Ethyl1 2 4 Difluorophenyl 7 Chloro 6 Fluoro 4 Oxohydropyridino 2 3 B Pyridine 3 C
pyridine pyrrole pyrazine piperidine piperazine

ethyl1-(2,4-difluorophenyl)-7-chloro-6-fluoro-4-oxohydropyridino[2,3-b]pyridine-3-c

    Specifications

    HS Code

    602078

    Chemical Name ethyl 1-(2,4-difluorophenyl)-7-chloro-6-fluoro-4-oxohydropyridino[2,3-b]pyridine-3-carboxylate
    Molecular Formula C16H10ClF3N2O3
    Molecular Weight 372.71
    Appearance Solid (Typical appearance description, actual may vary)
    Melting Point Needs experimental determination
    Boiling Point Needs experimental determination
    Solubility Solubility data in different solvents needs experimental determination
    Density Needs experimental determination
    Pka Needs experimental determination
    Logp Needs experimental determination

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    Frequently Asked Questions

    As a leading ethyl1-(2,4-difluorophenyl)-7-chloro-6-fluoro-4-oxohydropyridino[2,3-b]pyridine-3-c supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of ethyl1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxyhydropyrido [2,3-b] pyridine-3-c
    This is a structural problem of the chemical substance. The name of the substance is ethyl 1- (2,4-dichlorophenyl) -7-chloro-6-chloro-4-oxo-1,4-dihydroquinolino [2,3-b] quinoline-3-carboxylic acid. To understand its chemical structure, it can be analyzed step by step according to the naming rules. "Ethyl" indicates that this compound contains ethyl, which is a substituent attached to the host structure. "1- (2,4-dichlorophenyl) " means that there is a 2,4-dichlorophenyl group attached to the first position of the host structure, and the 2nd and 4th positions of this phenyl group are connected with monochlorine atoms. "7-chloro-6-chloro" shows that the 7th and 6th positions of the host structure are connected with chlorine atoms, respectively. " 4-Oxo-1,4-dihydro "indicates that the main structure is in the form of the 4-oxo group and the 1,4-dihydro group." Quinolino [2,3-b] quinoline "indicates that the main structure is formed by fusing two quinoline rings in the form of [2,3-b]." 3-carboxylic acid "indicates that there are carboxylic acid groups connected at the 3 position. In summary, the structure of this compound is obtained by connecting the above parts according to the naming convention.
    What are the main uses of ethyl1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxyhydropyrido [2,3-b] pyridine-3-c
    Ethyl 1- (2,4-difluorophenyl) -7-fluoro-6-fluoro-4-oxo-1,4-dihydroquinolino [2,3-b] quinoline-3-carboxylic acid, which is widely used. In the field of medicine, it is often used as a key component of antibacterial drugs. It can effectively inhibit the key metabolic process or biosynthetic pathway of bacteria by virtue of its unique chemical structure, hinder the growth and reproduction of bacteria, and has significant effect on a variety of bacterial infectious diseases, such as respiratory tract and urinary tract infections. In the field of scientific research, it is an important chemical tool that helps scientists to deeply explore the chemical properties, biological activities and mechanisms of quinoline and quinoline compounds, and helps to develop more effective and highly selective new drugs or biologically active substances. In the field of materials science, perhaps due to its special optical and electrical properties, it can be used to develop new organic materials, such as optoelectronic materials, which offer possibilities for the innovative development of materials science.
    What is the preparation method of ethyl1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxyhydropyrido [2,3-b] pyridine-3-c
    The preparation of ethyl 1- (2,4-dichlorophenyl) -7-chloro-6-fluoro-4-oxo-chromando [2,3-b] pyridine-3-carboxylate requires several steps. In the first step, 2,4-dichlorobenzaldehyde and diethyl malonate are taken, and the condensation of Knoevenagel is carried out under the catalysis of sodium alcohol to obtain the corresponding cinnamate derivative.
    In the second step, the derivative is combined with 6-fluoro-7-chloro-4-hydroxychromando-2-one in a suitable solvent, such as DMF, and catalyzed by base to cause nucleophilic substitution of the two. The alkali can be selected from potassium carbonate, etc., and heated to a suitable temperature. When the reaction number is counted, this step aims to introduce the chromanone structure to build a key skeleton.
    Thereafter, the obtained intermediate is hydrolyzed under acidic or alkaline conditions. Depending on the reagent used, the reaction conditions are controlled to convert the ester group into carboxylic acid. If hydrolyzed with acid, dilute hydrochloric acid can be selected; if a base, such as sodium hydroxide solution, is hydrolyzed and then re-acidified.
    Finally, the carboxylic acid and ethanol are esterified under the catalysis of concentrated sulfuric acid. When the reflux number is reached, the target product ethyl 1- (2,4-dichlorophenyl) -7-chloro-6-fluoro-4-oxo [2,3-b] pyridine-3-carboxylic acid ester can be obtained. After each step of the reaction, separation and purification operations, such as extraction and column chromatography, are required to ensure the purity of the product and obtain high-quality target products.
    What are the physicochemical properties of ethyl1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxyhydropyrido [2,3-b] pyridine-3-c
    Ethyl 1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxo-4H-chromoeno [2,3-b] pyridine-3-carboxylic acid, this is an organic compound.
    Looking at its physical and chemical properties, it is mostly in solid form at room temperature. Because the molecule is rich in polar groups, such as carboxyl groups, it shows some solubility in some polar solvents, such as ethanol and acetone; however, in non-polar solvents, such as n-hexane, the solubility is poor. The determination of its melting point is of great significance for the determination of purity. After experimental determination, the melting point is in a specific temperature range.
    In terms of chemical properties, the carboxyl group has a high activity and can be neutralized with bases to form corresponding carboxylic salts. For example, when reacted with sodium hydroxide, ethyl 1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxo-4H-chromopheno [2,3-b] pyridine-3-carboxylate sodium salt will be formed. At the same time, the chlorine atom in the compound molecule can participate in the substitution reaction under appropriate conditions and can be replaced by other nucleophiles, thereby deriving new compounds with diverse structures, providing rich possibilities for the field of organic synthesis.
    What are the market prospects for ethyl1- (2,4-difluorophenyl) -7-chloro-6-fluoro-4-oxyhydropyrido [2,3-b] pyridine-3-c?
    Look at what you said "ethyl1- (2,4-difluorophenyl) -7-fluoro-6-fluoro-4-oxo-pyridino [2,3-b] pyridine-3-carboxylate ethyl ester", which is an organic compound. In terms of market prospects, many factors need to be looked at.
    First, depending on its application. If it is used in the field of medicine, there is a great demand for new compounds in pharmaceutical research and development today. If this compound has unique pharmacological activity, it can be used as a drug lead compound for the development of anti-disease drugs, such as anti-cancer, antiviral and other drugs, and the prospect is good. Because the pharmaceutical market is huge, there is a constant demand for innovative drugs. Once the research and development is successful, it can be rewarded handsomely.
    Second, consider the difficulty and cost of synthesis. If the synthesis steps are complicated, expensive raw materials or harsh conditions are required, large-scale production is limited, and the cost is also high, it may be at a disadvantage in market competition. However, if the synthesis process is simple and the cost is controllable, it is conducive to large-scale production and marketing activities.
    Third, observe the market competition situation. If compounds with similar structures and functions have flooded the market and have mature applications, this compound needs to have unique advantages, such as higher activity and lower toxicity.
    Fourth, the impact of policies and regulations should not be underestimated. The pharmaceutical, chemical and other industries are subject to strict regulations, and the research and development, production and sales of compounds must meet corresponding standards. If policies are favorable for innovative compounds, this compound may gain more development opportunities; conversely, strict regulations may increase its difficulty in entering the market.
    Overall, the market prospect of this compound cannot be determined. It is necessary to comprehensively consider factors such as use, synthesis, competition and regulations to know its rise and fall in the market.