an orderly manner and the force is strong, they tend to be solid; otherwise, they may be liquid.
    When it comes to melting point and boiling point, due to the heterocyclic structure of imidazolopyridine in the molecule and the ethyl ester group connected, the intermolecular forces are more complicated. The interactions between the heterocyclic ring and the ester group can form hydrogen bonds, van der Waals forces, etc., and the melting point, boiling point or higher. Because more energy is required to overcome these forces, the substance can be melted from solid to liquid, or vaporized from liquid to gaseous.
    In terms of solubility, the compound has both polar and non-polar parts. The nitrogen atom of the ester group and the heterocyclic ring has a certain polarity, so it may have a certain solubility in polar organic solvents such as ethanol and acetone, and can form hydrogen bonds or dipole-dipole interactions with solvent molecules. However, the molecule also contains non-polar parts composed of hydrocarbons, which may have certain solubility in non-polar solvents such as n-hexane. According to the principle of similar miscibility, the non-polar parts and non-polar solvent molecules can interact through van der Waals forces.
    Density is also an important physical property. Its molecular structure determines the density, and the relative molecular weight and the degree of intermolecular packing compactness are affected. Because it contains heterocyclic and ester groups, the structure may be compact, and the relative molecular weight may be larger, the density may be higher than that of common hydrocarbon solvents.
    The physical properties of this compound are of great significance for its synthesis, separation, purification and application. During synthesis, the appropriate reaction temperature and conditions need to be selected according to its melting point and boiling point; during separation and purification, solubility can assist in the selection of suitable solvents and separation methods; during application, such as for drug development or material preparation, physical properties determine whether it can meet specific needs.
    What is the market outlook for ethyl H-imidazo [1,2-a] pyridine-2-carboxylate?
    Ethyl H - imidazo [1,2 - a] pyridine - 2 - carboxylate is one of the organic compounds. In the field of chemical and pharmaceutical research and development, its market prospects are promising.
    Looking at the chemical industry, this compound is often used as a key intermediate in the synthesis of many complex organic molecules. Due to its unique molecular structure, it has the potential to participate in a variety of chemical reactions, so it can assist in the synthesis of materials with specific properties and functions. For example, in the creation of new polymer materials, it may be used to introduce specific functional groups to improve the physical and chemical properties of the material, such as improving the stability, flexibility or conductivity of the material. These new materials have the potential to be widely used in electronics, automotive and aerospace industries, so the demand for Ethyl H-imidazo [1,2-a] pyridine-2-carboxylate is expected to grow with the advancement of new materials.
    As for the field of medicine, its potential value is even more prominent. Numerous studies have shown that the structure of the compound is similar to that of some bioactive molecules, or it can exhibit unique pharmacological effects. It can be used as a lead compound, modified and optimized to develop innovative drugs for specific diseases. For example, in the development of anti-cancer drugs, by modifying its structure, it may be possible to develop drugs that can precisely act on cancer cell targets, improving the therapeutic effect and reducing side effects. In view of the increasing global demand for innovative drugs, Ethyl H-imidazo [1,2-a] pyridine-2-carboxylate has a promising market as a potential drug intermediate.
    However, it must also be faced with some challenges in its market development. The process of synthesizing this compound may have high complexity and high cost, which may limit its large-scale production and application. However, with the advancement of technology, the synthesis process is expected to be gradually optimized and the cost can be reduced. Overall, Ethyl H-imidazo [1,2-a] pyridine-2-carboxylate holds great potential for development in both the chemical and pharmaceutical fields, and the market prospect is quite bright.