Ethyl 5 Methoxy 1h Pyrrolo 2 3 C Pyridine 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate

    Specifications

    HS Code

    497837

    Name Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
    Molecular Formula C11H12N2O3
    Molecular Weight 220.225 g/mol
    Appearance Typically a solid, color may vary depending on purity
    Solubility Solubility characteristics would depend on the solvent, may have some solubility in organic solvents like ethanol, dichloromethane etc.

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    What is the chemical structure of pyridine-2-carboxylate Ethyl 5-methoxy-1H-pyrrolo [2,3-c]
    Ethyl+5-methoxy-1H-pyrrolo%5B2%2C3-c%5Dpyridine-2-carboxylate, this is the English name of an organic compound. Dissecting and analyzing it, "Ethyl" means "ethyl", indicating that the compound contains ethyl group; "5-methoxy" means "5-methoxy", indicating the presence of methoxy at a specific position; "1H-pyrrolo% 5B2% 2C3-c% 5Dpyridine" represents a nitrogen-containing heterocyclic structure, which is a special structure formed by the fusing of pyrrole and pyridine; "2-carboxylate" means "2-carboxylate", which means that the carboxylate group is connected to the No. 2 position of the fused ring structure.
    Overall, the chemical structure of this compound is that there is a methoxy group at the 5th position of 1H-pyrrolido [2,3-c] pyridine, and the 2nd position is connected to the ethyl carboxylate group. Its structure can be roughly described as follows: the fused ring system of pyrrolido-pyridine is used as the core structure, and the methoxy group is extended at the 5th position of the fused ring, and the 2nd position is connected to the side chain of ethyl carboxylate composed of carbon, hydrogen, and oxygen atoms. This structure endows the compound with specific physical and chemical properties, which may have important application value in organic synthesis, medicinal chemistry, and other fields.
    What are the main uses of Ethyl 5-methoxy-1H-pyrrolo [2,3-c] pyridine-2-carboxylate
    Ethyl+5-methoxy-1H-pyrrolo%5B2%2C3-c%5Dpyridine-2-carboxylate is 5-methoxy-1H-pyrrolido [2,3-c] pyridine-2-carboxylate ethyl ester, which has a wide range of uses.
    In the field of pharmaceutical chemistry, it is often the key intermediate for the creation of new drugs. Because the nitrogen-containing heterocyclic structure is quite common in many drug active molecules, the unique structure of this compound can be used by organic synthesis to add different functional groups to derive a variety of compounds with biological activities, such as antibacterial, antitumor, antiviral drugs, etc., or can act on specific biological targets, which is of great significance for the treatment of diseases.
    In the field of materials science, nitrogen-containing heterocyclic compounds often have unique optoelectronic properties. Ethyl 5-methoxy-1H-pyrrolio [2,3-c] pyridine-2-carboxylate can be used as raw materials for the preparation of organic optoelectronic materials, such as organic Light Emitting Diode (OLED) and organic solar cells, which can improve the charge transport performance and luminous efficiency of materials.
    In the field of organic synthetic chemistry, it can be used as a key synthetic building block. By virtue of its intra-molecular activity checking point, various organic reactions, such as nucleophilic substitution, electrophilic substitution, cyclization reaction, etc., can construct more complex polycyclic or heterocyclic compounds, expand the route of organic synthesis, provide the possibility for the synthesis of organic compounds with novel structures, and help the progress of organic synthetic chemistry.
    What are the synthetic methods of Ethyl 5-methoxy-1H-pyrrolo [2,3-c] pyridine-2-carboxylate
    In order to obtain Ethyl 5-methoxy-1H-pyrrolo [2,3-c] pyridine-2-carboxylate, the following ancient methods can be used.
    First, a pyridine derivative containing a specific substituent is used as the starting material. The first step is to react with a methoxylation reagent with appropriate activity. This step needs to be carried out under suitable reaction conditions, such as in a specific solvent, at an appropriate temperature and catalyzed by a base, so that a methoxy group is introduced at a specific position on the pyridine ring to obtain a methoxylation intermediate. Thereafter, the intermediate is reacted with a reagent that can introduce a pyrrole ring. This reaction may require a specific catalyst and reaction environment to construct a pyrrole ring through cyclization to generate a compound containing the desired pyrrolido-pyridine structure. Finally, it interacts with the carboxylic acid ethylation reagent to achieve the introduction of ethyl ester group, and finally obtains Ethyl 5-methoxy-1H-pyrrolo [2,3-c] pyridine-2-carboxylate.
    Second, it can also start from the other side. Starting with the pyrrole derivative, the pyrrole ring is modified first, such as introducing a suitable substituent, so that it has an active check point for building a connection with the pyridine ring. After that, through specific reaction conditions, the condensation reaction with the pyrrolide derivative occurs to form a pyrrolido-pyridine skeleton. In this process, the reaction conditions need to be carefully adjusted to ensure the selectivity of the reaction check point. Then, on the obtained skeleton, the introduction of methoxy groups and the construction of ethyl ester groups are carried out in sequence. Methoxylation can be achieved by suitable methoxylation reagents and reaction conditions, while the introduction of ethyl ester groups requires the selection of appropriate esterification methods and reagents, such as the reaction of the corresponding alcohol and carboxylic acid derivatives under catalytic conditions.
    When preparing this compound, the conditions of each step of the reaction and the selection of reagents are crucial, and fine control is required to obtain the target product.
    What are the physical properties of Ethyl 5-methoxy-1H-pyrrolo [2,3-c] pyridine-2-carboxylate
    Ethyl+5-methoxy-1H-pyrrolo%5B2%2C3-c%5Dpyridine-2-carboxylate, this is an organic compound, often referred to as 5-methoxy-1H-pyrrolido [2,3-c] pyridine-2-carboxylate ethyl ester. Its physical properties are related to its existence form, melting point, solubility, etc., and are very important in the field of organic synthesis and medicinal chemistry.
    Looking at its properties, it is either a solid or a liquid under normal conditions, depending on the intermolecular force and structure. If the intermolecular force is strong and the arrangement is orderly, it tends to be solid; conversely, the force is weak, the arrangement is disordered, or it is liquid.
    In terms of melting and boiling point, due to the fact that the molecule contains polar groups, such as methoxy group (-OCH 😉) and ester group (-COOCH ⃣ CH 😉), the polar action enhances the attractive force between molecules, and the melting and boiling point may be relatively high. Methoxy groups can form weak intermolecular forces. Carbonyl groups and ethoxy groups in ester groups participate in dipole-dipole interactions, which all affect the melting and boiling point.
    In terms of solubility, in view of its polar groups, it may have a certain solubility in polar organic solvents such as ethanol and acetone. Hydrogen bonds or dipole-dipole interactions are formed between polar solvents and polar groups of compounds to help them dissolve. However, in non-polar solvents, such as n-hexane and benzene, the solubility may be low due to large polar differences.
    In addition, the density of the compound may be similar to that of common organic compounds, depending on the ratio of molecular weight to volume. And it has certain stability, but under specific conditions, such as strong acid, strong base or high temperature, its ester groups and other functional groups may react, and the stability is affected.
    Ethyl 5-methoxy-1H-pyrrolo [2,3-c] pyridine-2-carboxylate market prospects
    Ethyl+5-methoxy-1H-pyrrolo%5B2%2C3-c%5Dpyridine-2-carboxylate, that is, 5-methoxy-1H-pyrrole [2,3-c] ethyl pyridine-2-carboxylate, this compound has both opportunities and challenges in terms of market prospects.
    Looking at its use, this compound has great potential in the field of pharmaceutical research and development. Many compounds with nitrogen-containing heterocyclic structures have shown unique biological activities or can be used to create new drugs. Ethyl 5-methoxy-1H-pyrrole [2,3-c] pyridine-2-carboxylate, as a nitrogen-containing heterocyclic derivative, or has biological activities such as anti-inflammation and anti-tumor. Over time, after in-depth research and development, it is expected to become a key ingredient of new drugs. The demand for it in the pharmaceutical market may be growing.
    Furthermore, in the field of organic synthesis, such compounds can be used as key intermediates. The development of organic synthesis chemistry is changing with each passing day, and the demand for intermediates with novel structures and unique properties is constantly increasing. The special structure of 5-methoxy-1H-pyrrolido [2,3-c] pyridine-2-carboxylate ethyl ester may provide organic synthesis chemists with new ideas for building more complex organic molecules, so there is still room for development in the organic synthesis reagent market.
    However, its marketing activities also face challenges. First, research and development costs are high. From the discovery of biological activities, to the development of pharmacological research and clinical trials, a huge amount of money and a lot of time are required. If the research and development process encounters difficulties or is stalled due to lack of funds. Secondly, the competition is fierce. The field of medicine and organic synthesis is developing rapidly, and many scientific research institutions and enterprises are engaged in the research and development of new compounds. Compounds with similar structures or existing competitors need to have unique advantages if they want to stand out.
    Although the market prospect of 5-methoxy-1H-pyrrolido [2,3-c] pyridine-2-carboxylate ethyl ester is uncertain, with its potential value in the field of medicine and organic synthesis, if it can properly meet the challenges, it is still expected to find development opportunities in the market.