Ethyl imidazo[1,2-a]pyridine-2-carboxylate

Ethyl imidazo [1,2-a] pyridine-2-carboxylate is also a compound. Its molecule is composed of imidazole-pyridine-based carboxyethyl ester.
The core of this compound is imidazole-pyridine, which is the five-element of the nitrogen atom, and is aromatic. Pyridine also contains nitrogen six-element, and the two fuse to form the imidazole-pyridine-based system, which makes the whole molecule have a specific molecular composition.
In the second position of the system, there is a carboxylethyl ester group, that is, -COOCH ² CH. Among them, the carbonyl group (-C = O) has high inverse activity, such as nuclear addition and other inverse properties. The solubility and space resistance of ethoxy (-OCH ² CH) of ethyl ester groups are affected.
For example, Ethyl imidazo [1,2 - a] pyridine - 2 - carboxylate is cleverly connected to imidazole-pyridine-based carboxyethyl ester groups, which gives specific physical properties of compounds. It may be important for the synthesis and physicochemical fields.

Ethyl imidazo [1,2 - a] pyridine - 2 - carboxylate, that is, imidazo [1,2 - a] pyridine - 2 - carboxylate, is widely used. In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it endows molecules with specific biological activities and pharmacological properties. By modifying and modifying its structure, drugs with diverse therapeutic effects can be developed, such as antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the field of materials science, or can participate in the preparation of functional materials. Due to the reactivity of its structure, it can react with other compounds to build materials with special properties, such as optical materials, electrical materials, etc., which may have extraordinary applications in the field of optoelectronics.
In the field of organic synthesis, this compound, as an important intermediate, can be derived from a variety of organic reactions to generate more complex and diverse organic compounds, providing rich raw materials and pathways for the development of organic synthetic chemistry, helping scientists explore the synthesis methods and strategies of new organic compounds, and promoting the progress of organic synthetic chemistry.

Ethyl imidazo [1,2 - a] pyridine - 2 - carboxylate, there are various synthesis methods. One common one is to react with appropriate halogenated alkanes in an alkaline environment to form an intermediate, and then cyclize to obtain this compound. The reaction process begins with pyridine as the starting material. The halogen atom of the halogenated alkane is electrophilic. In an alkaline medium, the lone pair electron of the pyridine nitrogen atom attacks the carbon atom of the halogenated alkane and forms a carbon-nitrogen bond to obtain an intermediate. Subsequently, the intermediate is cycled in the molecule under specific conditions to form an imidazolopyridine structure, and then the carboxyl group is esterified with ethanol through an esterification reaction to obtain Ethyl imidazo [1,2-a] pyridine-2-carboxylate.
There is also another method, which uses nitrogen-containing heterocyclic compounds and carboxylic acid derivatives as raw materials, and is prepared by a series of reactions such as condensation and cyclization. First, the nitrogen-containing heterocyclic ring and carboxylic acid derivative are condensed under the action of a condensing agent, and then the cyclization is promoted under suitable conditions to construct an imidazolopyridine skeleton, and finally the ethyl ester group is introduced to complete the synthesis.
There is also a way to use transition metal catalysis. With suitable metal catalysts, such as palladium, copper, etc., catalyze the reaction between substrate molecules, promote the formation of carbon-carbon bonds and carbon-nitrogen bonds, and then ingeniously design the reaction steps to gradually build the structure of the target molecule, and finally obtain Ethyl imidazo [1,2-a] pyridine-2-carboxylate. These various synthesis methods have their own strengths, and they can be used according to actual needs and conditions.

Ethyl imidazo [1,2-a] pyridine-2-carboxylate is an organic compound with unique physical properties, with the following characteristics:
Appearance morphology, often in a crystalline solid state, stable at room temperature and pressure, this morphology is easy to store and operate. The crystal structure is regular and orderly, giving it specific physical properties.
Melting point Boiling point, the melting point is about [specific value], at this temperature, the intermolecular force changes, and the solid state converts to a liquid state. The boiling point varies according to the ambient pressure. Under standard conditions, the boiling point reaches [specific value]. This property is extremely critical when separating and purifying the compound. It can be separated according to the difference in boiling point by means of distillation and other means. In terms of solubility,
exhibits good solubility in organic solvents such as ethanol and dichloromethane. This is because the molecular structure of the compound has a similar polarity to that of organic solvents, and it is easily soluble in such solvents according to the principle of "similar miscibility". However, the solubility in water is poor because of the large difference in molecular polarity from water. This difference in solubility is of great significance in the extraction, purification and choice of reaction system of the compound.
The density is moderate, about [specific value] g/cm ³, which is similar to the density of common organic solvents. When it comes to mixing solution operations, it has a significant impact on phase separation and material distribution.
has good stability and can maintain the chemical structure unchanged for a long time under normal conditions. However, under extreme conditions such as strong acids, strong bases or high temperatures, its structure may change and initiate chemical reactions. These physical properties of
Ethyl imidazo [1,2-a] pyridine-2-carboxylate are widely used in organic synthesis and medicinal chemistry, and are extremely important for understanding its chemical reactivity and practical applications.

Ethyl imidazo [1,2 - a] pyridine - 2 - carboxylate is also an organic compound. However, it is difficult to determine the price in the market. The price is determined by many factors.
First, the price of raw materials has a great impact. If the starting materials required to synthesize this compound are scarce or expensive, the price of the finished product will also rise. Second, the preparation process is also key. Complex processes that require high-end technology and equipment will increase production costs and thus increase selling prices. Third, market supply and demand conditions also affect its price. If there are many people who want it, and there are few people who supply it, the price will rise; on the contrary, if the supply exceeds the demand, the price will fall.
Looking at the past market, the price of chemical products often fluctuates with many external factors. For example, changes in economic conditions, policies and regulations can make prices fluctuate. In addition, the prices produced by different manufacturers will vary depending on quality and purity. Therefore, if you want to know the exact market price of Ethyl imidazo [1,2 - a] pyridine - 2 - carboxylate, you need to check the current chemical product trading platform, consult relevant dealers, or refer to recent market survey reports to get a more accurate number.