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What is the chemical structure of ethyl 6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate?
Alas! This "ethyl 6 - iodoH - imidazo [1,2 - a] pyridine - 2 - carboxylate" is also known as the compound. To clarify its chemical properties, let me tell you.
In this compound, "ethyl" and ethyl, that is, -C ² H, are often found in compounds with esters, and the carboxyl group is in the ester phase. "6 - iodo" indicates that there is an iodine atom substituted at the position of the specific system 6. The iodine atom, the element is also the element, the sexual activity, and the physical and chemical properties of the compound are affected.
"Imidazo [1,2-a] pyridine" is a fused carboxylate system, formed by fusing imidazole and pyridine. Imidazole has a nitrogen atom, and pyridine also contains a nitrogen atom. The two fuse to form a special sub-cloud, which gives the compound special chemical activity.
"2-carboxylate" shows that there is a carboxylate-derived ester moiety at the position of the fused system. This ester moiety is ethyl phase, forming a complete ester.
Therefore, the chemical composition of this compound is composed of an imidazolopyridine fused system substituted by ethyl and iodine atoms and a 2-position carboxylic acid ethyl ester group. The interaction of each part determines the physical properties of the compound, which may be of great significance in the fields of synthesis, physicochemistry, etc.
What are the main uses of ethyl 6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate
Ethyl-6-iodine-H-imidazolo [1,2-a] pyridine-2-carboxylic acid ester has a wide range of uses and has its own impact in many fields.
In the field of pharmaceutical chemistry, it is often a key intermediate in organic synthesis. Through delicate chemical reactions, it can be converted into active pharmaceutical ingredients with more complex structures and specific functions. Taking the development of new antibacterial drugs as an example, based on the unique structure of this compound, through modification and modification, the new compound can be endowed with stronger antibacterial ability and targeting of specific pathogens, improving drug efficacy and reducing damage to human normal cells. < Br >
In the field of materials science, there are also potential uses. Due to its structural properties, it may be involved in the preparation of functional materials with special optical and electrical properties. For example, by compounding with specific polymers, materials that can efficiently emit light or have unique electrical conductivity in optoelectronic devices can be prepared for the manufacture of advanced optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells, helping to improve the performance and efficiency of these devices. In the process of scientific research and exploration, as an important model compound for studying the relationship between molecular structure and activity, scientists can gain insight into how the structural changes of imidazolopyridine compounds affect biological activity and physicochemical properties, thus providing a solid theoretical basis and direction for the design and development of better performance compounds, and promoting the vigorous development of organic chemistry, medicinal chemistry and other disciplines.
What is the synthesis method of ethyl 6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate
The method of synthesizing ethyl 6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate (6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate) has been explored by many scholars in the past. One of the common methods is to use an appropriate pyridine derivative as the starting material. First, the pyridine derivative is co-located with iodine-containing reagents, such as iodine elemental (I ²) or potassium iodide (KI), under specific reaction conditions. This reaction may need to be carried out in a suitable organic solvent, such as dichloromethane, N, N-dimethylformamide (DMF), or a catalyst, such as copper salts (such as cuprous iodide CuI), etc., by means of its catalytic power, the iodine atom can smoothly replace the hydrogen atom at a specific position in the pyridine ring to obtain the 6-iodopyridine derivative.
Subsequently, the 6-iodopyridine derivative is reacted with the reagent containing the carboxyl-ethyl ester structure. The reagent containing the carboxyl-ethyl ester structure can be activated with a base first, such as potassium carbonate (K _ 2O _ CO), sodium hydroxide (NaOH) and other bases, to generate the corresponding active intermediate in the organic solvent. Then this active intermediate is mixed with 6-iodopyridine derivatives, and the reaction temperature, time and other conditions are controlled to make the two undergo nucleophilic substitution or other suitable reactions, then 6-iodopyridine-H-imidazolo [1,2-a] pyridine-2-carboxylate ethyl ester.
Another way is to construct the parent nucleus structure of imidazolo [1,2-a] pyridine first, and then introduce iodine atom and carboxylethyl ester group on the parent nucleus. When constructing the parent nucleus, the structure of imidazolo [1,2-a] pyridine is gradually built with nitrogen-containing heterocyclic compounds and appropriate electrophilic or nucleophilic reagents according to specific reaction mechanisms, such as cyclization reaction. After the parent nucleus is formed, iodine atom and carboxyl ethyl ester are introduced separately as mentioned above to achieve the purpose of synthesis. However, each method has its own advantages and disadvantages. In actual operation, it is necessary to weigh the difficulty of reaction conditions, the availability of raw materials, the purity and yield of the product, and choose the best one.
What are the physical properties of ethyl 6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate
Ethyl-6-iodine-H-imidazolo [1,2-a] pyridine-2-carboxylic acid ester is one of the organic compounds. Its physical properties are particularly important, related to its use and characteristics.
Looking at its properties, at room temperature, this compound is mostly in a solid state, with a fine texture. Its color may be white or nearly white, just like the first snow in winter, pure and simple. Its melting point is also one of the key physical properties. It has been determined by many researchers and is about a specific temperature range. This temperature makes the forces between molecules reach equilibrium, causing the solid state to melt into a liquid state, like ice disappearing in the warm sun in spring.
When it comes to solubility, this compound behaves differently in organic solvents. In some polar organic solvents, such as ethanol and acetone, it is quite soluble, just like salt dissolves in water, and it is seamless; in non-polar solvents, such as n-hexane, the solubility is poor, just like oil floats in water, and it is distinct. This difference in solubility is due to the difference in the structure of the compound itself and the interaction between solvent molecules.
In addition, its density is also considerable. Compared with common solvents and substances, it has its own unique value, which reflects the close degree of molecular accumulation and is also related to other physical properties.
In addition, its volatility is relatively weak at room temperature and pressure, and it is not easy to escape into the air. It is like a stable person and does not easily show signs. This property makes it highly stable during storage and use, and can be stored for a long time without the worry of deterioration.
In summary, the physical properties of ethyl-6-iodine-H-imidazolo [1,2-a] pyridine-2-carboxylate, such as properties, melting point, solubility, density and volatility, have their own characteristics and are intertwined, which together outline the physical properties of this compound, laying a solid foundation for its application and research in the field of chemistry.
What is the market outlook for ethyl 6-iodoH-imidazo [1,2-a] pyridine-2-carboxylate?
Ethyl 6 - iodoH - imidazo [1,2 - a] pyridine - 2 - carboxylate is an organic compound. Looking at its market prospects, it can be discussed from multiple angles.
In the field of pharmaceutical research and development, organic heterocyclic compounds often have unique biological activities. This compound contains imidazolopyridine structure, or can exhibit a variety of pharmacological properties. For example, many innovative drug research and development focus on molecules with such structural units, hoping to discover new therapeutic drugs for the fight against tumors, inflammation, nervous system diseases, etc. If ethyl 6 - iodoH - imidazo [1,2 - a] pyridine - 2 - carboxylate is confirmed to have exact biological activity by research, pharmaceutical companies may be interested in it and invest resources to develop related drugs. The market prospect cannot be underestimated.
In the field of materials science, compounds containing iodine and specific heterocyclic structures may emerge in the field of optoelectronic materials. With the advance of science and technology, the demand for organic optoelectronic materials is increasing, such as organic Light Emitting Diode (OLED), organic solar cells, etc. If this compound is properly modified and applied to exhibit excellent optoelectronic properties, such as high carrier mobility and good luminous efficiency, a new market will be opened up for material manufacturers to compete.
Furthermore, from the perspective of chemical synthesis, this compound can be used as a key intermediate. Organic synthetic chemistry is constantly pursuing novel and efficient synthesis paths, and its unique structure may provide organic chemists with new synthesis ideas and challenges. If its synthesis process can be optimized and the cost is reduced, it will attract more chemical synthesis laboratories and chemical companies to participate, drive the development of its upstream and downstream products, and expand the market scale.
However, its market prospects also face challenges. The research and development process requires huge funds and a long time to confirm its biological activity or material properties. And the market competition is fierce. If other similar structural compounds occupy the market first, ethyl 6 - iodoH - imidazo [1, 2 - a] pyridine - 2 - carboxylate will be difficult to stand out. But overall, if its characteristics and applications can be fully exploited, ethyl 6 - iodoH - imidazo [1, 2 - a] pyridine - 2 - carboxylate may bloom in the fields of chemicals, medicine, materials and other fields, and reap considerable market returns.