Ethyl 6 Chloro 2 Pyridinecarboxylate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl 6-Chloro-2-Pyridinecarboxylate

    Specifications

    HS Code

    123946

    Chemical Formula C8H8ClNO2
    Molar Mass 185.61 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point Approx. 235 - 237 °C
    Density 1.24 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Flash Point Approx. 101 °C
    Odor Characteristic odor

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    General Information
    Where to Buy Ethyl 6-Chloro-2-Pyridinecarboxylate in China?
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    Frequently Asked Questions

    As a leading Ethyl 6-Chloro-2-Pyridinecarboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Ethyl 6-Chloro-2-Pyridinecarboxylate?
    Ethyl 6 - Chloro - 2 - Pyridinecarboxylate, which is ethyl 6 - chloro - 2 - pyridinecarboxylate, is widely used. In the field of medicine, it is often a key synthesis intermediate. Many drugs are created with it as a starting material, and through a series of delicate chemical reactions, compounds with specific pharmacological activities are derived. For example, some therapeutic drugs for specific diseases, in their complex synthesis path, 6 - chloro - 2 - ethyl pyridinecarboxylate is introduced as an important structural fragment, which plays a decisive role in the overall activity and efficacy of drug molecules.
    In the field of pesticides, it also plays an important role. It can be used to prepare high-efficiency, low-toxicity and environmentally friendly pesticide products. With its unique chemical structure, it can be combined with specific biological targets in pests to interfere with the normal physiological metabolism of pests, thus achieving excellent insecticidal and insect repellent effects. At the same time, because of its relatively stable chemical properties, it is not easy to decompose rapidly in the environment, and can maintain a certain period of efficacy, providing a strong guarantee for the prevention and control of crops.
    In organic synthetic chemistry research, 6-chloro-2-pyridinecarboxylate ethyl ester is a popular basic raw material. Chemists use their special functional group properties to construct organic compounds with diverse structures and functions through various classical organic reactions, such as substitution reactions and addition reactions. These compounds not only enrich the material library of organic chemistry, but also lay the material foundation for research in new materials, catalysts and other fields, and promote continuous progress and innovation in related fields.
    What are the physical properties of Ethyl 6-Chloro-2-Pyridinecarboxylate?
    Ethyl 6 - Chloro - 2 - Pyridinecarboxylate, Chinese name 6 - chloro - 2 - ethyl pyridinecarboxylate, is an organic compound. Its physical properties are as follows:
    Viewed, this substance is often a colorless to light yellow transparent liquid, which shines brightly in the sun, as if it contains light. Its smell is unique, with a faint irritating smell, but it is not pungent and intolerable, and it can be felt when it is close to the smell.
    When it comes to the melting point, the melting point is quite low, and it is a liquid at room temperature. The boiling point varies according to the external pressure. Under normal circumstances, it boils at a specific temperature range, which guarantees that it will be converted into a gaseous state when heated moderately.
    Solubility is also an important physical property. It is insoluble in water, and the two seem to be distinct and incompatible with each other. However, in organic solvents, such as ethanol, ether, dichloromethane, etc., it can be mutually soluble in any ratio, just like water emulsion, showing good solubility. This property makes it widely used in many fields such as organic synthesis.
    In terms of density, compared with water, its density is slightly higher. After mixing it with water and letting it stand, it will sink to the bottom of the water, and the stratification is clearly visible.
    Ethyl 6 - Chloro - 2 - Pyridinecarboxylate's physical properties have attracted much attention in the chemical, pharmaceutical and other industries, providing an important material basis for the development of related fields.
    What is the chemical synthesis method of Ethyl 6-Chloro-2-Pyridinecarboxylate?
    The method of preparing ethyl 6-chloro-2-pyridinecarboxylate is not detailed in the ancient book "Tiangong Kaiwu", but according to the principle of chemical synthesis today, its path can be found.
    First, 2-pyridinecarboxylic acid is used as the starting material. First, 2-pyridinecarboxylic acid and ethanol are esterified under the action of a catalyst such as sulfuric acid. This process needs to be controlled at a moderate temperature, usually under the condition of heating and reflux, so that the two can fully react. The catalytic force of sulfuric acid can promote the reaction to the direction of ester formation. After a few years, when the reaction reaches equilibrium, a crude product of 6-chloro-2-pyridinecarboxylate can be obtained. After distillation, extraction, recrystallization and other purification methods, a pure product can be obtained.
    Second, 6-chloro-2-pyridyl formyl chloride can also be used as a raw material. When it reacts with ethanol, the reaction is relatively rapid and often needs to be carried out at low temperature and in the presence of an acid binding agent. The acid binding agent can remove the hydrogen chloride generated by the reaction and promote the smooth reaction. After the reaction is completed, the same separation and purification steps, such as vacuum distillation, can remove the unreacted raw materials and by-products to obtain a high-purity 6-chloro-2-pyridyl carboxylate ethyl ester. During the preparation of
    , the purity of the raw materials and the reaction conditions, such as temperature, amount of catalyst, reaction time, etc., all have a crucial impact on the yield and purity of the product. Fine control is required to achieve the desired result.
    What are the precautions for Ethyl 6-Chloro-2-Pyridinecarboxylate during storage and transportation?
    Ethyl 6-chloro-2-pyridinecarboxylate is an organic compound. When storing and transporting, many matters must be paid attention to.
    Let's talk about storage first. First, you must choose a cool, dry and well-ventilated place. This is because the material is heated or in a humid environment, it may cause chemical reactions and damage the quality. For example, if it is placed in a hot warehouse in summer, it may cause decomposition. Second, it must be stored in isolation from oxidants, acids, bases, etc. Due to its active chemical properties, contact with their substances or violent reactions can cause dangerous accidents. Third, the storage container must be well sealed. If the seal is not good, the material will evaporate, not only causing material loss, but also volatile gas or harmful to health and pollution of the environment.
    As for transportation, there is also attention to it. The transport vehicle is selected to ensure that the carriage is dry and clean, and there are no residual other chemicals to react with it. During transportation, it is necessary to protect against sun exposure and rain. If driving in summer, shading and rain protection measures are required. The loading and unloading process must be light and light to avoid material leakage caused by damage to the container. If there is a leak, it should be dealt with according to the emergency plan immediately, evacuate personnel, isolate the scene, and contain the leak with suitable materials.
    In conclusion, the storage and transportation of ethyl 6-chloro-2-pyridinecarboxylate must be handled in strict accordance with regulations and with caution to ensure safety and avoid accidents.
    What is the market price range for Ethyl 6-Chloro-2-Pyridinecarboxylate?
    What I am asking you is the market price range of "Ethyl 6 - Chloro - 2 - Pyridinecarboxylate". The Chinese name of this substance may be ethyl 6 - chloro - 2 - pyridinecarboxylate. However, its market price range is difficult to describe in a single word.
    Because of the price, it is often affected by many factors. First, the state of market supply and demand is important. If the demand for this substance is strong and the supply is limited, the price will inevitably increase; conversely, if the supply exceeds the demand, the price will drop. Second, the cost of production also has a significant impact. The price of raw materials, the simplicity of production processes, and the amount of energy consumption are all related to the cost, which in turn is related to the selling price. Third, the quality is also related to the price. High quality, the price or excellent.
    In the past market, the price of such chemicals fluctuated indefinitely. In the past, the price range may vary depending on the purity, packaging, and purchase quantity. Small purchases, those with ordinary purity, the price per gram may be around tens of yuan to hundreds of yuan; if a large number of purchases are made, and the purity is high, the batch reaches the kilogram level, and the price per kilogram may range from several thousand yuan to ten thousand yuan. However, this is only a guess. The current market is unpredictable. To know the exact number, you need to consult the chemical raw material supplier in detail, or check it carefully on the chemical trading platform before you can get a near-real price range.