Ethyl 8 Benzyloxy 2 Methylh Imidazo 1 2 A Pyridine 3 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl 8-(benzyloxy)-2-methylH-imidazo[1,2-a]pyridine-3-carboxylate

    Specifications

    HS Code

    408880

    Chemical Formula C20H20N2O4
    Molar Mass 352.384 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Melting Point Specific value would need experimental determination
    Boiling Point Estimated to be high due to its molecular structure
    Density Needs experimental measurement
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Odor Likely odorless or with a faint organic odor

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    Frequently Asked Questions

    As a leading Ethyl 8-(benzyloxy)-2-methylH-imidazo[1,2-a]pyridine-3-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate
    Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate is an organic compound. This compound has important uses in many fields.
    In the field of medicinal chemistry, it is often a key intermediate. Because the compound has a specific chemical structure and activity, it can be used as a starting material through a series of exquisite chemical reactions to construct drug molecules with more complex and diverse structures. By modifying and modifying its structure, the resulting drug molecule can be endowed with unique pharmacological activities, such as the ability to bind to specific targets, thus laying the foundation for the development of new drugs and helping to develop innovative drugs with better efficacy and fewer side effects.
    In the field of materials science, such compounds can be used to prepare materials with special properties. Its structural properties may endow materials with unique optical, electrical or thermal properties. For example, introducing it into polymer material systems can improve the film formation and stability of materials, or even give materials responsiveness to specific substances, making materials show potential application value in sensors, optoelectronic devices, etc.
    Furthermore, in organic synthetic chemistry, it is an important cornerstone for the synthesis of other complex organic molecules. Chemists use its unique structure and various organic synthesis methods to build complex carbon skeletons and functional groups as a starting point, expand the structural diversity of organic compounds, and provide strong support for the development of organic chemistry theory and practice.
    What are the synthesis methods of Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate
    Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate is an organic compound, and its synthesis methods are various. The following are common methods:
    The starting material selects a pyridine or imidazole compound with a specific substituent. One method is to first react the pyridine derivative containing a suitable substituent with the imidazole derivative under suitable conditions. This reaction often requires the help of specific catalysts, such as some metal salt catalysts, to promote the effective binding of the two parts to form the basic structure of imidazolopyridine.
    After the core structure is constructed, benzyloxy and ethyl ester groups are introduced. When benzyloxy is introduced, a reagent containing benzyloxy groups can be used to react with the obtained intermediates under alkali catalysis conditions. The choice of base is crucial, such as potassium carbonate, which is used to promote the smooth progress of the reaction, so that the benzyloxy group can precisely replace the hydrogen atom at the target position.
    The introduction of ethyl ester groups is often achieved by esterification with the corresponding carboxylic acid as the raw material. Generally, ethanol and suitable dehydrating agents, such as dicyclohexyl carbodiimide (DCC), are used. Under mild heating conditions, carboxylic acids and ethanol are esterified, and ethyl ester groups are successfully introduced into the target molecule.
    The reaction process needs to be monitored by a variety of analytical methods, such as thin layer chromatography (TLC), which can understand the degree of reaction progress in real time, and know the consumption of raw materials and product formation. After the reaction is completed, the product is separated and purified by extraction, column chromatography, etc., to obtain high-purity Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate. In this way, after careful operation in multiple steps, the target product can be obtained.
    What are the physical properties of Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate
    Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate is an organic compound. Its physical properties are important for its performance in various chemical processes and applications.
    The appearance of this compound is often white to pale yellow crystalline powder. This morphology makes it easy to handle and store in the solid state, and its crystalline structure also affects its stability. Its melting point is a key physical property. Generally speaking, the melting point can reflect the strength of intermolecular forces. Higher melting points suggest strong intermolecular forces. It may be due to the interaction of hydrogen bonds, van der Waals forces, etc., resulting in a tight arrangement of molecules. It requires more energy to disintegrate its lattice and transform it into a liquid state.
    Solubility is also a key property. In organic solvents, such as common ethanol, dichloromethane, etc., it may exhibit some solubility. This is because the molecular structure of the compound contains functional groups that can interact with organic solvent molecules, such as dipole-dipole interaction, dispersion force, etc., to help it disperse in the solvent. However, in water, its solubility may be poor, because the hydrophobic part of the molecule, such as benzene ring, will reduce the ability to form hydrogen bonds and other interactions with water molecules.
    In addition, the density of the compound is also significant. The density reflects the mass of the substance per unit volume. When it comes to mixing, separation, etc., the density data can assist in predicting its distribution in the system. Knowing its density is conducive to designing relevant chemical operation procedures to achieve the purpose of efficient separation or mixing. The physical properties of Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate, from appearance, melting point, solubility to density, play a key role in its research and application in the field of chemistry, laying the foundation for further exploration of its chemical properties and practical uses.
    What are the chemical properties of Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate
    Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate is an organic compound. Its chemical properties are rich and diverse, let me tell you one by one.
    In terms of physical properties, it is usually a solid state. Due to the existence of various forces between molecules, such as van der Waals forces and hydrogen bonds, the molecules are arranged in an orderly manner and solidified. Its melting point and boiling point depend on the characteristics of the molecular structure. Structural units such as benzene ring, pyridine ring and ester group in the molecule enhance the intermolecular forces, and then the melting point and boiling point are relatively high.
    In terms of chemical properties, ester group is an important active site of this compound. It can undergo hydrolysis reaction. Under acidic or basic conditions, the carbonyl carbon of the ester group is attacked by nucleophiles, thereby breaking the ester bond. In acidic media, hydrolysis generates corresponding carboxylic acids and alcohols; in alkaline media, hydrolysis is more thorough, forming carboxylic salts and alcohols. This is the principle of saponification reaction.
    The benzoxy part of the molecule has a certain electron cloud density and can undergo electrophilic substitution. For example, under the action of an appropriate catalyst, it can undergo halogenation reaction with halogenated reagents to introduce halogen atoms on the benzene ring; it can also undergo nitrification reaction with mixed acids such as nitric acid and sulfuric acid to introduce nitro groups.
    In addition, the structure of imidazolopyridine gives the compound unique chemical activity. The nitrogen atom in this structure has a lone pair of electrons and can participate in the coordination reaction as an electron donor to form complexes with metal ions. This property may have potential applications in the field of materials science and catalysis. It may also participate in some unique reactions of heterocyclic compounds, such as electrophilic substitution on the ring with electrophilic reagents, which makes the reaction check point selective due to the electronic effect of nitrogen atoms.
    The chemical properties of this compound are determined by its specific structural units, which lay the foundation for its application in many fields such as organic synthesis and pharmaceutical chemistry.
    Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate What is the price range in the market?
    I don't know if "Ethyl 8- (benzyloxy) -2-methylH-imidazo [1,2-a] pyridine-3-carboxylate" is in the market price range. This is a fine chemical, and its price is affected by many factors.
    First, the purity has a great impact. If the purity is very high, it is almost used for high purity level of scientific research, and there are few impurities, the price must be high; if it is used in industry with lower purity and contains certain impurities, the price is relatively low.
    Second, the production scale also plays a role. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price may be more affordable; in small-scale production, the cost is higher, and the price will rise accordingly.
    Third, the market supply and demand situation is critical. If the market demand for this product is strong and the supply is limited, if the demand for a specific industry increases sharply, or the supply is reduced due to production difficulties, the price will often go up; on the contrary, if the demand is low and the supply is sufficient, the price will fall.
    Fourth, the cost of raw materials is also an important factor. The price fluctuation of raw materials required to prepare this product directly affects its production cost, which in turn affects the selling price.
    Because I don't know the specific situation of the current market, I can't tell the price range exactly. If you want to know the details, you can consult chemical product suppliers, relevant trading platforms, or research chemical market market market reports to get a more accurate price range.