ethyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate

Ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid ester, this is an organic compound. Its chemical properties are unique, let me tell you one by one.
First of all, its physical properties are mostly solid at room temperature, due to the force between molecules. Its melting point and boiling point are closely related to the molecular structure. The molecule contains chlorine atoms, pyridine rings and pyrrole rings, and is connected by ester groups. Chlorine atoms have certain electronegativity, which can affect the polarity of molecules, causing them to exhibit unique solubility in some organic solvents. The existence of ester groups makes them have a certain solubility in organic solvents such as ethanol and acetone. However, the solubility in water is not good, and it is difficult to form strong interactions between ester groups and water molecules.
Chemical properties. The characteristics of ester groups cannot be ignored, and they can be hydrolyzed in case of acids or bases. In acidic media, the hydrolysis process is that protons first combine with the carbonyl oxygen of the ester group to enhance the positive electricity of carbonyl carbons, and water molecules attack carbonyl carbons. After a series of changes, carboxylic acids and alcohols are finally obtained. Under alkaline conditions, hydroxide ions directly attack carbonyl carbons, and the hydrolysis reaction is more rapid. The products are carboxylate and alcohol.
Pyridine ring and pyrrole ring also give this compound another chemical activity. The nitrogen atom of the pyrrole ring has a lone pair of electrons, which is weakly basic and can react with acids to form salts or with electrophilic reagents. The π electron cloud density of the pyrrole ring is high, which is prone to electrophilic substitution, and the substitution check point is mostly at the position of higher electron cloud density. The chlorine atom can participate in the nucleophilic substitution reaction. Because the carbon-chlorine bond has a certain polarity, the nucleophilic reagent is easy to attack the carbon atom connected to the chlorine, causing the chlorine atom to be replaced.
The chemical properties of ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid esters are determined by the synergy of their functional groups and cyclic structures, and may have important uses in organic synthesis and other fields.

There are various ways to synthesize ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid esters. One is to use a suitable pyridine derivative as the starting material. The pyridine ring is first specially modified to introduce chlorine atoms at a specific position, which can be achieved by halogenation. The choice of halogenating agent is quite critical, such as chlorination reagents, under suitable reaction conditions, such as suitable temperature and solvent environment, interact with pyridine derivatives to introduce 6-chlorine atoms precisely.
Then, for the 2-position of the pyridine ring, carboxylic acid esterification is carried out. The corresponding carboxylic acid or its active derivatives, such as acid chloride, acid anhydride, etc., are often reacted with ethanol in the presence of a catalyst. If the acid chloride is taken as an example, with the help of organic bases such as triethylamine and other acid binding agents, the acid chloride and ethanol undergo a smooth esterification reaction, so that the carboxylic acid ethyl ester structure is constructed at the 2-position of the pyridine ring, and the final result is ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylate.
In addition, there are also pyrrole derivatives as starting materials. The fused structure of pyrrole ring and pyridine ring is first constructed, and the reaction steps and conditions need to be carefully designed in this process. Or by means of cyclization reaction, in a specific reagent and reaction environment, pyrrole and pyridine structures are connected to form a pyrrolido [2,3-b] pyridine skeleton. After that, according to the previous method, chlorine atoms are introduced at the 6-position first, and then carboxylic acid esterification at the 2-position is carried out, which can also achieve the purpose of synthesis. Both of these are common routes for the preparation of ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid esters.

Ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid esters are widely used in the field of organic synthesis.
One of them is often the key intermediate for the preparation of a variety of nitrogen-containing heterocyclic compounds. Nitrogen-containing heterocyclic compounds are of great significance in the fields of medicine, pesticides, materials, etc. In medicine, many bioactive drug molecules contain this heterocyclic structural unit. For example, through the specific chemical reaction of p-ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid ester, such as the substitution reaction with amine compounds, new compounds with potential pharmacological activity can be constructed, or they can be used to develop new drugs for the treatment of specific diseases.
Second, in the field of pesticide research and development, this compound also plays an important role. It can be used as a starting material for the synthesis of new pesticides, and through a series of reactions, it can generate pesticide ingredients that have high killing or inhibitory effects on pests. Due to its unique chemical structure, the synthesized pesticides may have the advantages of high selectivity and low toxicity, which is in line with the current development trend of green pesticides.
Third, in the field of materials science, materials based on ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid esters may exhibit special optical and electrical properties. For example, it can be used to prepare organic Light Emitting Diode (OLED) materials. Its unique molecular structure may endow the materials with excellent luminous properties and improve the luminous efficiency and stability of OLED devices.
In conclusion, ethyl 6-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid ester, with its unique chemical structure, has significant uses in many important fields, providing a key material basis for innovation and development in various fields.

I have not heard the exact price of "ethyl+6-chloro-1H-pyrrolo%5B2%2C3-b%5Dpyridine-2-carboxylate" in the market. This is a fine chemical substance, and its price often varies depending on quality, purity, supply and demand, quantity purchased, and vendors.
If it is of high purity and specially made for scientific research, it is suitable for high-end experiments, and the price is not cheap; if the purity is slightly lower, it is used for general industrial use, and the price is slightly lower. If the market oversupply, the price will also decline; if the demand exceeds the supply, the price will rise.
When purchasing in bulk, due to large quantities, vendors may give discounts, and the price will also vary. And different regions, due to different logistics, taxes, etc., the price also varies. Therefore, if you want to know the exact price range, you need to consult chemical raw material suppliers, chemical reagents, or explore on the chemical product trading platform in order to obtain a more accurate price based on the actual situation at that time.

This "ethyl + 6 - chloro - 1H - pyrrolo [2,3 - b] pyridine - 2 - carboxylate" is an organic chemical substance, the Chinese name is or 6 - chloro - 1H - pyrrole - [2,3 - b] pyridine - 2 - carboxylate ethyl ester. Its manufacturer, in the field of current chemical industry, has many companies involved.
Foreign companies such as Sigma - Aldrich have a long reputation and focus on fine chemicals. The preparation process of such compounds is mature, and the product purity is quite high. It is supplied to many scientific research institutions and enterprises around the world.
There are also many manufacturers in China. For example, Bering Wei Technology Co., Ltd. often provides a variety of specifications of such products to meet the needs of different customers. Its production follows strict standards and quality control is rigorous.
Another example is Tixi Ai (Shanghai) Chemical Industry Development Co., Ltd., which inherits Japanese technology and has advanced production technology. From the selection of raw materials to the output of finished products, there are fine processes for the compound to ensure stable product quality.
However, in chemical production, the product characteristics of local manufacturers may vary slightly due to differences in technology and equipment. Buyers need to carefully check the product parameters and word-of-mouth of each factory according to their own uses to select the appropriate manufacturer. This compound has a wide range of uses and is of important value in pharmaceutical research and development, organic synthesis and other fields. Manufacturers are also constantly improving their technology in order to better meet the needs of the market.